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Institution

ParisTech

EducationParis, France
About: ParisTech is a education organization based out in Paris, France. It is known for research contribution in the topics: Residual stress & Finite element method. The organization has 1888 authors who have published 1965 publications receiving 55532 citations. The organization is also known as: Paris Institute of Technology & ParisTech Développement.


Papers
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Journal ArticleDOI
TL;DR: Selective tibial neurotomy of the soleus nerve induces long-term reduction of reflex hyperexcitability and passive stiffness of plantar flexors in spastic patients, with no lasting impairment of motor efferents.
Abstract: The neuromechanical consequences of tibial neurotomy have not been extensively studied. Fifteen patients were evaluated before and after selective tibial neurotomy (after 2 months and after 15 months) by means of clinical, neurophysiological [tendon (T) reflexes, Hoffmann (H) reflexes and maximum motor response, Mmax] and mechanical parameters (passive stiffness of plantar flexors at the ankle). The neurotomy concerned the soleus (100 % of cases), gastrocnemius (20 % of cases), posterior tibial (60 % of cases) and flexor digitorum longus (47 % of cases) nerves. Neurotomy provided more than 90 % improvement of clinical spasticity scores, 20 % improvement of walking scores and the angle of passive dorsiflexion (APDF) of the ankle (mean angle: 7°), temporary reduction of the soleus Mmax (18 % at 2 months with return to the preoperative value at 15 months), and lasting reduction of the soleus Hmax/Mmax (68 % at 2 months, 78 % at 15 months) and T/Mmax (84 % at 2 months, 80 % at 15 months). M and H responses of the gastrocnemius (whether or not they were included in the neurotomy) were not modified, while T/Mmax decreased to the same degree as for soleus. Passive stiffness was lastingly decreased from 64.0 Nm/rad to 49.0 Nm/rad (2 months) and 49.5 Nm/rad (15 months). Selective tibial neurotomy of the soleus nerve induces long-term reduction of reflex hyperexcitability and passive stiffness of plantar flexors in spastic patients, with no lasting impairment of motor efferents. In parallel, it modifies the tendon reflexes of synergistic muscles (gastrocnemius) not concerned by the neurotomy.

16 citations

Journal ArticleDOI
TL;DR: These findings are the first direct demonstration that successive rearrangements occur, on the same chromosome, in the human T cell receptor gamma locus, and suggest that the chronology of the joining events plays a role in the ontogeny of T cells and their differentiation in gamma/delta + and alpha/beta + lineages.
Abstract: Novel variable (V)--joining (J) gene rearrangements are described in the human T cell receptor gamma locus, in which, on the one hand, the V3 variable gene is joined to the heptamer--nonamer recombination signals of the J1 segment and, on the other hand, the J1 segment is joined to the V3 recombination signals through head-to-head fusion. These recombination products, or hybrid joints, have been originated through an inversion of 47 kb DNA. Interestingly the inverted DNA stretch contains a normal V9-J9 rearrangement. These findings are the first direct demonstration that successive rearrangements occur, on the same chromosome, in the human T cell receptor gamma locus, and suggest that the chronology of the joining events plays a role in the ontogeny of T cells and their differentiation in gamma/delta + and alpha/beta + lineages.

16 citations

Journal ArticleDOI
TL;DR: In this paper, a model of offshoring and non-governmental organizations (NGOs) interacting with multinational firms is presented, where consumers can reduce the incentive for dirty production by financing an NGO monitoring the firm.

16 citations

Journal ArticleDOI
TL;DR: In this article, the authors present the latest development of laser shock adhesion test (LASAT) technology, targeting the weak bond detection in bonded aeronautic structures.

16 citations


Authors

Showing all 1899 results

NameH-indexPapersCitations
Mathias Fink11690051759
George G. Malliaras9438228533
Mickael Tanter8558329452
Gerard Mourou8265334147
Catherine Lapierre7922718286
Carlo Adamo7544436092
Jean-François Joanny7229420700
Marie-Paule Lefranc7238121087
Paul B. Rainey7022217930
Vincent Lepetit7026826207
Bernard Asselain6940923648
Michael J. Baker6939420834
Jacques Prost6819819064
Jean-Philippe Vert6723517593
Jacques Mairesse6631020539
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20239
202212
202174
202093
2019127
2018145