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Paris West University Nanterre La Défense

EducationParis, France
About: Paris West University Nanterre La Défense is a education organization based out in Paris, France. It is known for research contribution in the topics: Population & Finite element method. The organization has 895 authors who have published 1430 publications receiving 21712 citations.


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Journal ArticleDOI
TL;DR: A new computational method called LOTUS is proposed to predict new driver genes, a machine-learning based approach which allows to integrate various types of data in a versatile manner, including information about gene mutations and protein-protein interactions, and can predict cancer driver genes in a pan-cancer setting as well as for specific cancer types.
Abstract: Cancer driver genes, i.e., oncogenes and tumor suppressor genes, are involved in the acquisition of important functions in tumors, providing a selective growth advantage, allowing uncontrolled proliferation and avoiding apoptosis. It is therefore important to identify these driver genes, both for the fundamental understanding of cancer and to help finding new therapeutic targets or biomarkers. Although the most frequently mutated driver genes have been identified, it is believed that many more remain to be discovered, particularly for driver genes specific to some cancer types. In this paper, we propose a new computational method called LOTUS to predict new driver genes. LOTUS is a machine-learning based approach which allows to integrate various types of data in a versatile manner, including information about gene mutations and protein-protein interactions. In addition, LOTUS can predict cancer driver genes in a pan-cancer setting as well as for specific cancer types, using a multitask learning strategy to share information across cancer types. We empirically show that LOTUS outperforms five other state-of-the-art driver gene prediction methods, both in terms of intrinsic consistency and prediction accuracy, and provide predictions of new cancer genes across many cancer types.

24 citations

Journal ArticleDOI
TL;DR: In this article, the authors study decentralization in public decision-making as the possibility for local authorities to sign incentive contracts with local agents in a context of asymmetric information, where national authorities have better information on their agents but less bargaining power than central authorities at the community level.

24 citations

Journal ArticleDOI
TL;DR: In this article, a low profile planar vortex beam generator is proposed based on microwave frequency selective surface (FSS), which is capable of generating orbital angular momentum (OAM) mode under circularly polarized incidence.
Abstract: In this article, a new technique to design a low-profile planar vortex beam generator is proposed based on microwave frequency selective surface (FSS), which is capable of generating orbital angular momentum (OAM) mode under circularly polarized incidence. Such OAM generator is composed of transmissive units distributed over a planar surface. Each unit cell, behaving as a spatial phase shifter, is composed of a stack of patches and grids separated by thin dielectric substrates. In order to reduce the thickness of the device, a rectangular patch is embedded in the middle layer to introduce an additional resonance. Compared to other resonant unit cells, this structure presents nearly perfect efficiency to convert circularly polarized incident wave to its cross-polarized component. A simple equivalent circuit model, composed of transmission lines coupled together with shunt capacitors and inductors, is presented to analyze this structure. The prototype of the proposed planar OAM generator operating in $x$ -band is designed, fabricated, and experimentally characterized. Good agreement is achieved between full-wave simulations and measurements. It is demonstrated that the generator can achieve an efficiency of 85% at 10.7 GHz with an overall thickness of $0.067\lambda _{0}$ .

24 citations

Posted ContentDOI
TL;DR: In this article, the authors analyzed the relationship between the set of the Cournot-Nash equilibrium allocations of a strategic market game and its corresponding allocations of the Walras equilibrium allocations in the exchange economy with which it is associated.
Abstract: In this paper, in an exchange economy with atoms and an atomless part, we analyze the relationship between the set of the Cournot-Nash equilibrium allocations of a strategic market game and the set of the Walras equilibrium allocations of the exchange economy with which it is associated. In an example, we show that, even when atoms are countably infinite, Cournot-Nash equilibria yield different allocations from the Walras equilibrium allocations of the underlying exchange economy. We partially replicate the exchange economy by increasing the number of atoms without affecting the atomless part while ensuring that the measure space of agents remains finite. We show that any sequence of Cournot-Nash equilibrium allocations of the strategic mar- ket game associated with the partially replicated exchange economies approximates a Walras equilibrium allocation of the original exchange economy

24 citations

Journal ArticleDOI
TL;DR: In this article, numerical calculation of Green's function can be employed to design conformal metasurfaces of arbitrary geometries within the same framework and without any accommodation, and the alternative approach permits building a meta-surface of meta-atoms with an electric response and significantly simplifying its design and fabrication.
Abstract: The last decade was marked by the advent of the concepts of phase gradient and Huygens' metasurfaces, and simple theoretical models have been leading the research on metasurfaces ever since. Meanwhile, theoretical modeling of nonplanar metasurfaces has appeared to be exceptionally challenging where it demands accurate analysis of the metasurface geometry. The present work addresses this challenge with a radically different theoretical approach demonstrating how numerical calculation of Green's function can be employed to design conformal metasurfaces of arbitrary geometries within the same framework and without any accommodation. Against the classical concepts, the alternative approach permits building a metasurface of meta-atoms with an electric only response and significantly simplifying its design and fabrication. The theory is endorsed experimentally by testing several metasurface prototypes for different beam-forming functionalities: radiation with single or multiple beams in any desired direction.

24 citations


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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202331
2022252
2021146
2020131
2019116
201896