scispace - formally typeset
Search or ask a question
Institution

Polytechnic University of Milan

EducationMilan, Italy
About: Polytechnic University of Milan is a education organization based out in Milan, Italy. It is known for research contribution in the topics: Finite element method & Population. The organization has 18231 authors who have published 58416 publications receiving 1229711 citations. The organization is also known as: PoliMi & L-NESS.


Papers
More filters
Journal ArticleDOI
TL;DR: A phenomenological model for platelet cumulative damage, identified by means of genetic algorithms (GAs) was correlated with in vitro experiments conducted in a Hemodynamic Shearing Device (HSD), and model predictions were in very good agreement with the experimental results.
Abstract: The need to optimize the thrombogenic performance of blood recirculating cardiovascular devices, e.g., prosthetic heart valves (PHV) and ventricular assist devices (VAD), is accentuated by the fact that most of them require lifelong anticoagulation therapy that does not eliminate the risk of thromboembolic complications. The formation of thromboemboli in the flow field of these devices is potentiated by contact with foreign surfaces and regional flow phenomena that stimulate blood clotting, especially platelets. With the lack of appropriate methodology, device manufacturers do not specifically optimize for thrombogenic performance. Such optimization can be facilitated by formulating a robust numerical methodology with predictive capabilities of flow-induced platelet activation. In this study, a phenomenological model for platelet cumulative damage, identified by means of genetic algorithms (GAs), was correlated with in vitro experiments conducted in a Hemodynamic Shearing Device (HSD). Platelets were uniformly exposed to flow shear representing the lower end of the stress levels encountered in devices, and platelet activity state (PAS) was measured in response to six dynamic shear stress waveforms representing repeated passages through a device, and correlated to the predictions of the damage accumulation model. Experimental results demonstrated an increase in PAS with a decrease in "relaxation" time between pulses. The model predictions were in very good agreement with the experimental results.

199 citations

Journal ArticleDOI
TL;DR: Through the analysis of three case studies of firms that digitally transformed their business—namely ABB, CNH Industrial, and Vodafone—this article presents a framework than can help companies implement their digital transformation strategy and thereby renovate their business model.
Abstract: The rapid growth of digital technologies and the extraordinary amount of data that devices and applications collect each day are increasingly driving companies to radically transform the business a

199 citations

Journal ArticleDOI
TL;DR: In this article, an event-triggered robust fuzzy adaptive prescribed performance finite-time control strategy is presented for a class of strict-feedback nonlinear systems with external disturbances, and the dynamic surface control technique is applied to address the computational complexity problem.
Abstract: In this article, an event-triggered robust fuzzy adaptive prescribed performance finite-time control strategy is presented for a class of strict-feedback nonlinear systems with external disturbances. The relative-threshold-based event-triggered signal is introduced to reduce communication burden, and the dynamic surface control technique is applied to address the computational complexity problem. A disturbance observer is designed to estimate the compounded disturbances, which are composed of external disturbances and fuzzy approximation errors. The proposed control strategy can guarantee that the closed-loop system is semiglobally practically finite-time stable, and the tracking error converges to a small residual set by incorporating the prescribed performance bound in finite-time. Finally, simulation results are provided to verify the effectiveness of the proposed robust fuzzy control strategy.

198 citations

Journal ArticleDOI
TL;DR: A new notion of stability (Exponential Mean stability) is introduced and is shown to be equivalent to the standard notion of 1-moment stability, and various sufficient conditions for Exponential Almost-Sure stability are worked out, with different levels of conservatism.

198 citations

Journal ArticleDOI
TL;DR: In this article, the authors analyzed the self-healing properties of early-age concretes, engineered using a crystalline admixture (4% by the weight of cement), by measuring the permeability of cracked specimens and their crack width.

198 citations


Authors

Showing all 18743 results

NameH-indexPapersCitations
Alex J. Barker132127384746
Pierluigi Zotto128119778259
Andrea C. Ferrari126636124533
Marco Dorigo10565791418
Marcello Giroletti10355841565
Luciano Gattinoni10361048055
Luca Benini101145347862
Alberto Sangiovanni-Vincentelli9993445201
Surendra P. Shah9971032832
X. Sunney Xie9822544104
Peter Nijkamp97240750826
Nicola Neri92112241986
Ursula Keller9293433229
A. Rizzi9165340038
Martin J. Blunt8948529225
Network Information
Related Institutions (5)
Delft University of Technology
94.4K papers, 2.7M citations

96% related

Georgia Institute of Technology
119K papers, 4.6M citations

94% related

École Polytechnique Fédérale de Lausanne
98.2K papers, 4.3M citations

94% related

ETH Zurich
122.4K papers, 5.1M citations

93% related

Karlsruhe Institute of Technology
82.1K papers, 2.1M citations

92% related

Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023302
2022811
20214,151
20204,301
20193,831
20183,767