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Institution

Oswaldo Cruz Foundation

FacilityRio de Janeiro, Brazil
About: Oswaldo Cruz Foundation is a facility organization based out in Rio de Janeiro, Brazil. It is known for research contribution in the topics: Population & Trypanosoma cruzi. The organization has 18673 authors who have published 36752 publications receiving 802378 citations. The organization is also known as: Fundação Oswaldo Cruz & FIOCRUZ.


Papers
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Journal ArticleDOI
Bin Zhou1, James Bentham1, Mariachiara Di Cesare2, Honor Bixby1  +787 moreInstitutions (231)
TL;DR: The number of adults with raised blood pressure increased from 594 million in 1975 to 1·13 billion in 2015, with the increase largely in low-income and middle-income countries, and the contributions of changes in prevalence versus population growth and ageing to the increase.

1,573 citations

Journal ArticleDOI
24 Dec 2009-Cell
TL;DR: It is suggested that this Wolbachia-mediated pathogen interference may work synergistically with the life-shortening strategy proposed previously to provide a powerful approach for the control of insect transmitted diseases.

1,404 citations

Journal ArticleDOI
TL;DR: Global rates of change suggest that only 16 countries will achieve the MDG 5 target by 2015, with evidence of continued acceleration in the MMR, and MMR was highest in the oldest age groups in both 1990 and 2013.

1,383 citations

Journal ArticleDOI
Najib M. El-Sayed1, Peter J. Myler2, Peter J. Myler3, Daniella Castanheira Bartholomeu4, Daniel Nilsson5, Gautam Aggarwal2, Anh-Nhi Tran5, Elodie Ghedin1, Elizabeth A. Worthey2, Arthur L. Delcher, Gaëlle Blandin4, Scott J. Westenberger6, Elisabet Caler4, Gustavo C. Cerqueira7, Carole Branche5, Brian J. Haas4, Atashi Anupama2, Erik Arner5, Lena Åslund8, Philip Attipoe2, Esteban J. Bontempi5, Frédéric Bringaud9, Peter Burton10, Eithon Cadag2, David A. Campbell6, Mark Carrington11, Jonathan Crabtree4, Hamid Darban5, José Franco da Silveira12, Pieter J. de Jong13, Kimberly Edwards5, Paul T. Englund14, Gholam Fazelina2, Tamara Feldblyum4, Marcela Ferella5, Alberto C.C. Frasch15, Keith Gull16, David Horn17, Lihua Hou4, Yiting Huang2, Ellen Kindlund5, Michele M. Klingbeil18, Sindy Kluge5, Hean Koo4, Daniela R. Lacerda19, Mariano J. Levin20, Hernan Lorenzi20, Tin Louie2, Carlos Renato Machado7, Richard McCulloch10, Alan McKenna5, Yumi Mizuno5, Jeremy C. Mottram10, Siri Nelson2, Stephen Ochaya5, Kazutoyo Osoegawa13, Grace Pai4, Marilyn Parsons2, Marilyn Parsons3, Martin Pentony2, Ulf Pettersson8, Mihai Pop4, José Luis Ramírez21, Joel Rinta2, Laura Robertson2, Steven L. Salzberg, Daniel O. Sánchez15, Amber Seyler2, Reuben Sunil Kumar Sharma11, Jyoti Shetty4, Anjana J. Simpson4, Ellen Sisk2, Martti T. Tammi5, Martti T. Tammi22, Rick L. Tarleton23, Santuza M. R. Teixeira7, Susan Van Aken4, Christy Vogt2, Pauline N. Ward10, Bill Wickstead16, Jennifer R. Wortman4, Owen White4, Claire M. Fraser4, Kenneth Stuart3, Kenneth Stuart2, Björn Andersson5 
15 Jul 2005-Science
TL;DR: Although the Tritryp lack several classes of signaling molecules, their kinomes contain a large and diverse set of protein kinases and phosphatases; their size and diversity imply previously unknown interactions and regulatory processes, which may be targets for intervention.
Abstract: Whole-genome sequencing of the protozoan pathogen Trypanosoma cruzi revealed that the diploid genome contains a predicted 22,570 proteins encoded by genes, of which 12,570 represent allelic pairs. Over 50% of the genome consists of repeated sequences, such as retrotransposons and genes for large families of surface molecules, which include trans-sialidases, mucins, gp63s, and a large novel family (>1300 copies) of mucin-associated surface protein (MASP) genes. Analyses of the T. cruzi, T. brucei, and Leishmania major (Tritryp) genomes imply differences from other eukaryotes in DNA repair and initiation of replication and reflect their unusual mitochondrial DNA. Although the Tritryp lack several classes of signaling molecules, their kinomes contain a large and diverse set of protein kinases and phosphatases; their size and diversity imply previously unknown interactions and regulatory processes, which may be targets for intervention.

1,349 citations

Journal ArticleDOI
26 Jul 2016-eLife
TL;DR: The height differential between the tallest and shortest populations was 19-20 cm a century ago, and has remained the same for women and increased for men a century later despite substantial changes in the ranking of countries.
Abstract: Being taller is associated with enhanced longevity, and higher education and earnings. We reanalysed 1472 population-based studies, with measurement of height on more than 18.6 million participants to estimate mean height for people born between 1896 and 1996 in 200 countries. The largest gain in adult height over the past century has occurred in South Korean women and Iranian men, who became 20.2 cm (95% credible interval 17.5–22.7) and 16.5 cm (13.3–19.7) taller, respectively. In contrast, there was little change in adult height in some sub-Saharan African countries and in South Asia over the century of analysis. The tallest people over these 100 years are men born in the Netherlands in the last quarter of 20th century, whose average heights surpassed 182.5 cm, and the shortest were women born in Guatemala in 1896 (140.3 cm; 135.8–144.8). The height differential between the tallest and shortest populations was 19-20 cm a century ago, and has remained the same for women and increased for men a century later despite substantial changes in the ranking of countries.

1,348 citations


Authors

Showing all 18833 results

NameH-indexPapersCitations
Douglas T. Golenbock12331761267
Guy A. Zimmerman10932839740
David Brown105125746827
Liam Smeeth10475353433
Ann M. Dvorak9943741073
David C. Spray9540028732
Theodore A. Slotkin8957530070
Fernando Q. Cunha8868231501
Mauro M. Teixeira8671331301
Ricardo T. Gazzinelli8634028233
Peter F. Weller8533122005
João B. Calixto8146023029
Frederic J. Seidler8037219564
João Santana da Silva8039919060
Deborah Carvalho Malta7770661000
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202334
2022250
20212,842
20202,942
20192,404
20182,302