Institution
Pompeu Fabra University
Education•Barcelona, Spain•
About: Pompeu Fabra University is a education organization based out in Barcelona, Spain. It is known for research contribution in the topics: Population & Gene. The organization has 8093 authors who have published 23570 publications receiving 858431 citations. The organization is also known as: Universitat Pompeu Fabra & UPF.
Topics: Population, Gene, European union, Genome, Context (language use)
Papers published on a yearly basis
Papers
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Babraham Institute1, Pompeu Fabra University2, Science for Life Laboratory3, Institute of Molecular Pathology and Immunology of the University of Porto4, Zoological Society of London5, University of Stuttgart6, University of Cambridge7, Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto8, University of Bristol9, University of Sussex10, Wellcome Trust Sanger Institute11
TL;DR: In this paper, the authors sequenced genomes, microRNAs, and multiple transcriptomes and methylomes from individual brains in a wasp (Polistes canadensis) and an ant (Dinoponera quadriceps) that live in simple eusocial societies.
Abstract: Phenotypic plasticity is important in adaptation and shapes the evolution of organisms. However, we understand little about what aspects of the genome are important in facilitating plasticity. Eusocial insect societies produce plastic phenotypes from the same genome, as reproductives (queens) and nonreproductives (workers). The greatest plasticity is found in the simple eusocial insect societies in which individuals retain the ability to switch between reproductive and nonreproductive phenotypes as adults. We lack comprehensive data on the molecular basis of plastic phenotypes. Here, we sequenced genomes, microRNAs (miRNAs), and multiple transcriptomes and methylomes from individual brains in a wasp (Polistes canadensis) and an ant (Dinoponera quadriceps) that live in simple eusocial societies. In both species, we found few differences between phenotypes at the transcriptional level, with little functional specialization, and no evidence that phenotype-specific gene expression is driven by DNA methylation or miRNAs. Instead, phenotypic differentiation was defined more subtly by nonrandom transcriptional network organization, with roles in these networks for both conserved and taxon-restricted genes. The general lack of highly methylated regions or methylome patterning in both species may be an important mechanism for achieving plasticity among phenotypes during adulthood. These findings define previously unidentified hypotheses on the genomic processes that facilitate plasticity and suggest that the molecular hallmarks of social behavior are likely to differ with the level of social complexity.
182 citations
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TL;DR: It is shown that success in academia is predictable, and both the scientist's gender and the rank of their university are also of importance, suggesting that non-publication features play a statistically significant role in the academic hiring process.
182 citations
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University of the Philippines Manila1, King Abdulaziz Medical City2, University of Sydney3, Maastricht University Medical Centre4, Synlab Group5, University of Lausanne6, University of South Carolina7, Emory University8, China Medical University (Taiwan)9, National Taiwan University10, University of Washington11, Konyang University12, University of Havana13, National University of Malaysia14, Copenhagen University Hospital15, University of Bergen16, National Health Laboratory Service17, Universidad del Desarrollo18, University of Cambridge19, Babeș-Bolyai University20, University of Arkansas for Medical Sciences21, Stanford University22, University of Porto23, Cone Health24, University of Saint Mary25, University of British Columbia26, Pompeu Fabra University27, Hebrew University of Jerusalem28, University of Cape Town29, University Malaya Medical Centre30, Northwestern University31
TL;DR: The global state of genetic counseling as a profession is described as fully as possible, estimating that in 2018 there are nearly 7000 genetic counselors with the profession established or developing in no less than 28 countries.
Abstract: The profession of genetic counseling (also called genetic counselling in many countries) began nearly 50 years ago in the United States, and has grown internationally in the past 30 years. While there have been many papers describing the profession of genetic counseling in individual countries or regions, data remains incomplete and has been published in diverse journals with limited access. As a result of the 2016 Transnational Alliance of Genetic Counseling (TAGC) conference in Barcelona, Spain, and the 2017 World Congress of Genetic Counselling in the UK, we endeavor to describe as fully as possible the global state of genetic counseling as a profession. We estimate that in 2018 there are nearly 7000 genetic counselors with the profession established or developing in no less than 28 countries.
182 citations
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08 Sep 2014TL;DR: A survey of the field of Music Information Retrieval, in particular paying attention to latest developments, such as semantic auto-tagging and user-centric retrieval and recommendation approaches, is provided.
Abstract: We provide a survey of the field of Music Information Retrieval (MIR), in particular paying attention to latest developments, such as semantic auto-tagging and user-centric retrieval and recommendation approaches. We first elaborate on well-established and proven methods for feature extraction and music indexing, from both the audio signal and contextual data sources about music items, such as web pages or collaborative tags. These in turn enable a wide variety of music retrieval tasks, such as semantic music search or music identification ("query by example"). Subsequently, we review current work on user analysis and modeling in the context of music recommendation and retrieval, addressing the recent trend towards user-centric and adaptive approaches and systems. A discussion follows about the important aspect of how various MIR approaches to different problems are evaluated and compared. Eventually, a discussion about the major open challenges concludes the survey.
182 citations
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TL;DR: Differences in MDMA metabolism among animal species might account for different sensitivities to its neurotoxic effects, as well as limit allometric scaling across animal models.
182 citations
Authors
Showing all 8248 results
Name | H-index | Papers | Citations |
---|---|---|---|
Andrei Shleifer | 171 | 514 | 271880 |
Paul Elliott | 153 | 773 | 103839 |
Bert Brunekreef | 124 | 806 | 81938 |
Philippe Aghion | 122 | 507 | 73438 |
Anjana Rao | 118 | 337 | 61395 |
Jordi Sunyer | 115 | 798 | 57211 |
Kenneth J. Arrow | 113 | 411 | 111221 |
Xavier Estivill | 110 | 673 | 59568 |
Roderic Guigó | 108 | 304 | 106914 |
Mark J. Nieuwenhuijsen | 107 | 647 | 49080 |
Jordi Alonso | 107 | 523 | 64058 |
Alfonso Valencia | 106 | 542 | 55192 |
Luis Serrano | 105 | 452 | 42515 |
Vadim N. Gladyshev | 102 | 490 | 34148 |
Josep M. Antó | 100 | 493 | 38663 |