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Institution

Pierre-and-Marie-Curie University

EducationParis, France
About: Pierre-and-Marie-Curie University is a education organization based out in Paris, France. It is known for research contribution in the topics: Population & Raman spectroscopy. The organization has 34448 authors who have published 56139 publications receiving 2392398 citations.


Papers
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Journal ArticleDOI
TL;DR: The safety profile was poor and patients with platelet count ≤ 100,000/mm(3) and serum albumin <35 g/L should not be treated with the triple therapy, and the on-treatment virological response was high.

431 citations

Journal ArticleDOI
TL;DR: In this paper, a parametrization of the deuteron wave function calculated with the Paris potential is presented, in both configuration and momentum spaces, for the case where the wave function is assumed to have the same momentum.

431 citations

Journal ArticleDOI
20 Aug 2010-Science
TL;DR: The coupling of actin cables to the nuclear membrane for nuclear movement via specific membrane proteins indicates that, like plasma membrane integrins, nuclear membrane proteins assemble into actin-dependent arrays for force transduction.
Abstract: Nuclei move to specific locations to polarize migrating and differentiating cells. Many nuclear movements are microtubule-dependent. However, nuclear movement to reorient the centrosome in migrating fibroblasts occurs through an unknown actin-dependent mechanism. We found that linear arrays of outer (nesprin2G) and inner (SUN2) nuclear membrane proteins assembled on and moved with retrogradely moving dorsal actin cables during nuclear movement in polarizing fibroblasts. Inhibition of nesprin2G, SUN2, or actin prevented nuclear movement and centrosome reorientation. The coupling of actin cables to the nuclear membrane for nuclear movement via specific membrane proteins indicates that, like plasma membrane integrins, nuclear membrane proteins assemble into actin-dependent arrays for force transduction.

431 citations

Journal ArticleDOI
TL;DR: In this article, a likelihood-based method for measuring weak gravitational lensing shear in deep galaxy surveys is described and applied to the Canada-France-Hawaii Telescope (CFHT) Lensing Survey.
Abstract: A likelihood-based method for measuring weak gravitational lensing shear in deep galaxy surveys is described and applied to the Canada–France–Hawaii Telescope (CFHT) Lensing Survey (CFHTLenS) CFHTLenS comprises 154 deg^2 of multi-colour optical data from the CFHT Legacy Survey, with lensing measurements being made in the i′ band to a depth i′_(AB) < 247, for galaxies with signal-to-noise ratio ν_(SN) ≳ 10 The method is based on the lensfit algorithm described in earlier papers, but here we describe a full analysis pipeline that takes into account the properties of real surveys The method creates pixel-based models of the varying point spread function (PSF) in individual image exposures It fits PSF-convolved two-component (disc plus bulge) models to measure the ellipticity of each galaxy, with Bayesian marginalization over model nuisance parameters of galaxy position, size, brightness and bulge fraction The method allows optimal joint measurement of multiple, dithered image exposures, taking into account imaging distortion and the alignment of the multiple measurements We discuss the effects of noise bias on the likelihood distribution of galaxy ellipticity Two sets of image simulations that mirror the observed properties of CFHTLenS have been created to establish the method's accuracy and to derive an empirical correction for the effects of noise bias

430 citations

Journal ArticleDOI
16 Mar 2007-Science
TL;DR: Aerosols and ozone could be perturbing the radiative budget of the Arctic through processes specific to the region: Absorption of solar radiation by aerosols is enhanced by highly reflective snow and ice surfaces; deposition of light- absorption aerosols on snow or ice can decrease surface albedo; and tropospheric ozone forcing may also be contributing to warming in this region.
Abstract: Notable warming trends have been observed in the Arctic. Although increased human-induced emissions of long-lived greenhouse gases are certainly the main driving factor, air pollutants, such as aerosols and ozone, are also important. Air pollutants are transported to the Arctic, primarily from Eurasia, leading to high concentrations in winter and spring (Arctic haze). Local ship emissions and summertime boreal forest fires may also be important pollution sources. Aerosols and ozone could be perturbing the radiative budget of the Arctic through processes specific to the region: Absorption of solar radiation by aerosols is enhanced by highly reflective snow and ice surfaces; deposition of light-absorbing aerosols on snow or ice can decrease surface albedo; and tropospheric ozone forcing may also be contributing to warming in this region. Future increases in pollutant emissions locally or in mid-latitudes could further accelerate global warming in the Arctic.

430 citations


Authors

Showing all 34671 results

NameH-indexPapersCitations
Zhong Lin Wang2452529259003
Guido Kroemer2361404246571
Krzysztof Matyjaszewski1691431128585
J. E. Brau1621949157675
E. Hivon147403118440
Kazuhiko Hara1411956107697
Simon Prunet14143496314
H. J. McCracken14057971091
G. Calderini1391734102408
Stefano Giagu1391651101569
Jean-Paul Kneib13880589287
G. Marchiori137159094277
J. Ocariz136156295905
Jean-Marie Tarascon136853137673
Alexis Brice13587083466
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20241
202370
2022361
2021388
2020580
2019855