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Institution

Osaka University

EducationOsaka, Japan
About: Osaka University is a education organization based out in Osaka, Japan. It is known for research contribution in the topics: Laser & Population. The organization has 83778 authors who have published 185669 publications receiving 5158122 citations. The organization is also known as: Ōsaka daigaku.
Topics: Laser, Population, Catalysis, Thin film, Gene


Papers
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Journal ArticleDOI
TL;DR: The link between specific mutations in HATs and the primary inherited aminoacidurias, cystinuria and lysinuric protein intolerance is described.

487 citations

Journal ArticleDOI
TL;DR: The results indicate that the amphioxus genome is elemental to an understanding of the biology and evolution of nonchordate deuterostomes, invertebrate chordates, and vertebrates.
Abstract: Cephalochordates, urochordates, and vertebrates evolved from a common ancestor over 520 million years ago To improve our understanding of chordate evolution and the origin of vertebrates, we intensively searched for particular genes, gene families, and conserved noncoding elements in the sequenced genome of the cephalochordate Branchiostoma floridae, commonly called amphioxus or lancelets Special attention was given to homeobox genes, opsin genes, genes involved in neural crest development, nuclear receptor genes, genes encoding components of the endocrine and immune systems, and conserved cis-regulatory enhancers The amphioxus genome contains a basic set of chordate genes involved in development and cell signaling, including a fifteenth Hox gene This set includes many genes that were co-opted in vertebrates for new roles in neural crest development and adaptive immunity However, where amphioxus has a single gene, vertebrates often have two, three, or four paralogs derived from two whole-genome duplication events In addition, several transcriptional enhancers are conserved between amphioxus and vertebrates--a very wide phylogenetic distance In contrast, urochordate genomes have lost many genes, including a diversity of homeobox families and genes involved in steroid hormone function The amphioxus genome also exhibits derived features, including duplications of opsins and genes proposed to function in innate immunity and endocrine systems Our results indicate that the amphioxus genome is elemental to an understanding of the biology and evolution of nonchordate deuterostomes, invertebrate chordates, and vertebrates

487 citations

Journal ArticleDOI
Ken Ishii1, Shohei Koyama1, Atsushi Nakagawa1, Cevayir Coban1, Shizuo Akira1 
TL;DR: Continuing mapping of the complex networks of host-microbe interactions may improve the understanding of self/non-self discrimination in immunity and its intervention.

487 citations

Journal ArticleDOI
TL;DR: Les interactions phonons optiques-electrons sont etudiees dans des heterostructures simples et doubles dans l'aide des modes propres orthonormaux des phonons calcule dans le modele du continuum dielectrique.
Abstract: Electron--optical-phonon interactions are studied in single and double heterostructures. The Hamiltonian describing electron-phonon interactions is derived with use of orthonormal eigenmodes of phonons calculated in the dielectric continuum model. Effects of interactions are expressed in the form of an effective electron-electron interaction mediated by virtual exchange of phonons. It is given by the sum of products of coupling constants and form factors for different modes. The coupling constants correspond to the Fr\"ohlich coupling constant in bulk and the form factors describe effects of electron confinement. The resulting expression is convenient and useful in discussing relative importance of interface modes and bulklike confined modes and also in exploring the possibility of reduction of electron--optical-phonon interactions in heterostructures. It is applied to calculations of the polaron mobility and magnetophonon resonance spectra. The results clearly demonstrate roles of interface phonons.

487 citations


Authors

Showing all 84130 results

NameH-indexPapersCitations
Shizuo Akira2611308320561
Thomas C. Südhof191653118007
Tadamitsu Kishimoto1811067130860
Yusuke Nakamura1792076160313
H. S. Chen1792401178529
Hyun-Chul Kim1764076183227
Masayuki Yamamoto1711576123028
Kenji Kangawa1531117110059
Jongmin Lee1502257134772
Yoshio Bando147123480883
Takeo Kanade147799103237
Olaf Reimer14471674359
Yuji Matsuzawa143836116711
Kim Nasmyth14229459231
Tasuku Honjo14171288428
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023139
2022637
20216,914
20206,865
20196,462
20186,189