Institution
Pierre-and-Marie-Curie University
Education•Paris, France•
About: Pierre-and-Marie-Curie University is a education organization based out in Paris, France. It is known for research contribution in the topics: Population & Raman spectroscopy. The organization has 34448 authors who have published 56139 publications receiving 2392398 citations.
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Albert Einstein Institution1, Ewha Womans University2, University of Oxford3, Hungarian Academy of Sciences4, CERN5, University of Savoy6, Uppsala University7, Petersburg Nuclear Physics Institute8, King's College London9, Jagiellonian University10, Pierre-and-Marie-Curie University11, École Normale Supérieure12, Princeton University13, University of Copenhagen14, University of Lyon15, University of Miami16, Imperial College London17, Pennsylvania State University18, University of California, Santa Barbara19, Humboldt University of Berlin20, Utrecht University21, University of York22, Perimeter Institute for Theoretical Physics23
TL;DR: In this article, the authors present an overview of the achievements and the status of integrability in the context of the AdS/CFT correspondence as of the year 2010.
Abstract: This is the introductory chapter of a review collection on integrability in the context of the AdS/CFT correspondence. In the collection we present an overview of the achievements and the status of this subject as of the year 2010.
1,564 citations
Panos Deloukas1, Stavroula Kanoni1, Christina Willenborg2, Martin Farrall3 +201 more•Institutions (64)
TL;DR: An association analysis in CAD cases and controls identifies 15 loci reaching genome-wide significance, taking the number of susceptibility loci for CAD to 46, and a further 104 independent variants strongly associated with CAD at a 5% false discovery rate (FDR).
Abstract: Coronary artery disease (CAD) is the commonest cause of death. Here, we report an association analysis in 63,746 CAD cases and 130,681 controls identifying 15 loci reaching genome-wide significance, taking the number of susceptibility loci for CAD to 46, and a further 104 independent variants (r(2) < 0.2) strongly associated with CAD at a 5% false discovery rate (FDR). Together, these variants explain approximately 10.6% of CAD heritability. Of the 46 genome-wide significant lead SNPs, 12 show a significant association with a lipid trait, and 5 show a significant association with blood pressure, but none is significantly associated with diabetes. Network analysis with 233 candidate genes (loci at 10% FDR) generated 5 interaction networks comprising 85% of these putative genes involved in CAD. The four most significant pathways mapping to these networks are linked to lipid metabolism and inflammation, underscoring the causal role of these activities in the genetic etiology of CAD. Our study provides insights into the genetic basis of CAD and identifies key biological pathways.
1,518 citations
Valentina Escott-Price1, Céline Bellenguez2, Li-San Wang3, Seung Hoan Choi4 +191 more•Institutions (67)
TL;DR: The additional genes identified in this study, have an array of functions previously implicated in Alzheimer's disease, including aspects of energy metabolism, protein degradation and the immune system and add further weight to these pathways as potential therapeutic targets in Alzheimers disease.
Abstract: Background: Alzheimer's disease is a common debilitating dementia with known heritability, for which 20 late onset susceptibility loci have been identified, but more remain to be discovered. This s ...
1,518 citations
National Oceanography Centre, Southampton1, Stanford University2, Bar-Ilan University3, Centre national de la recherche scientifique4, University of Otago5, University of Tasmania6, McGill University7, University of Essex8, Pierre-and-Marie-Curie University9, ETH Zurich10, University of East Anglia11, University of Exeter12, Cornell University13, University of Vigo14, University of Pennsylvania15, University of California, Irvine16, Nagoya University17, Leibniz Institute of Marine Sciences18, Woods Hole Oceanographic Institution19, University of Bergen20, University of Tokyo21, University of Concepción22
TL;DR: In this paper, the authors reveal two broad regimes of phytoplankton nutrient limitation in the modern upper ocean: Nitrogen availability tends to limit productivity throughout much of the surface low-latitude ocean, where the supply of nutrients from the subsurface is relatively slow.
Abstract: Microbial activity is a fundamental component of oceanic nutrient cycles. Photosynthetic microbes, collectively termed phytoplankton, are responsible for the vast majority of primary production in marine waters. The availability of nutrients in the upper ocean frequently limits the activity and abundance of these organisms. Experimental data have revealed two broad regimes of phytoplankton nutrient limitation in the modern upper ocean. Nitrogen availability tends to limit productivity throughout much of the surface low-latitude ocean, where the supply of nutrients from the subsurface is relatively slow. In contrast, iron often limits productivity where subsurface nutrient supply is enhanced, including within the main oceanic upwelling regions of the Southern Ocean and the eastern equatorial Pacific. Phosphorus, vitamins and micronutrients other than iron may also (co-)limit marine phytoplankton. The spatial patterns and importance of co-limitation, however, remain unclear. Variability in the stoichiometries of nutrient supply and biological demand are key determinants of oceanic nutrient limitation. Deciphering the mechanisms that underpin this variability, and the consequences for marine microbes, will be a challenge. But such knowledge will be crucial for accurately predicting the consequences of ongoing anthropogenic perturbations to oceanic nutrient biogeochemistry.
1,516 citations
TL;DR: A theory for the ab initio calculation of all-electron NMR chemical shifts in insulators using pseudopotentials is presented in this article, which is formulated for both finite and infinitely periodic systems and is based on an extension to the projector augmented-wave approach of Bl\"ochl [P. E. Blachl, Phys. Rev. B 50, 17 953 (1994)] and the method of Mauri et al.
Abstract: A theory for the ab initio calculation of all-electron NMR chemical shifts in insulators using pseudopotentials is presented. It is formulated for both finite and infinitely periodic systems and is based on an extension to the projector augmented-wave approach of Bl\"ochl [P. E. Bl\"ochl, Phys. Rev. B 50, 17 953 (1994)] and the method of Mauri et al. [F. Mauri, B. G. Pfrommer, and S. G. Louie, Phys. Rev. Lett. 77, 5300 (1996)]. The theory is successfully validated for molecules by comparison with a selection of quantum chemical results, and in periodic systems by comparison with plane-wave all-electron results for diamond.
1,516 citations
Authors
Showing all 34671 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Zhong Lin Wang | 245 | 2529 | 259003 |
| Guido Kroemer | 236 | 1404 | 246571 |
| Krzysztof Matyjaszewski | 169 | 1431 | 128585 |
| J. E. Brau | 162 | 1949 | 157675 |
| E. Hivon | 147 | 403 | 118440 |
| Kazuhiko Hara | 141 | 1956 | 107697 |
| Simon Prunet | 141 | 434 | 96314 |
| H. J. McCracken | 140 | 579 | 71091 |
| G. Calderini | 139 | 1734 | 102408 |
| Stefano Giagu | 139 | 1651 | 101569 |
| Jean-Paul Kneib | 138 | 805 | 89287 |
| G. Marchiori | 137 | 1590 | 94277 |
| J. Ocariz | 136 | 1562 | 95905 |
| Jean-Marie Tarascon | 136 | 853 | 137673 |
| Alexis Brice | 135 | 870 | 83466 |