Institution
Pacific Northwest National Laboratory
Facility•Richland, Washington, United States•
About: Pacific Northwest National Laboratory is a facility organization based out in Richland, Washington, United States. It is known for research contribution in the topics: Catalysis & Aerosol. The organization has 11581 authors who have published 27934 publications receiving 1120489 citations. The organization is also known as: PNL & PNNL.
Topics: Catalysis, Aerosol, Mass spectrometry, Ion, Adsorption
Papers published on a yearly basis
Papers
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North Dakota State University1, Australian National University2, Commonwealth Scientific and Industrial Research Organisation3, Argonne National Laboratory4, University of the District of Columbia5, Qatar University6, Chinese Academy of Sciences7, Pacific Northwest National Laboratory8, University of Sydney9
TL;DR: The main aim of this paper is to identify open challenges associated with energy efficient resource allocation and outline the problem and existing hardware and software-based techniques available for this purpose based on the energy-efficient research dimension taxonomy.
Abstract: In a cloud computing paradigm, energy efficient allocation of different virtualized ICT resources (servers, storage disks, and networks, and the like) is a complex problem due to the presence of heterogeneous application (e.g., content delivery networks, MapReduce, web applications, and the like) workloads having contentious allocation requirements in terms of ICT resource capacities (e.g., network bandwidth, processing speed, response time, etc.). Several recent papers have tried to address the issue of improving energy efficiency in allocating cloud resources to applications with varying degree of success. However, to the best of our knowledge there is no published literature on this subject that clearly articulates the research problem and provides research taxonomy for succinct classification of existing techniques. Hence, the main aim of this paper is to identify open challenges associated with energy efficient resource allocation. In this regard, the study, first, outlines the problem and existing hardware and software-based techniques available for this purpose. Furthermore, available techniques already presented in the literature are summarized based on the energy-efficient research dimension taxonomy. The advantages and disadvantages of the existing techniques are comprehensively analyzed against the proposed research dimension taxonomy namely: resource adaption policy, objective function, allocation method, allocation operation, and interoperability.
303 citations
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TL;DR: In this article, the authors review the current understanding of radiation-induced material changes that occur in light-water-reactor (LWR) core components and link them to intergranular failure processes.
303 citations
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TL;DR: Turnover frequencies up to 95,000 h(-1) have now been obtained and even higher rates should be possible using the cocatalyst and amine combinations identified herein, and the possible roles of the alcohol and base are discussed.
Abstract: A trace amount of alcohol cocatalyst and a stoichiometric amount of base are required during the hydrogenation of CO2 to formic acid catalyzed by ruthenium trimethylphosphine complexes. Variation of the choice of alcohol and base causes wide variation in the rate of reaction. Acidic, nonbulky alcohols and triflic acid increase the rate of hydrogenation an order of magnitude above that which can be obtained with traditionally used methanol or water. Similarly, use of DBU rather than NEt3 increases the rate of reaction by an order of magnitude. Turnover frequencies up to 95 000 h-1 have now been obtained, and even higher rates should be possible using the cocatalyst and amine combinations identified herein. Preliminary in situ NMR spectroscopic observations are described, and the possible roles of the alcohol and base are discussed.
303 citations
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TL;DR: The developed computational methods for accurate de novo design of conformationally restricted peptides and the use of these methods to design 18–47 residue, disulfide-crosslinked peptides, a subset of which are heterochiral and/or N–C backbone-cyclized, provide the basis for development of a new generation of peptide-based drugs.
Abstract: Naturally occurring, pharmacologically active peptides constrained with covalent crosslinks generally have shapes that have evolved to fit precisely into binding pockets on their targets. Such peptides can have excellent pharmaceutical properties, combining the stability and tissue penetration of small-molecule drugs with the specificity of much larger protein therapeutics. The ability to design constrained peptides with precisely specified tertiary structures would enable the design of shape-complementary inhibitors of arbitrary targets. Here we describe the development of computational methods for accurate de novo design of conformationally restricted peptides, and the use of these methods to design 18-47 residue, disulfide-crosslinked peptides, a subset of which are heterochiral and/or N-C backbone-cyclized. Both genetically encodable and non-canonical peptides are exceptionally stable to thermal and chemical denaturation, and 12 experimentally determined X-ray and NMR structures are nearly identical to the computational design models. The computational design methods and stable scaffolds presented here provide the basis for development of a new generation of peptide-based drugs.
302 citations
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Massachusetts Institute of Technology1, National Center for Atmospheric Research2, University of Arkansas at Little Rock3, Saint Louis University4, Pacific Northwest National Laboratory5, Langley Research Center6, University of Colorado Boulder7, Washington State University8, National Autonomous University of Mexico9, Ames Research Center10, University of Wisconsin-Madison11, Indiana University12
TL;DR: The Mexico City Metropolitan Area (MCMA) was selected as the case study to characterize the sources, concentrations, transport, and transformation processes of the gases and fine particles emitted to the MCMA atmosphere and to evaluate the regional and global impacts of these emissions as mentioned in this paper.
Abstract: . MILAGRO (Megacity Initiative: Local And Global Research Observations) is an international collaborative project to examine the behavior and the export of atmospheric emissions from a megacity. The Mexico City Metropolitan Area (MCMA) – one of the world's largest megacities and North America's most populous city – was selected as the case study to characterize the sources, concentrations, transport, and transformation processes of the gases and fine particles emitted to the MCMA atmosphere and to evaluate the regional and global impacts of these emissions. The findings of this study are relevant to the evolution and impacts of pollution from many other megacities. The measurement phase consisted of a month-long series of carefully coordinated observations of the chemistry and physics of the atmosphere in and near Mexico City during March 2006, using a wide range of instruments at ground sites, on aircraft and satellites, and enlisting over 450 scientists from 150 institutions in 30 countries. Three ground supersites were set up to examine the evolution of the primary emitted gases and fine particles. Additional platforms in or near Mexico City included mobile vans containing scientific laboratories and mobile and stationary upward-looking lidars. Seven instrumented research aircraft provided information about the atmosphere over a large region and at various altitudes. Satellite-based instruments peered down into the atmosphere, providing even larger geographical coverage. The overall campaign was complemented by meteorological forecasting and numerical simulations, satellite observations and surface networks. Together, these research observations have provided the most comprehensive characterization of the MCMA's urban and regional atmospheric composition and chemistry that will take years to analyze and evaluate fully. In this paper we review over 120 papers resulting from the MILAGRO/INTEX-B Campaign that have been published or submitted, as well as relevant papers from the earlier MCMA-2003 Campaign, with the aim of providing a road map for the scientific community interested in understanding the emissions from a megacity such as the MCMA and their impacts on air quality and climate. This paper describes the measurements performed during MILAGRO and the results obtained on MCMA's atmospheric meteorology and dynamics, emissions of gases and fine particles, sources and concentrations of volatile organic compounds, urban and regional photochemistry, ambient particulate matter, aerosol radiative properties, urban plume characterization, and health studies. A summary of key findings from the field study is presented.
302 citations
Authors
Showing all 11848 results
Name | H-index | Papers | Citations |
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Yi Cui | 220 | 1015 | 199725 |
Derek R. Lovley | 168 | 582 | 95315 |
Xiaoyuan Chen | 149 | 994 | 89870 |
Richard D. Smith | 140 | 1180 | 79758 |
Taeghwan Hyeon | 139 | 563 | 75814 |
Jun Liu | 138 | 616 | 77099 |
Federico Capasso | 134 | 1189 | 76957 |
Jillian F. Banfield | 127 | 562 | 60687 |
Mary M. Horowitz | 127 | 557 | 56539 |
Frederick R. Appelbaum | 127 | 677 | 66632 |
Matthew Jones | 125 | 1161 | 96909 |
Rainer Storb | 123 | 905 | 58780 |
Zhifeng Ren | 122 | 695 | 71212 |
Wei Chen | 122 | 1946 | 89460 |
Thomas E. Mallouk | 122 | 549 | 52593 |