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Institution

Pompeu Fabra University

EducationBarcelona, Spain
About: Pompeu Fabra University is a education organization based out in Barcelona, Spain. It is known for research contribution in the topics: Population & Gene. The organization has 8093 authors who have published 23570 publications receiving 858431 citations. The organization is also known as: Universitat Pompeu Fabra & UPF.


Papers
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Journal ArticleDOI
TL;DR: It is suggested that stem cells of embryonic, neural, and hematopoietic origin are heterogeneous, with cells moving between two or more metastable states.

311 citations

Journal ArticleDOI
01 Dec 2005-Surgery
TL;DR: Morbidity of bilateral CND is significant, and its systematic implementation in the absence on gross nodal involvement requires reassessment.

310 citations

Journal ArticleDOI
TL;DR: In this paper, the authors proposed an algorithm to increase the resolution of multispectral satellite images knowing the panchromatic image at high resolution and the spectral channels at lower resolution.
Abstract: We propose an algorithm to increase the resolution of multispectral satellite images knowing the panchromatic image at high resolution and the spectral channels at lower resolution. Our algorithm is based on the assumption that, to a large extent, the geometry of the spectral channels is contained in the topographic map of its panchromatic image. This assumption, together with the relation of the panchromatic image to the spectral channels, and the expression of the low-resolution pixel in terms of the high-resolution pixels given by some convolution kernel followed by subsampling, constitute the elements for constructing an energy functional (with several variants) whose minima will give the reconstructed spectral images at higher resolution. We discuss the validity of the above approach and describe our numerical procedure. Finally, some experiments on a set of multispectral satellite images are displayed.

309 citations

Journal ArticleDOI
TL;DR: Investigating wrinkled biofilms of Bacillus subtilis discovered a pattern of localized cell death that spatially focuses mechanical forces, and thereby initiates wrinkle formation, which was able to generate artificial wrinkle patterns within biofilmms.
Abstract: From microbial biofilm communities to multicellular organisms, 3D macroscopic structures develop through poorly understood interplay between cellular processes and mechanical forces. Investigating wrinkled biofilms of Bacillus subtilis, we discovered a pattern of localized cell death that spatially focuses mechanical forces, and thereby initiates wrinkle formation. Deletion of genes implicated in biofilm development, together with mathematical modeling, revealed that ECM production underlies the localization of cell death. Simultaneously with cell death, we quantitatively measured mechanical stiffness and movement in WT and mutant biofilms. Results suggest that localized cell death provides an outlet for lateral compressive forces, thereby promoting vertical mechanical buckling, which subsequently leads to wrinkle formation. Guided by these findings, we were able to generate artificial wrinkle patterns within biofilms. Formation of 3D structures facilitated by cell death may underlie self-organization in other developmental systems, and could enable engineering of macroscopic structures from cell populations.

309 citations


Authors

Showing all 8248 results

NameH-indexPapersCitations
Andrei Shleifer171514271880
Paul Elliott153773103839
Bert Brunekreef12480681938
Philippe Aghion12250773438
Anjana Rao11833761395
Jordi Sunyer11579857211
Kenneth J. Arrow113411111221
Xavier Estivill11067359568
Roderic Guigó108304106914
Mark J. Nieuwenhuijsen10764749080
Jordi Alonso10752364058
Alfonso Valencia10654255192
Luis Serrano10545242515
Vadim N. Gladyshev10249034148
Josep M. Antó10049338663
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202349
2022248
20211,903
20201,930
20191,763
20181,660