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Institution

Paul Sabatier University

EducationToulouse, France
About: Paul Sabatier University is a education organization based out in Toulouse, France. It is known for research contribution in the topics: Population & Adipose tissue. The organization has 15431 authors who have published 23386 publications receiving 858364 citations.


Papers
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Journal ArticleDOI
TL;DR: In this paper, the authors present an improvement of previous techniques to determine critical flux in ultrafiltration, which allows having accurate values of the critical flux and the rate of irreversibility of the created deposit on the membrane.

166 citations

Journal ArticleDOI
TL;DR: Sourdough was demonstrated to be a very attractive biotope for the isolation of lactic acid bacteria producing novel polymers which could find interesting applications such as texturing agent or prebiotics.
Abstract: The distribution and diversity of natural exopolysaccharides (EPS) produced from sucrose by thirty heterofermentative lactic acid bacteria strains from French traditional sourdoughs was investigated. The EPS production was found to be related to glucansucrase and fructansucrase extracellular activities. Depending on the strain, soluble and/or cell-associated glycansucrases were secreted. Structural characterization of the polymers by 1H and 13C NMR spectroscopy analysis further demonstrated a high diversity of EPS structures. Notably, we detected strains that synthesize glucans showing amazing variations in the amount of alpha-(1-->2), alpha-(1-->3) and alpha-(1-->6) linkages. The representation of Leuconostoc strains which produce putative alternan polymers and alpha-(1-->2) branched polymers was particularly high. The existence of glucan- and fructansucrase encoding genes was also confirmed by PCR detection. Sourdough was thus demonstrated to be a very attractive biotope for the isolation of lactic acid bacteria producing novel polymers which could find interesting applications such as texturing agent or prebiotics.

166 citations

Book
01 Jun 2015
TL;DR: It is argued that rapid object categorizations in natural scenes can be done without focused attention and are most likely based on coarse and unconscious visual representations activated with the first available (magnocellular) visual information.
Abstract: Visual categorization appears both effortless and virtually instantaneous, the study by Thorpe et al. (1996) was the first to estimate the processing time necessary to perform fast visual categorization of animals in briefly flashed (20ms) natural photographs. They observed a large differential EEG activity between target and distrater correct trials that developed from 150 ms after stimulus onset. A value that was later shown to be even shorter in monkeys! With such strong processing time constraints, it was difficult to escape the conclusion that rapid visual categorization was relying on massively parallel, essentially feed-forward processing of visual information. Since 1996, we have conducted a large number of studies to determine the characteristics and limits of fast visual categorization. The present chapter will review some of the main results obtained. I will argue that rapid object categorizations in natural scenes can be done without focused attention and are most likely based on coarse and unconscious visual representations activated with the first available (magnocellular) visual information. Fast visual processing proved efficient for the categorization of large superordinate object or scene categories, but shows its limits when more detailed basic representations are required. Basic objects (dogs, cars) or scenes (mountain or sea landscapes) representations need additionnal processing time to be activated. A finding that is at odds with the widely accepted idea that such basic representations are at the entry level of the system. Interestingly, focused attention is still not required to perform such, more time consuming, basic categorizations. Finally we will show that object and context processing can interact very early in an ascending wave of visual information processing. We will discuss how such data could result from our experience with a highly structured and predictable surrounding world that shaped neuronal visual selectivity.

166 citations

Journal ArticleDOI
TL;DR: The immunological conflict between ACPA and fibrin could sustain synovial inflammation not only via pro‐inflammatory effector mechanisms but also via impairment of fibrinolysis.
Abstract: Formation of the epitopes recognized by the rheumatoid arthritis (RA)-specific autoantibodies to citrullinated proteins (ACPA) on filaggrin and on the alpha- and beta-chains of fibrin, their synovial target, requires conversion of their arginyl residues into citrullyl residues, but is also affected by their amino-acyl environment. Using competition with five citrullinated filaggrin-derived peptides bearing major ACPA epitopes, we confirmed the close cross-reactivity between filaggrin and citrullinated fibrin. To identify the sequential epitopes recognized on fibrin by ACPA, 71 citrullinated 15-mer peptides derived from all the sites of the alpha- and beta-chains of fibrin harboring arginyl residues were tested by ELISA using ACPA-positive RA sera exhibiting different reactivity profiles to the five filaggrin peptides. We identified 18 fibrin-derived peptides bearing ACPA epitopes. Regarding the ability of fibrinogen arginyl residues to be citrullinated in vitro, 11 of the peptides likely correspond to in vivo targeted epitopes. Two out of them bear major epitopes and are located in the central globular domain of the protein. In the synovial tissue, fibrin citrullination and ACPA binding could impair fibrin degradation by plasmin. The immunological conflict between ACPA and fibrin could therefore sustain synovial inflammation not only via pro-inflammatory effector mechanisms but also via impairment of fibrinolysis.

166 citations

Journal ArticleDOI
TL;DR: In this article, the correlation between capacitance and pore size in electrical double-layer capacitors (EDLCs), also known as supercapacitors or ultracapacitors, is clarified.
Abstract: This Viewpoint clarifies the correlation between capacitance and pore size in electrical double-layer capacitors (EDLCs, also known as supercapacitors or ultracapacitors), which is of high practical importance for the design of advanced carbon electrode materials. Two extreme cases are obvious: excessively large pores, accompanied by large pore volumes and limited specific surface area, will lead to a low energy storage capacity, whereas very small pores will limit the ion access due to steric effects, in addition to imposing obstacles to ion transport

166 citations


Authors

Showing all 15486 results

NameH-indexPapersCitations
Yury Gogotsi171956144520
Tobin J. Marks1591621111604
L. Montier13840397094
Jean-Paul Kneib13880589287
Olivier Forni13754895819
J. Aumont13129995006
Julian I. Schroeder12031550323
Bruno Vellas118101170667
Christopher G. Goetz11665159510
Didier Dubois11374254741
Alain Dufresne11135845904
Henri Prade10891754583
Louis Bernatchez10656835682
Walter Wahli10536549372
Patrice D. Cani10037049523
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202332
202293
2021759
2020753
2019728
2018622