Paul Sabatier University

About: Paul Sabatier University is a education organization based out in Toulouse, France. It is known for research contribution in the topics: Population & Adipose tissue. The organization has 15431 authors who have published 23386 publications receiving 858364 citations.

Genotypic and Phenotypic Analysis of Enterobacter sakazakii Strains from an Outbreak Resulting in Fatalities in a Neonatal Intensive Care Unit in France

Abstract: In 1994, an outbreak of Enterobacter sakazakii infections occurred in a neonatal intensive care unit in France from 5 May to 11 July. During the outbreak, 13 neonates were infected with E. sakazakii, resulting in 3 deaths. In addition, four symptomless neonates were colonized by E. sakazakii. The strains were subjected to 16S rRNA gene sequence analysis, genotyped using pulsed-field gel electrophoresis, and phenotyped for a range of enzyme activities. E. sakazakii was isolated from various anatomical sites, reconstituted formula, and an unopened can of powdered infant formula. A fourth neonate died from septic shock, attributed to E. sakazakii infection, during this period. However, 16S rRNA gene sequence analysis revealed that the organism was Enterobacter cloacae. There were three pulsotypes of E. sakazakii associated with infected neonates, and three neonates were infected by more than one genotype. One genotype matched isolates from unused prepared formula and unfinished formula. However, no pulsotypes matched the E. sakazakii strain recovered from an unopened can of powdered infant formula. One pulsotype was associated with the three fatal cases, and two of these isolates had extended-spectrum beta-lactamase activity. It is possible that E. sakazakii strains differ in their pathogenicities, as shown by the range of symptoms associated with each pulsotype.

Quantum Moment Hydrodynamics and the Entropy Principle

Abstract: This paper presents how a non-commutative version of the entropy extremalization principle allows to construct new quantum hydrodynamic models. Our starting point is the moment method, which consists in integrating the quantum Liouville equation with respect to momentum p against a given vector of monomials of p. Like in the classical case, the so-obtained moment system is not closed. Inspired from Levermore's procedure in the classical case,(26) we propose to close the moment system by a quantum (Wigner) distribution function which minimizes the entropy subject to the constraint that its moments are given. In contrast to the classical case, the quantum entropy is defined globally (and not locally) as the trace of an operator. Therefore, the relation between the moments and the Lagrange multipliers of the constrained entropy minimization problem becomes nonlocal and the resulting moment system involves nonlocal operators (instead of purely local ones in the classical case). In the present paper, we discuss some practical aspects and consequences of this nonlocal feature.

Numerical Simulation of the Smoluchowski Coagulation Equation

Abstract: In this paper, we develop a numerical scheme for the Smoluchowski coagulation equation, which relies on a conservative formulation and a finite volume approach. Several numerical simulations are performed to test the validity of the scheme and the expected behavior of the model. In particular the gelation phenomenon and the long time behavior of the solution are numerically studied.