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Showing papers by "Polytechnic University of Milan published in 2004"


Journal ArticleDOI
TL;DR: In this article, a detailed investigation of electronic switching in chalcogenide-based phase-change memory devices is presented, and a physical picture of the switching mechanism is proposed.
Abstract: A detailed investigation of electronic switching in chalcogenide-based phase-change memory devices is presented. An original bandgap model consistent with the microscopic structure of both crystalline and amorphous chalcogenide is described, and a physical picture of the switching mechanism is proposed. Numerical simulations provide, for the first time, a quantitative description of the peculiar current-voltage curve of a Ge/sub 2/Sb/sub 2/Te/sub 5/ resistor, in good agreement with measurements performed on test devices.

586 citations


Journal ArticleDOI
TL;DR: In this article, the authors provide a general theoretical framework exploiting copulas for studying the return periods of hydrological events; in particular, they consider events depending upon the joint behavior of two nonindependent random variables, an approach which can easily be generalized to the multivariate case.
Abstract: [1] In this paper we provide a general theoretical framework exploiting copulas for studying the return periods of hydrological events; in particular, we consider events depending upon the joint behavior of two nonindependent random variables, an approach which can easily be generalized to the multivariate case. We show that using copulas may greatly simplify the calculations and may even yield analytical expressions for the isolines of the return periods, both in the unconditional and in the conditional case. In addition, we show how a new probability distribution may be associated with the return period of specific events and introduce the definitions of sub-, super-, and critical events as well as those of primary and secondary return periods. An illustration of the techniques proposed is provided by analyzing some case studies already examined in literature.

526 citations


Journal ArticleDOI
TL;DR: There are at least two rhythms below 50 Hz that are separately modulated by antiparkinsonian medication: one at low frequencies and one in the beta range, consistent with the hypothesis of multiple oscillating systems.

490 citations


Journal ArticleDOI
TL;DR: In this article, the evolution of the structural behavior in reinforced concrete beams subjected to reinforcement corrosion is studied by developing a suitable numerical procedure, which is validated by comparison with available test data.
Abstract: The evolution of the structural behavior in reinforced concrete beams subjected to reinforcement corrosion is studied here, by developing a suitable numerical procedure, which is validated by comparison with available test data. There are two objectives of this study: The understanding of the many aspects of the progressive damage in an existing structure (cracking and crushing, bar yielding, bond failure), and the assessment of the actual safety level. Nonlinear finite element analysis is used; the effects of corrosion are modeled by reducing the geometry of the finite elements representing separately the steel bars and the concrete, and by modifying the constitutive laws of the materials (steel and concrete) and of their interface (bond). Both the service and ultimate limit states are studied, showing the importance of the following phenomena: (1) Stiffness decay because of impaired tension stiffening, (2) crack pattern evolution accompanied by enhanced shear effects, (3) strength deterioration in bendi...

489 citations


Journal ArticleDOI
S. Amerio1, Salvatore Amoruso, M. Antonello, P. Aprili, Mario Armenante, F. Arneodo, A. Badertscher, B. Baiboussinov1, M. Baldo Ceolin1, G. Battistoni2, B. Bekman3, P. Benetti4, Elisa Bernardini, M. Bischofberger, A. Borio di Tigliole4, R. Brunetti4, Riccardo Bruzzese, Antonio Bueno5, E. Calligarich4, Mario Campanelli, F. Carbonara, C. Carpanese, D. Cavalli2, F. Cavanna, P. Cennini6, S. Centro1, A. Cesana2, A. Cesana7, Chang Chen8, D. Chen8, D.B. Chen1, Yi-Chun Chen8, Rosalía Cid5, David B. Cline9, K. Cieślik, A. G. Cocco, D. Corti1, Z. Dai, C. De Vecchi4, A. Dabrowska, A. Di Cicco, R. Dolfini4, Antonio Ereditato, Marta Felcini, A. D. Ferella, Arnaud Ferrari6, Arnaud Ferrari2, Federico Ferri, G. Fiorillo, S. Galli, D. García Gámez5, Y. Ge, D. Gibin1, A. Gigli Berzolari4, I. Gil-Botella, Krzysztof M. Graczyk, L. Grandi4, A. Guglielmi1, K. He8, J. Holeczek3, Xiaojing Huang8, Cezary Juszczak, D. Kielczewska10, Jan Kisiel3, T. Kozłowski, H. Kuna-Ciskal, M. Laffranchi, J. Łagoda10, Z. Li8, B. Lisowski9, F. Lu8, J. Ma8, Gianpiero Mangano, G. Mannocchi, M. Markiewicz, A. Martinez de la Ossa5, C. Matthey9, F. Mauri4, D. Mazza, A. Melgarejo5, Alessandro Menegolli4, G. Meng1, M. Messina, Jerzy W. Mietelski, C. Montanari4, Silvia Muraro2, S. Navas-Concha5, M. Nicoletto1, J. A. Nowak, G. Nurzia, C. Osuna5, S. Otwinowski9, Q. Ouyang8, O. Palamara, D. Pascoli1, L. Periale, G. Piano Mortari, A. Piazzoli4, P. Picchi11, F. Pietropaolo1, W. Półchłopek, M. C. Prata4, T. Rancati2, A. Rappoldi4, G.L. Raselli4, J. Rico, E. Rondio, Massimo Rossella4, André Rubbia, C. Rubbia4, Paola Sala2, R. Santorelli, D. A. Scannicchio4, E. Segreto, Youngho Seo9, F. Sergiampietri9, Jan T. Sobczyk, N. Spinelli, J. Stepaniak, R. Sulej12, M. Szeptycka, M. Szarska, M. Terrani7, M. Terrani2, G. C. Trinchero, Raffaele Velotta, Sandro Ventura1, C. Vignoli4, Hui Wang9, Xuan Wang, J. Woo9, G. Xu8, Z. Xu8, X. Yang9, A. Zalewska, J. Zalipska, Chao Zhang8, Q. Zhang8, S. Zhen8, W. Zipper3 
TL;DR: The ICARUS T600 liquid argon (LAr) time projection chamber (TPC) is the largest LAr TPC ever built, with a size of about 500 tons of fully imaging mass as mentioned in this paper.
Abstract: We have constructed and operated the ICARUS T600 liquid argon (LAr) time projection chamber (TPC). The ICARUS T600 detector is the largest LAr TPC ever built, with a size of about 500 tons of fully imaging mass. The design and assembly of the detector relied on industrial support and represents the applications of concepts matured in laboratory tests to the kton scale. The ICARUS T600 was commissioned for a technical run that lasted about 3 months. During this period all the detector features were extensively tested with an exposure to cosmic-rays at surface with a resulting data collection of about 30 000 events. The detector was developed as the first element of a modular design. Thanks to the concept of modularity, it will be possible to realize a detector with several ktons active mass, to act as an observatory for astroparticle and neutrino physics at the Gran Sasso Underground Laboratory and a second-generation nucleon decay experiment. In this paper a description of the ICARUS T600 is given, detailing its design specifications, assembly procedures and acceptance tests. Commissioning procedures and results of the technical run are also reported, as well as results from the off-line event reconstruction.

478 citations


Journal ArticleDOI
TL;DR: The paper provides a comprehensive review made on more than 80 articles, with the main purpose of ascertaining which general objectives simulation is generally called to solve, which paradigms and simulation tools are more suitable, and deriving useful prescriptions on its applicability in decision-making processes within the supply chain context.

448 citations


Journal ArticleDOI
25 Jun 2004-Science
TL;DR: Time-series analysis shows that displacement occurs mainly during the high-precipitation season; during the 1997–1998 El Niño event, rates of range change increased to as much as 11 millimeters per year.
Abstract: High-resolution interferometric synthetic aperture radar (InSAR) permanent scatterer data allow us to resolve the rates and variations in the rates of slow-moving landslides. Satellite-to-ground distances (range changes) on landslides increase at rates of 5 to 7 millimeters per year, indicating average downslope sliding velocities from 27 to 38 millimeters per year. Time-series analysis shows that displacement occurs mainly during the high-precipitation season; during the 1997-1998 El Nino event, rates of range change increased to as much as 11 millimeters per year. The observed nonlinear relationship of creep and precipitation rates suggests that increased pore fluid pressures within the shallow subsurface may initiate and accelerate these features. Changes in the slope of a hill resulting from increases in the pore pressure and lithostatic stress gradients may then lead to landslides.

443 citations


Journal ArticleDOI
TL;DR: A detailed investigation of the reliability aspects in nonvolatile phase-change memories (PCM) is presented, covering the basic aspects related to high density array NVM, i.e., data retention, endurance, program and read disturbs.
Abstract: A detailed investigation of the reliability aspects in nonvolatile phase-change memories (PCM) is presented, covering the basic aspects related to high density array NVM, i.e., data retention, endurance, program and read disturbs. The data retention capabilities and the endurance characteristics of single PCM cells are analyzed, showing that data can be stored for 10 years at 110/spl deg/C and that a resistance difference of two order of magnitude between the cell states can be maintained for more than 10/sup 11/ programming cycles. The main mechanisms responsible for instabilities just before failure as well as for final device breakdown are also discussed. Finally, the impact of read and program disturbs are clearly assessed, showing with experimental data and simulated results that the crystallization induced during the cell read out and the thermal cross-talk due to adjacent bits programming do not affect the retention capabilities of the PCM cells.

409 citations


Journal ArticleDOI
TL;DR: In this paper, a detailed investigation of the time evolution for the low-field resistance R/sub off/ and the threshold voltage V/sub th/ in chalcogenide-based phase-change memory devices is presented.
Abstract: A detailed investigation of the time evolution for the low-field resistance R/sub off/ and the threshold voltage V/sub th/ in chalcogenide-based phase-change memory devices is presented. It is observed that both R/sub off/ and V/sub th/ increase and become stable with time and temperature, thus improving the cell readout window. Relying on a microscopic model, the drift of R/sub off/ and V/sub th/ is linked to the dynamic of the intrinsic traps typical of amorphous chalcogenides, thus providing for the first time a unified framework for the comprehension of chalcogenide materials transient behavior.

370 citations


Journal ArticleDOI
TL;DR: In this paper, a finite volume model of a solid oxide fuel cell is developed, which applies a detailed electrochemical and thermal analysis to a tubular SOFC of given geometry, material properties and assigned input flows.

368 citations


Journal ArticleDOI
TL;DR: The paper presents the mechanisms that compose the new MAC: the basic RR-ALOHA protocol, an efficient broadcast service and the reservation of point-to-point channels that exploit parallel transmissions.
Abstract: Ad-hoc networking, though an attractive solution for many applications, still has many unsolved issues, such as the hiddenterminal problem, flexible and prompt access, QoS provisioning, and efficient broadcast service. In this paper we present a MAC architecture able to solve the above issues in environments with no power consumption limitations, such as networks for inter-vehicle communications. This new architecture is based on a completely distributed access technique, RR-ALOHA, capable of dynamically establishing, for each active terminal in the network, a reliable single-hop broadcast channel on a slotted/framed structure. Though the proposed architecture uses a slotted channel it can be adapted to operate on the physical layer of different standards, including the UMTS Terrestrial Radio Access TDD, and IEEE 802.11. The paper presents the mechanisms that compose the new MAC: the basic RR-ALOHA protocol, an efficient broadcast service and the reservation of point-to-point channels that exploit parallel transmissions. Some basic performance figures are discussed to prove the effectiveness of the protocol.

Journal ArticleDOI
TL;DR: In this article, the evolution of solid-state avalanche detectors of single optical photons is discussed and issues for further progress are discussed, and the main technological issues that hamper the development of detectors with wide sensitive area and of array detectors with high filling factor are illustrated.
Abstract: The evolution of solid-state avalanche detectors of single optical photons is outlined and the issues for further progress are discussed. Physical phenomena that underlay the operation of the single-photon avalanche diodes (SPAD) and determine the performance are considered and their role is assessed (detection efficiency; dark-counting rate; afterpulsing; photon timing resolution; etc.). The main technological issues that hamper the development of detectors with wide sensitive area and of array detectors with high filling factor are illustrated. Silicon SPADs are the main focus of attention; infrared-sensitive SPADs in germanium and in compound semiconductors are also dealt with. The role of the active-quenching circuits (AQC) is assessed and the evolution is outlined up to integrated AQCs, which offer the prospect of monolithic integration of complete photon counter instruments.

Posted Content
TL;DR: In this paper, the authors provide empirical tests of the hypothesis of optimal cognitive distance, proposed by Nooteboom (1999), in two distinct empirical settings: pharmaceutical companies and biotech companies, as well as on interfirm agreements in ICT industries.
Abstract: This article provides empirical tests of the hypothesis of ‘optimal cognitive distance’, proposed by Nooteboom (1999, 2000), in two distinct empirical settings. Variety of cognition, needed for learning, has two dimensions: the number of agents with different cognition, and differences in cognition between them (cognitive distance). The hypothesis is that in interfirm relationships optimal learning entails a trade-off between the advantage of increased cognitive distance for a higher novelty value of a partner’s knowledge, and the disadvantage of less mutual understanding. If the value of learning is the mathematical product of novelty value and understandability, it has an inverse-U shaped relation with cognitive distance, with an optimum level that yields maximal value of learning. With auxiliary hypotheses, the hypothesis is tested on interfirm agreements between pharmaceutical companies and biotech companies, as well as on interfirm agreements in ICT industries.

Proceedings ArticleDOI
14 Mar 2004
TL;DR: A two-tier architecture is introduced: the first tier is an unsupervised clustering algorithm which reduces the network packets payload to a tractable size and the second tier is a traditional anomaly detection algorithm, whose efficiency is improved by the availability of data on the packet payload content.
Abstract: With the continuous evolution of the types of attacks against computer networks, traditional intrusion detection systems, based on pattern matching and static signatures, are increasingly limited by their need of an up-to-date and comprehensive knowledge base. Data mining techniques have been successfully applied in host-based intrusion detection. Applying data mining techniques on raw network data, however, is made difficult by the sheer size of the input; this is usually avoided by discarding the network packet contents.In this paper, we introduce a two-tier architecture to overcome this problem: the first tier is an unsupervised clustering algorithm which reduces the network packets payload to a tractable size. The second tier is a traditional anomaly detection algorithm, whose efficiency is improved by the availability of data on the packet payload content.

Journal ArticleDOI
TL;DR: In this article, a detailed analysis of the dependence of drag reduction on the oscillatory parameters allows us to address conflicting results hitherto reported in the literature, and we assess the possibility for the power saved to be higher than the power spent for the movement of the walls (when mechanical losses are neglected).
Abstract: Direct numerical simulations of the incompressible Navier–Stokes equations are employed to study the turbulent wall-shear stress in a turbulent channel flow forced by lateral sinusoidal oscillations of the walls. The objective is to produce a documented database of numerically computed friction reductions. To this aim, the particular numerical requirements for such simulations, owing for example to the time-varying direction of the skin-friction vector, are considered and appropriately accounted for. A detailed analysis of the dependence of drag reduction on the oscillatory parameters allows us to address conflicting results hitherto reported in the literature. At the Reynolds number of the present simulations, we compute a maximum drag reduction of 44.7%, and we assess the possibility for the power saved to be higher than the power spent for the movement of the walls (when mechanical losses are neglected). A maximum net energy saving of 7.3% is computed. Furthermore, the scaling of the amount of drag reduction is addressed. A parameter, which depends on both the maximum wall velocity and the period of the oscillation, is found to be linearly related to drag reduction, as long as the half-period of the oscillation is shorter than a typical lifetime of the turbulent near-wall structures. For longer periods of oscillation, the scaling parameter predicts that drag reduction will decrease to zero more slowly than the numerical data. The same parameter also describes well the optimum period of oscillation for fixed maximum wall displacement, which is smaller than the optimum period for fixed maximum wall velocity, and depends on the maximum displacement itself.

Journal ArticleDOI
TL;DR: In this paper, the effect of replacing part of portland cement with fly ash and bottom ash, both from municipal solid waste incinerators (MSWIs), was investigated. And the results showed that MSWI bottom ash is potentially attractive as mineral addition for the production of concrete, provided that the risk of entrapment of hydrogen bubbles produced by corrosion of aluminium metallic particles in the fresh concrete is prevented.

Journal ArticleDOI
TL;DR: The threshold switching mechanism in amorphous chalcogenides has been investigated in this article, showing experimental data that once and for all demonstrate its electronic nature and the physical mechanisms responsible for the switching to the highly conductive state are discussed and the impact of cumulative read-out pulses is also investigated, showing that phase-change transitions induced by usual reading operations in phase change memory cells are completely negligible.
Abstract: The threshold switching mechanism in amorphous chalcogenides is investigated, showing experimental data that once and for all demonstrate its electronic nature. The physical mechanisms responsible for the switching to the highly conductive state are discussed and the impact of cumulative read-out pulses is also investigated, showing that phase-change transitions induced by usual reading operations in phase-change memory cells are completely negligible.

Journal ArticleDOI
TL;DR: The International Reactor Innovative and Secure (IRIS) as discussed by the authors is an integral, modular, medium size (335 MWe) PWR, which has been under development since the turn of the century by an international consortium led by Westinghouse and including over 20 organizations from nine countries.

Journal ArticleDOI
TL;DR: Within-breath respiratory system reactance provides an accurate, reliable and noninvasive technique to detect expiratory flow limitation in patients with chronic obstructive pulmonary disease.
Abstract: Expiratory flow limitation (EFL) during tidal breathing is a major determinant of dynamic hyperinflation and exercise limitation in chronic obstructive pulmonary disease (COPD). Current methods of detecting this are either invasive or unsuited to following changes breath-by-breath. It was hypothesised that tidal flow limitation would substantially reduce the total respiratory system reactance (Xrs) during expiration, and that this reduction could be used to reliably detect if EFL was present. To test this, 5-Hz forced oscillations were applied at the mouth in seven healthy subjects and 15 COPD patients (mean +/- sD forced expiratory volume in one second was 36.8 +/- 11.5% predicted) during quiet breathing. COPD breaths were analysed (n=206) and classified as flow-limited if flow decreased as alveolar pressure increased, indeterminate if flow decreased at constant alveolar pressure, or nonflow-limited. Of these, 85 breaths were flow-limited, 80 were not and 41 were indeterminate. Among other indices, mean inspiratory minus mean expiratory Xrs (deltaXrs) and minimum expiratory Xrs (Xexp,min) identified flow-limited breaths with 100% specificity and sensitivity using a threshold between 2.53-3.12 cmH2O x s x L(-1) (deltaXrs) and -7.38- -6.76 cmH2O x s x L(-1) (Xexp,min) representing 6.0% and 3.9% of the total range of values respectively. No flow-limited breaths were seen in the normal subjects by either method. Within-breath respiratory system reactance provides an accurate, reliable and noninvasive technique to detect expiratory flow limitation in patients with chronic obstructive pulmonary disease.

Journal ArticleDOI
TL;DR: In this paper, the transient response method (TRM) and FT-IR spectroscopy were used to investigate the adaption of NO, NO/O 2, and NO 2 on a Pt-Ba-Al-O system.

Journal ArticleDOI
TL;DR: In this paper, the authors investigated the determinants of the start-up size of new technology-based firms, focusing on the characteristics of founders, notably their human capital, and found that the specific component of human capital associated with industry-specific professional knowledge and managerial and entrepreneurial experiences had a greater positive impact on the initial firm size than the generic component, proxied by education and general (i.e., non-industry-specific) working experience.

Book ChapterDOI
TL;DR: This chapter addresses the problem of developing models for the numerical simulation of the human circulatory system, and particularly focuses on the issue of hemodynamics in large human arteries.
Abstract: Publisher Summary The development of mathematical models, algorithms and numerical simulation tools for the investigation of the human cardiovascular system has received a great impulse in the past years This chapter addresses the problem of developing models for the numerical simulation of the human circulatory system It particularly focuses on the problem of hemodynamics in large human arteries There are several important aspects, which require the use of sophisticated mathematical and numerical tools, such as the reconstruction of geometries from medical data; the transport of biochemicals in blood and vessel wall tissue; the heart dynamics; and blood rheology Besides, the need of validating the models calls for development of accurate in-vivo measurement techniques The number and complexity of the mathematical, numerical and technological problems involved makes the development of tools for accurate, reliable and efficient simulations of the human cardiovascular system one of the challenges of the next decades

Proceedings ArticleDOI
13 Dec 2004
TL;DR: In this paper, the chalcogenide phase-change mechanism and phase distribution in the programmed cell is studied by both experiments and a numerical model, which self-consistently addresses the electrical-thermal conduction phase transition.
Abstract: We analyzed the programming dynamics in phase-change memory (PCM) cells. The chalcogenide phase-change mechanism and phase distribution in the programmed cell is studied by both experiments and a numerical model, which self-consistently addresses the electrical-thermal conduction phase transition. We show that the reset-set transition is strongly coupled to the electronic switching in the amorphous phase, thus supporting the need for a self-consistent electrothermal-phase transition model to correctly account for all experimental evidences.

Journal ArticleDOI
TL;DR: Theoretical computations and specific Raman experiments demonstrate that a molecular approach provides a unified key to the interpretation of the Raman response both of linear polyconjugated polymers (polyacetylene) and of nanostructured graphitic materials.
Abstract: The effect of the confinement of electrons in one and twodimensional domains is illustrated with several examples ranging from linear polyene chains to planar molecules with honeycomb structure. Th...

Journal ArticleDOI
TL;DR: The presented techniques are based on the observation that the wireless radio channel can be parametrized as a combination of paths, each characterized by a delay and a complex amplitude, which shows fast temporal variations due to the mobility of terminals while the delays are almost constant over a large number of OFDM symbols.
Abstract: In orthogonal frequency division multiplexing (OFDM) systems over fast-varying fading channels, channel estimation and tracking is generally carried out by transmitting known pilot symbols in given positions of the frequency-time grid. The traditional approach consists of two steps. First, the least-squares (LS) estimate is obtained over the pilot subcarriers. Then, this preliminary estimate is interpolated/smoothed over the entire frequency-time grid. In this paper, we propose to add an intermediate step, whose purpose is to increase the accuracy of the estimate over the pilot subcarriers. The presented techniques are based on the observation that the wireless radio channel can be parametrized as a combination of paths, each characterized by a delay and a complex amplitude. The amplitudes show fast temporal variations due to the mobility of terminals while the delays (and their associated delay-subspace) are almost constant over a large number of OFDM symbols. We propose to track the delay-subspace by a subspace tracking algorithm and the amplitudes by the least mean square algorithm (or modifications of the latter). The approach can be extended to multiple input multiple output OFDM or multicarrier code-division multiple-access systems. Analytical results and simulations prove the relevant benefits of the novel structure.

Journal ArticleDOI
TL;DR: In this article, the authors proposed a frequency divider that combines the conventional and the extended true-single-phase-clock logics for multigigahertz phase-locked loops.
Abstract: The adoption of dynamic dividers in CMOS phase-locked loops for multigigahertz applications allows to reduce the power consumption substantially without impairing the phase noise and the power supply sensitivity of the phase-locked loop (PLL). A 5-GHz frequency synthesizer integrated in a 0.25-/spl mu/m CMOS technology demonstrates a total power consumption of 13.5 mW. The frequency divider combines the conventional and the extended true-single-phase-clock logics. The oscillator employs a rail-to-rail topology in order to ensure a proper divider function. This PLL intended for wireless LAN applications can synthesize frequencies between 5.14 and 5.70 GHz in steps of 20 MHz. The reference spurs at 10-MHz offset are as low as -70 dBc and the phase noise is lower than -116 dBc/Hz at 1 MHz over the whole tuning range.

Journal ArticleDOI
01 Mar 2004-Thorax
TL;DR: Accurate measurement of chest wall volume can identify the different patterns of respiratory muscle activation during exercise, and dynamic hyperinflation is not the only mechanism limiting exercise performance in patients with stable COPD.
Abstract: Background: Dynamic hyperinflation of the lungs impairs exercise performance in chronic obstructive pulmonary disease (COPD). However, it is unclear which patients are affected by dynamic hyperinflation and how the respiratory muscles respond to the change in lung volume. Methods: Using optoelectronic plethysmography, total and regional chest wall volumes were measured non-invasively in 20 stable patients with COPD (mean (SD) forced expiratory volume in 1 second 43.6 (11.6)% predicted) and dynamic hyperinflation was tracked breath by breath to test if this was the mechanism of exercise limitation. Resting ventilation, breathing pattern, symptoms, rib cage and abdominal volumes were recorded at rest and during symptom limited cycle ergometry. Pleural, abdominal, and transdiaphragmatic pressures were measured in eight patients. Results: End expiratory chest wall volume increased by a mean (SE) of 592 (80) ml in 12 patients (hyperinflators) but decreased by 462 (103) ml in eight (euvolumics). During exercise, tidal volume increased in euvolumic patients by reducing end expiratory abdominal volume while in hyperinflators tidal volume increased by increasing end inspiratory abdominal and rib cage volumes. The maximal abdominal pressure was 22.1 (9.0) cm H 2 O in euvolumic patients and 7.6 (2.6) cm H 2 O in hyperinflators. Euvolumic patients were as breathless as hyperinflators but exercised for less time and reached lower maximum workloads (p Conclusions: Dynamic hyperinflation is not the only mechanism limiting exercise performance in patients with stable COPD. Accurate measurement of chest wall volume can identify the different patterns of respiratory muscle activation during exercise.

Journal ArticleDOI
TL;DR: In this paper, the Lagrangian action functional on suitable classes of symmetric loops yields collisionless periodic orbits of the n-body problem, provided that some simple conditions on the symmetry group are satisfied.
Abstract: We show that the minimization of the Lagrangian action functional on suitable classes of symmetric loops yields collisionless periodic orbits of the n-body problem, provided that some simple conditions on the symmetry group are satisfied. More precisely, we give a fairly general condition on symmetry groups G of the loop space Λ for the n-body problem (with potential of homogeneous degree -α, with α>0) which ensures that the restriction of the Lagrangian action $\mathcal{A}$ to the space Λ G of G-equivariant loops is coercive and its minimizers are collisionless, without any strong force assumption. In proving that local minima of Λ G are free of collisions we develop an averaging technique based on Marchal’s idea of replacing some of the point masses with suitable shapes (see [10]). As an application, several new orbits can be found with some appropriate choice of G. Furthermore, the result can be used to give a simplified and unitary proof of the existence of many already known minimizing periodic orbits.

Journal ArticleDOI
TL;DR: The model suggests that the ability to control complexity within manufacturing and logistic systems can be regarded as a core competence in order to jointly improve efficiency and effectiveness at a supply chain wide scale.

Journal ArticleDOI
TL;DR: In this article, the impact of water drops on thin liquid films was studied by still photography, and quantitative results were obtained by a proper image analysis technique, and the time evolution of various parameters like the crown diameter, the crown height and the secondary drop diameters were reported.
Abstract: This paper reports on an experimental study of the impact of water drops on thin liquid films. The morphology of the impact was studied by still photography, and quantitative results were obtained by a proper image analysis technique. The time evolution of various parameters like the crown diameter, the crown height, and the secondary drop diameters are reported, and these experimental parameters are correlated and compared to available theoretical models. A particular set-up of the acquisition system allowed us to photograph the splash from below the solid wall, allowing the first estimation of the crown thickness and the total number of jets protruding from the crown rim as a function of time. The results indicate that, for the range of the parameters investigated, there is not a strong dependence on the film thickness. The evolution of the crown height depends on the impact Weber number, whereas its growing velocity and the crown thickness evolution are almost independent of Weber number.