Institution
Polytechnic University of Valencia
Education•Valencia, Spain•
About: Polytechnic University of Valencia is a education organization based out in Valencia, Spain. It is known for research contribution in the topics: Catalysis & Population. The organization has 16282 authors who have published 40162 publications receiving 850234 citations.
Topics: Catalysis, Population, Combustion, Diesel fuel, Membrane
Papers published on a yearly basis
Papers
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TL;DR: Polymer optical fiber Bragg gratings (POFBGs) as discussed by the authors have been used in a wide range of applications, such as sensors, sensors, and actuators, with the consequences of fiber breakage in situ being less hazardous than silica.
Abstract: Interest in polymer optical fiber Bragg gratings (POFBGs) arises from the different material properties and sensing modalities brought by polymers relative to silica. Polymer fibers typically offer twice the sensitivity to temperature of conventional silica fiber and increased sensitivity to strain overall. In addition, polymer fibers have higher elastic limits and as a result a larger range of operation for physical constraints. While some polymers are effectively humidity insensitive, others present inherent humidity sensitivity. Their organic properties also allow a variety of chemical processes to create (bio)chemical sensors, with the consequences of fiber breakage in situ being less hazardous than silica. These attributes have led to the use of POFBGs for applications that remain complex using silica fibers. This review paper covers the progress toward commercialization and the increasing number of specific applications.
180 citations
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TL;DR: It is shown that “survival of the flattest” can also occur in biological entities by analyzing the outcome of competition between two viroid species coinfecting the same plant.
Abstract: The “survival of the fittest” is the paradigm of Darwinian evolution in which the best-adapted replicators are favored by natural selection. However, at high mutation rates, the fittest organisms are not necessarily the fastest replicators but rather are those that show the greatest robustness against deleterious mutational effects, even at the cost of a low replication rate. This scenario, dubbed the “survival of the flattest”, has so far only been shown to operate in digital organisms. We show that “survival of the flattest” can also occur in biological entities by analyzing the outcome of competition between two viroid species coinfecting the same plant. Under optimal growth conditions, a viroid species characterized by fast population growth and genetic homogeneity outcompeted a viroid species with slow population growth and a high degree of variation. In contrast, the slow-growth species was able to outcompete the fast species when the mutation rate was increased. These experimental results were supported by an in silico model of competing viroid quasispecies.
180 citations
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TL;DR: This work takes advantage of the high lysosomal β‐galactosidase activity of senescent cells to design a drug delivery system based on the encapsulation of drugs with galacto‐oligosaccharides, and shows that gal‐encapsulation reduces the toxic side effects of the cytotoxic drugs.
Abstract: Senescent cells accumulate in multiple aging-associated diseases, and eliminating these cells has recently emerged as a promising therapeutic approach. Here, we take advantage of the high lysosomal β-galactosidase activity of senescent cells to design a drug delivery system based on the encapsulation of drugs with galacto-oligosaccharides. We show that gal-encapsulated fluorophores are preferentially released within senescent cells in mice. In a model of chemotherapy-induced senescence, gal-encapsulated cytotoxic drugs target senescent tumor cells and improve tumor xenograft regression in combination with palbociclib. Moreover, in a model of pulmonary fibrosis in mice, gal-encapsulated cytotoxics target senescent cells, reducing collagen deposition and restoring pulmonary function. Finally, gal-encapsulation reduces the toxic side effects of the cytotoxic drugs. Drug delivery into senescent cells opens new diagnostic and therapeutic applications for senescence-associated disorders.
180 citations
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TL;DR: In this article, a revision of 45 recent advances in the area of optical systems for freshness monitoring is reported and a discussion about the main research challenges and opportunities that will be faced by intelligent packaging in the coming years is included.
179 citations
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TL;DR: In this paper, the authors reviewed the recent advances in this emerging field which is dubbed as integrated microwave photonics and the prospective of the field is discussed, and the key integrated MWP technologies are reviewed.
Abstract: Microwave photonics (MWP) is an emerging field in which radio frequency (RF) signals are generated, distributed, processed and analyzed using the strength of photonic techniques. It is a technology that enables various functionalities which are not feasible to achieve only in the microwave domain. A particular aspect that recently gains significant interests is the use of photonic integrated circuit (PIC) technology in the MWP field for enhanced functionalities and robustness as well as the reduction of size, weight, cost and power consumption. This article reviews the recent advances in this emerging field which is dubbed as integrated microwave photonics. Key integrated MWP technologies are reviewed and the prospective of the field is discussed.
179 citations
Authors
Showing all 16503 results
Name | H-index | Papers | Citations |
---|---|---|---|
Avelino Corma | 134 | 1049 | 89095 |
Bruce D. Hammock | 111 | 1409 | 57401 |
Geoffrey A. Ozin | 108 | 811 | 47504 |
Wolfgang J. Parak | 102 | 469 | 43307 |
Hermenegildo García | 97 | 792 | 46585 |
María Vallet-Regí | 95 | 711 | 41641 |
Albert Ferrando | 87 | 419 | 36793 |
Rajendra Prasad | 86 | 945 | 29526 |
J.J. Garcia-Luna-Aceves | 86 | 602 | 25151 |
George W. Huber | 84 | 280 | 37964 |
Juan J. Calvete | 81 | 458 | 22646 |
Juan M. Feliu | 80 | 544 | 23147 |
Amparo Chiralt | 78 | 298 | 18378 |
Michael Tsapatsis | 77 | 375 | 20051 |
Josep Redon | 77 | 488 | 81395 |