Institution
Pierre-and-Marie-Curie University
Education•Paris, France•
About: Pierre-and-Marie-Curie University is a education organization based out in Paris, France. It is known for research contribution in the topics: Population & Raman spectroscopy. The organization has 34448 authors who have published 56139 publications receiving 2392398 citations.
Topics: Population, Raman spectroscopy, Catalysis, Context (language use), Gene
Papers published on a yearly basis
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TL;DR: The PRESERVE score might help ICU physicians select appropriate candidates for ECMO among severe ARDS patients and future studies should also focus on physical and psychosocial rehabilitation that could lead to improved HRQL in this population.
Abstract: Purpose
This study was designed to identify factors associated with death by 6 months post-intensive care unit (ICU) discharge and to develop a practical mortality risk score for extracorporeal membrane oxygenation (ECMO)-treated acute respiratory distress syndrome (ARDS) patients. We also assessed long-term survivors’ health-related quality of life (HRQL), respiratory symptoms, and anxiety, depression and post-traumatic stress disorder (PTSD) frequencies.
430 citations
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Geophysical Fluid Dynamics Laboratory1, Lancaster University2, Forschungszentrum Jülich3, Cornell University4, Pierre-and-Marie-Curie University5, Centre national de la recherche scientifique6, University of Edinburgh7, Met Office8, Goddard Institute for Space Studies9, National Institute of Water and Atmospheric Research10, University of Cambridge11, Gordon and Betty Moore Foundation12, Lawrence Livermore National Laboratory13, École Polytechnique Fédérale de Lausanne14, University of Iowa15, University of Maryland, Baltimore County16, University of Oslo17, Environment Canada18, European Science Foundation19, University of Wisconsin-Madison20, Harvard University21, Norwegian Meteorological Institute22, York University23, United States Environmental Protection Agency24, University of L'Aquila25, Seoul National University26, Max Planck Society27, Northrop Grumman Corporation28, Michigan Technological University29
TL;DR: In this article, an ensemble of 21 global and hemispheric chemical transport models is used to estimate the spatial average surface ozone (O-3) response over east Asia (EA), Europe (EU), North America (NA), and south Asia (SA) to 20% decreases in anthropogenic emissions of the O-3 precursors, NOx, NMVOC, and CO.
Abstract: Understanding the surface O-3 response over a "receptor" region to emission changes over a foreign "source" region is key to evaluating the potential gains from an international approach to abate ozone (O-3) pollution. We apply an ensemble of 21 global and hemispheric chemical transport models to estimate the spatial average surface O-3 response over east Asia (EA), Europe (EU), North America (NA), and south Asia (SA) to 20% decreases in anthropogenic emissions of the O-3 precursors, NOx, NMVOC, and CO (individually and combined), from each of these regions. We find that the ensemble mean surface O-3 concentrations in the base case (year 2001) simulation matches available observations throughout the year over EU but overestimates them by > 10 ppb during summer and early fall over the eastern United States and Japan. The sum of the O-3 responses to NOx, CO, and NMVOC decreases separately is approximately equal to that from a simultaneous reduction of all precursors. We define a continental-scale "import sensitivity" as the ratio of the O-3 response to the 20% reductions in foreign versus "domestic" (i.e., over the source region itself) emissions. For example, the combined reduction of emissions from the three foreign regions produces an ensemble spatial mean decrease of 0.6 ppb over EU (0.4 ppb from NA), less than the 0.8 ppb from the reduction of EU emissions, leading to an import sensitivity ratio of 0.7. The ensemble mean surface O-3 response to foreign emissions is largest in spring and late fall (0.7-0.9 ppb decrease in all regions from the combined precursor reductions in the three foreign regions), with import sensitivities ranging from 0.5 to 1.1 (responses to domestic emission reductions are 0.8-1.6 ppb). High O-3 values are much more sensitive to domestic emissions than to foreign emissions, as indicated by lower import sensitivities of 0.2 to 0.3 during July in EA, EU, and NA when O-3 levels are typically highest and by the weaker relative response of annual incidences of daily maximum 8-h average O-3 above 60 ppb to emission reductions in a foreign region(< 10-20% of that to domestic) as compared to the annual mean response (up to 50% of that to domestic). Applying the ensemble annual mean results to changes in anthropogenic emissions from 1996 to 2002, we estimate a Northern Hemispheric increase in background surface O-3 of about 0.1 ppb a(-1), at the low end of the 0.1-0.5 ppb a(-1) derived from observations. From an additional simulation in which global atmospheric methane was reduced, we infer that 20% reductions in anthropogenic methane emissions from a foreign source region would yield an O-3 response in a receptor region that roughly equals that produced by combined 20% reductions of anthropogenic NOx, NMVOC, and CO emissions from the foreign source
430 citations
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California State University San Marcos1, Alfred Wegener Institute for Polar and Marine Research2, University of Alberta3, United States Department of Energy4, J. Craig Venter Institute5, Institut national de la recherche agronomique6, Ruhr University Bochum7, University of Maryland, College Park8, Monterey Bay Aquarium Research Institute9, University College London10, Centre national de la recherche scientifique11, Harvard University12, Ghent University13, Rothamsted Research14, Pierre-and-Marie-Curie University15, University of Essex16, Pontifical Catholic University of Chile17, Plymouth Marine Laboratory18, Columbia University19, Woods Hole Oceanographic Institution20, University of Cologne21, Natural History Museum22, Rutgers University23, Georgia Institute of Technology24, Moscow Institute of Physics and Technology25, University of Ostrava26, National Institutes of Health27, University of Nebraska Medical Center28, University of Southampton29, Oregon State University30, Dalhousie University31, University of Texas Health Science Center at Houston32, University of East Anglia33, University of Potsdam34, University of Bergen35, University of Washington36, University of Freiburg37, University of Marburg38, University of Los Andes39, Bigelow Laboratory For Ocean Sciences40, University of Exeter41, Oak Ridge National Laboratory42, California State University, Chico43, University of Tsukuba44
TL;DR: Comparisons across strains demonstrate that E. huxleyi, which has long been considered a single species, harbours extensive genome variability reflected in different metabolic repertoires, and reveals a pan genome (core genes plus genes distributed variably between strains) probably supported by an atypical complement of repetitive sequence in the genome.
Abstract: Coccolithophores have influenced the global climate for over 200 million years(1). These marine phytoplankton can account for 20 per cent of total carbon fixation in some systems(2). They form blooms that can occupy hundreds of thousands of square kilometres and are distinguished by their elegantly sculpted calcium carbonate exoskeletons (coccoliths), rendering them visible from space(3). Although coccolithophores export carbon in the form of organic matter and calcite to the sea floor, they also release CO2 in the calcification process. Hence, they have a complex influence on the carbon cycle, driving either CO2 production or uptake, sequestration and export to the deep ocean(4). Here we report the first haptophyte reference genome, from the coccolithophore Emiliania huxleyi strain CCMP1516, and sequences from 13 additional isolates. Our analyses reveal a pan genome (core genes plus genes distributed variably between strains) probably supported by an atypical complement of repetitive sequence in the genome. Comparisons across strains demonstrate that E. huxleyi, which has long been considered a single species, harbours extensive genome variability reflected in different metabolic repertoires. Genome variability within this species complex seems to underpin its capacity both to thrive in habitats ranging from the equator to the subarctic and to form large-scale episodic blooms under a wide variety of environmental conditions.
430 citations
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TL;DR: The identification of rod-derived cone viability factor is a truncated thioredoxin-like protein specifically expressed by photoreceptors that offers new treatment possibilities for retinitis pigmentosa.
Abstract: Retinitis pigmentosa is an untreatable, inherited retinal disease that leads to blindness. The disease initiates with the loss of night vision due to rod photoreceptor degeneration, followed by irreversible, progressive loss of cone photoreceptor. Cone loss is responsible for the main visual handicap, as cones are essential for day and high-acuity vision. Their loss is indirect, as most genes associated with retinitis pigmentosa are not expressed by these cells. We previously showed that factors secreted from rods are essential for cone viability. Here we identified one such trophic factor by expression cloning and named it rod-derived cone viability factor (RdCVF). RdCVF is a truncated thioredoxin-like protein specifically expressed by photoreceptors. The identification of this protein offers new treatment possibilities for retinitis pigmentosa.
429 citations
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TL;DR: In this article, the role of hexacyanoferrate vacancies in photo-induced magnetization is pointed out, and three compounds with a variable cobalt environment are synthesized to point out the conditions required to observe the photoinduced magnetisation.
Abstract: Photoinduced magnetization has been recently evidenced by Hashimoto et al. in CoFe Prussian blue analogues. We synthesized three compounds with a variable cobalt environment to point out the conditions required to observe the photoinduced magnetization. Structure and electronic structure of the compounds have been investigated combining XANES, infrared spectroscopy, and powder X-ray diffraction experiments. Magnetization as a function of temperature before and after irradiation showed that diamagnetic pairs CoIII−NC−FeII are necessary for the existence of the photoinduced magnetization, but their presence is not a sufficient condition. The role of hexacyanoferrate vacancies in the phenomenon is pointed out.
429 citations
Authors
Showing all 34671 results
Name | H-index | Papers | Citations |
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Zhong Lin Wang | 245 | 2529 | 259003 |
Guido Kroemer | 236 | 1404 | 246571 |
Krzysztof Matyjaszewski | 169 | 1431 | 128585 |
J. E. Brau | 162 | 1949 | 157675 |
E. Hivon | 147 | 403 | 118440 |
Kazuhiko Hara | 141 | 1956 | 107697 |
Simon Prunet | 141 | 434 | 96314 |
H. J. McCracken | 140 | 579 | 71091 |
G. Calderini | 139 | 1734 | 102408 |
Stefano Giagu | 139 | 1651 | 101569 |
Jean-Paul Kneib | 138 | 805 | 89287 |
G. Marchiori | 137 | 1590 | 94277 |
J. Ocariz | 136 | 1562 | 95905 |
Jean-Marie Tarascon | 136 | 853 | 137673 |
Alexis Brice | 135 | 870 | 83466 |