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Showing papers by "Panasonic published in 2022"


Journal ArticleDOI
Daisuke Ino1
TL;DR: In this paper , a G-protein-coupled receptor-based green fluorescent OT sensor was proposed for real-time detection of brain OT dynamics in living mice by combining viral gene delivery and fiber photometry-mediated fluorescence measurements.
Abstract: Oxytocin (OT), a hypothalamic neuropeptide that acts as a neuromodulator in the brain, orchestrates a variety of animal behaviors. However, the relationship between brain OT dynamics and complex animal behaviors remains largely elusive, partly because of the lack of a suitable technique for its real-time recording in vivo. Here, we describe MTRIAOT, a G-protein-coupled receptor-based green fluorescent OT sensor that has a large dynamic range, suitable affinity, ligand specificity for OT orthologs, minimal effects on downstream signaling and long-term fluorescence stability. By combining viral gene delivery and fiber photometry-mediated fluorescence measurements, we demonstrate the utility of MTRIAOT for real-time detection of brain OT dynamics in living mice. MTRIAOT-mediated measurements indicate variability of OT dynamics depending on the behavioral context and physical condition of an animal. MTRIAOT will likely enable the analysis of OT dynamics in a variety of physiological and pathological processes.

12 citations


Journal ArticleDOI
TL;DR: In this article, the authors investigated the dynamic temperature behavior around a melt pool in metal-based powder bed fusion using a laser beam (PBF-LB/M) to clarify the influence of the associated morphological changes of the metal powder experimentally.

4 citations


Journal ArticleDOI
Yoshinao Harada1
TL;DR: Kamikihito, a traditional Japanese Kampo medicine, has been widely used to date in treating anxiety and neurosis in Japan as mentioned in this paper , has been shown to improve psychological and gastrointestinal symptoms in patients with chronic constipation.

1 citations


Journal ArticleDOI
Pongsak Lasang1
10 Dec 2022-Sensors
TL;DR: In this article , a boundary-encouraging local frame reference, PyramidFeature(PMD), consisting of point-level, line-level and mesh-level information, is proposed to encourage the knowledge of boundaries to overcome the normal ambiguity.
Abstract: Point Cloud Registration contributes a lot to measuring, monitoring, and simulating in building information modeling (BIM). In BIM applications, the robustness and generalization of point cloud features are particularly important due to the huge differences in sampling environments. We notice two possible factors that may lead to poor generalization, the normal ambiguity of boundaries on hard edges leading to less accuracy in transformation; and the fact that existing methods focus on spatial transformation accuracy, leaving the advantages of feature matching unaddressed. In this work, we propose a boundary-encouraging local frame reference, the PyramidFeature(PMD), consisting of point-level, line-level, and mesh-level information to extract a more generalizing and continuous point cloud feature to encourage the knowledge of boundaries to overcome the normal ambiguity. Furthermore, instead of registration guided by spatial transformation accuracy alone, we suggest another supervision to extract consistent hybrid features. A large number of experiments have demonstrated the superiority of our PyramidNet (PMDNet), especially when the training (ModelNet40) and testing (BIM) sets are very different, PMDNet still achieves very high scalability.

Book ChapterDOI
Jeffrey Merritt1
06 Jul 2022
TL;DR: In this paper , the authors give insights, suggestions, and basic guidelines to set you on the path to achieving success by continuous education, creating and implementation of SOP, CIP, COP and PM programs.
Abstract: Cleaning and sanitization are an integral part of your process and regardless of how well your plant is designed and if not done properly, it will directly impact the quality of your finished product. This chapter will give you insights into how the cleaning and sanitization of aseptic processing and packaging equipment will help you on the path to producing safe, quality product to meet your goals. It demonstrates that the commitment to “Do It Right the First Time” is a top-down commitment. The aseptic processing and packaging process is complex, this chapter will give insights, suggestions, and basic guidelines to set you on the path to achieving success. It will show that through continuous education, creating and implementation of SOP, CIP, COP, and PM programs, you will be more efficient in producing and reaching your production goals with “quality case count” that is salable product, which directly impacts the company’s bottom line. The chapter covers the steps and programs such as validation, verification, passivation, change control and environmental control, to help you in the cleaning and sanitization of your aseptic and processing equipment.

Journal ArticleDOI
Jayagopal P B1
TL;DR: For example, this article argued that the glamour of big tech was associated with the glamor of motion: of speed, of power, and the thrill of exploring new frontiers.
Abstract: Today, the phrase “big tech” resonates negatively. It conjures up disturbing aspects of social media and the rise of megacorporations that seem beyond the reach of the law. And yet decades ago, big tech was associated with the glamour of motion: of speed, of power, and the thrill of exploring new frontiers.

Journal ArticleDOI
Andreas T. Haka1
TL;DR: For the rest of this century, humankind will be building cities at an unprecedented pace, and much of that increase will occur in parts of the world that lag in infrastructure as mentioned in this paper .
Abstract: For the rest of this century, humankind will be building cities at an unprecedented pace. World population is projected to increase from 7.9 billion to more than 10 billion, and much of that increase will occur in parts of the world that lag in infrastructure. Everywhere, people will expect to catch up, and then surpass. China is an example of how this can happen in just 30 years.