scispace - formally typeset
Search or ask a question
Institution

ParisTech

EducationParis, France
About: ParisTech is a education organization based out in Paris, France. It is known for research contribution in the topics: Residual stress & Finite element method. The organization has 1888 authors who have published 1965 publications receiving 55532 citations. The organization is also known as: Paris Institute of Technology & ParisTech Développement.


Papers
More filters
Journal ArticleDOI
TL;DR: In this article, the authors investigate the frictional behavior of a constrictor type reptile, Python regius, using a specially designed tribo-acoustic probe capable of measuring the coefficient of friction and detecting the acoustical behavior of the skin in vivo.
Abstract: One way of controlling friction and associated energy losses is to engineer a deterministic structural pattern on the surface of the rubbing parts (i.e., texture engineering). Custom texturing enhances the quality of lubrication, reduces friction, and allows the use of lubricants of lower viscosity. To date, a standardized procedure to generate deterministic texture constructs is virtually non-existent. Many engineers, therefore, study natural species to explore surface construction and to probe the role that surface topography assumes in friction control. Snakes offer rich examples of surfaces where topological features allow the optimization and control of frictional behavior. In this paper, we investigate the frictional behavior of a constrictor type reptile, Python regius. The study employed a specially designed tribo-acoustic probe capable of measuring the coefficient of friction and detecting the acoustical behavior of the skin in vivo. The results confirm the anisotropy of the frictional response of snakeskin. The coefficient of friction depends on the direction of sliding: the value in forward motion is lower than that in the converse direction. Detailed analysis of the surface metrological feature reveals that tuning frictional response in snakes originates from the hierarchical nature of surface topology combined to the profile asymmetry of the surface micro-features, and the variation of the curvature of the contacting scales at different body regions. Such a combination affords the reptile the ability to optimize the frictional response.

42 citations

Journal ArticleDOI
TL;DR: This work presents a new technique based on the approximation of the unknown variable (the probability of having a particular chemical state) in terms of a finite sum of separable functions, by using terms as needed in the finite sums decomposition for ensuring convergence.
Abstract: The numerical solution of the chemical master equation (CME) governing gene regulatory networks and cell signaling processes remains a challenging task owing to its complexity, exponentially growing with the number of species involved. Although most of the existing techniques rely on the use of Monte Carlo-like techniques, we present here a new technique based on the approximation of the unknown variable (the probability of having a particular chemical state) in terms of a finite sum of separable functions. In this framework, the complexity of the CME grows only linearly with the number of state space dimensions. This technique generalizes the so-called Hartree approximation, by using terms as needed in the finite sums decomposition for ensuring convergence. But noteworthy, the ease of the approximation allows for an easy treatment of unknown parameters (as is frequently the case when modeling gene regulatory networks, for instance). These unknown parameters can be considered as new space dimensions. In this way, the proposed method provides solutions for any value of the unknown parameters (within some interval of arbitrary size) in one execution of the program.

42 citations

Proceedings ArticleDOI
Hao Li1, Fawzi Nashashibi1
24 Jul 2012
TL;DR: An indirect V2V relative pose estimation method (InDV2VRPE) is proposed, which overcomes the disadvantages of direct V1V relative posing methods and can work effectively and improve localization accuracy, especially for heterogeneous vehicle systems.
Abstract: Vehicle localization (ground vehicles) is a fundamental task for intelligent vehicle systems; this paper deals with the issue of multi-vehicle cooperative localization which can bring performance improvement over traditional single vehicle localization. To tackle the problem of vehicle-to-vehicle (V2V) relative pose estimation that is essential for realizing cooperative localization, an indirect V2V relative pose estimation (InDV2VRPE) method is proposed, which overcomes the disadvantages of direct V2V relative pose estimation methods. As part of this InDV2VRPE method, a new map merging method is described. Cooperative localization is realized using this InDV2VRPE method. Real-data experiments demonstrate that the proposed cooperative localization method can work effectively and improve localization accuracy, especially for heterogeneous vehicle systems.

41 citations

Journal ArticleDOI
15 Dec 2015-Wear
TL;DR: In this article, the effect of inertia and strain rate sensitivity of three materials under cavitation hydrodynamic impact has been studied in details by using finite element simulations, and it is found that if the impact duration is very short compared to a characteristic time of the material based on its natural frequency, no pit would form into the material even if a high impact stress is very high.

41 citations

Journal ArticleDOI
TL;DR: Intranuclear aggregation and cytoplasmic mislocalization of mutant FOXL2 may be considered as loose predictors of ovarian dysfunction and a first step towards circumventing the lack of a clear-cut genotype-phenotype correlation in BPES.
Abstract: Mutations of FOXL2 are responsible for the Blepharophimosis-Ptotsis-Epicantus-inversus Syndrome (BPES), involving complex eyelid malformations often associated with premature ovarian failure (POF). Loss-of-function mutations are expected to lead to BPES associated with POF, whereas hypomorphic mutations would lead to BPES without ovarian dysfunction. However, multiple exceptions to the genotype-phenotype correlation have been described and missense mutations in the forkhead domain can lead to either type of BPES. This renders almost impossible the prediction of a POF condition from a given genotype. Moreover, no clear-cut correlation between nuclear and/or cytoplasmic aggregation or cytoplasmic retention of mutant FOXL2 forms and the BPES type has been established thus far. Here, we dissect the molecular and functional effects of 10 FOXL2 mutants, known to induce BPES associated with POF or not. We found a correlation between the transcriptional activity of FOXL2 variants on two different reporter promoters and the type of BPES. We used this functional classification framework to explore the behavior of 18 missense mutations leading to BPES of unknown type. The reporters used enabled us to assess the risk of POF associated with these mutations. Moreover, we document a previously overlooked correlation between subcellular mislocalization and aggregation of mutant FOXL2 and the type of BPES, known or predicted using our reporter assays. Thus, intranuclear aggregation and cytoplasmic mislocalization of mutant FOXL2 may be considered as loose predictors of ovarian dysfunction. The functional classification tool described here is a first step towards circumventing the lack of a clear-cut genotype-phenotype correlation in BPES.

41 citations


Authors

Showing all 1899 results

NameH-indexPapersCitations
Mathias Fink11690051759
George G. Malliaras9438228533
Mickael Tanter8558329452
Gerard Mourou8265334147
Catherine Lapierre7922718286
Carlo Adamo7544436092
Jean-François Joanny7229420700
Marie-Paule Lefranc7238121087
Paul B. Rainey7022217930
Vincent Lepetit7026826207
Bernard Asselain6940923648
Michael J. Baker6939420834
Jacques Prost6819819064
Jean-Philippe Vert6723517593
Jacques Mairesse6631020539
Network Information
Related Institutions (5)
Royal Institute of Technology
68.4K papers, 1.9M citations

91% related

École Normale Supérieure
99.4K papers, 3M citations

90% related

RWTH Aachen University
96.2K papers, 2.5M citations

89% related

Eindhoven University of Technology
52.9K papers, 1.5M citations

89% related

École Polytechnique Fédérale de Lausanne
98.2K papers, 4.3M citations

89% related

Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20239
202212
202174
202093
2019127
2018145