Institution
Pompeu Fabra University
Education•Barcelona, Spain•
About: Pompeu Fabra University is a education organization based out in Barcelona, Spain. It is known for research contribution in the topics: Population & Gene. The organization has 8093 authors who have published 23570 publications receiving 858431 citations. The organization is also known as: Universitat Pompeu Fabra & UPF.
Topics: Population, Gene, European union, Genome, Context (language use)
Papers published on a yearly basis
Papers
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TL;DR: The findings on immigrants from Spain highlight the transitory nature of the 'healthy immigrant effect', and that action on inequality in socio-economic determinants affecting migrant groups should not be deferred.
294 citations
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CINVESTAV1, University of Arizona2, Universidad de Guanajuato3, University at Buffalo4, Chongqing University of Science and Technology5, Universidad Veracruzana6, Michigan State University7, University of Guadalajara8, Nanyang Technological University9, Pennsylvania State University10, Pompeu Fabra University11, Max Planck Society12, Indiana University13, Rutgers University14, Donald Danforth Plant Science Center15
TL;DR: The compressed architecture of the U. gibba genome indicates that a small fraction of intergenic DNA, with few or no active retrotransposons, is sufficient to regulate and integrate all the processes required for the development and reproduction of a complex organism.
Abstract: It has been argued that the evolution of plant genome size is principally unidirectional and increasing owing to the varied action of wholegenome duplications (WGDs) and mobile element proliferation 1 . However, extreme genome size reductions have been reported in the angiosperm family tree. Here we report the sequence of the 82megabase genome of the carnivorous bladderwort plant Utricularia gibba. Despite its tiny size, the U. gibba genome accommodates a typical number of genes for a plant, with the main difference from other plant genomes arising from a drastic reduction in non-genic DNA. Unexpectedly, we identified at least three rounds of WGD in U. gibba since common ancestry with tomato (Solanum) and grape (Vitis). The compressed architecture of the U. gibba genome indicates that a small fraction of intergenic DNA, with few or no active retrotransposons, is sufficient to regulate and integrate all the processes required for the development and reproduction of a complex organism. Like other carnivorous plants, Utricularia (Lentibulariaceae) species derive nitrogen and phosphorus supplements by trapping and digesting prey organisms 2,3 . Lentibulariaceae are asterid angiosperms closely related to the model plants snapdragon (Antirrhinum) and monkey
294 citations
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Federal University of Rio de Janeiro1, Simon Fraser University2, National University of La Plata3, Oswaldo Cruz Foundation4, Washington University in St. Louis5, University of the Republic6, European Bioinformatics Institute7, National Institutes of Health8, Federal University of Uberlandia9, Universidade Federal de Minas Gerais10, Sao Paulo State University11, State University of Norte Fluminense12, Johns Hopkins University13, University of Notre Dame14, Universidade Federal Rural do Rio de Janeiro15, Pompeu Fabra University16, Centre national de la recherche scientifique17, University of Toronto18, Centers for Disease Control and Prevention19, Instituto Politécnico Nacional20, Florida International University21, Universidade Federal do Espírito Santo22, University of Illinois at Urbana–Champaign23, University of Santiago de Compostela24, Virginia Tech25, University of Cambridge26, University of Manitoba27
TL;DR: The first genome sequence of a nondipteran insect vector of an important human parasitic disease is described, which provides critical information on the physiology and evolution of this important vector species and should be instrumental for the development of innovative disease control methods.
Abstract: Rhodnius prolixus not only has served as a model organism for the study of insect physiology, but also is a major vector of Chagas disease, an illness that affects approximately seven million people worldwide. We sequenced the genome of R. prolixus, generated assembled sequences covering 95% of the genome (∼ 702 Mb), including 15,456 putative protein-coding genes, and completed comprehensive genomic analyses of this obligate blood-feeding insect. Although immune-deficiency (IMD)-mediated immune responses were observed, R. prolixus putatively lacks key components of the IMD pathway, suggesting a reorganization of the canonical immune signaling network. Although both Toll and IMD effectors controlled intestinal microbiota, neither affected Trypanosoma cruzi, the causal agent of Chagas disease, implying the existence of evasion or tolerance mechanisms. R. prolixus has experienced an extensive loss of selenoprotein genes, with its repertoire reduced to only two proteins, one of which is a selenocysteine-based glutathione peroxidase, the first found in insects. The genome contained actively transcribed, horizontally transferred genes from Wolbachia sp., which showed evidence of codon use evolution toward the insect use pattern. Comparative protein analyses revealed many lineage-specific expansions and putative gene absences in R. prolixus, including tandem expansions of genes related to chemoreception, feeding, and digestion that possibly contributed to the evolution of a blood-feeding lifestyle. The genome assembly and these associated analyses provide critical information on the physiology and evolution of this important vector species and should be instrumental for the development of innovative disease control methods.
293 citations
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TL;DR: In this paper, the effect of providing relative performance feedback information on performance under piece-rate incentives was studied in a real-effort setting, where students received information that allowed them to know whether they were above (below) the class average as well as the distance from this average.
Abstract: We study the effect of providing relative performance feedback information on performance under piece-rate incentives. A natural experiment that took place in a high school offers an unusual opportunity to test this effect in a real-effort setting. For one year only, students received information that allowed them to know whether they were above (below) the class average as well as the distance from this average. We exploit a rich panel data set and find that the provision of this information led to an increase of 5% in students’ grades. Moreover, the effect was significant for the whole distribution. However, once the information was removed the effect disappeared. To rule out the concern that the effect may be driven by teachers within the school, we verify our results using national level exams (externally graded) for the same students, and the effect remains.
293 citations
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TL;DR: Evidence that people using a foreign language make substantially more utilitarian decisions when faced with moral dilemmas is reported, arguing that this stems from the reduced emotional response elicited by the foreign language, consequently reducing the impact of intuitive emotional concerns.
Abstract: Should you sacrifice one man to save five? Whatever your answer, it should not depend on whether you were asked the question in your native language or a foreign tongue so long as you understood the problem. And yet here we report evidence that people using a foreign language make substantially more utilitarian decisions when faced with such moral dilemmas. We argue that this stems from the reduced emotional response elicited by the foreign language, consequently reducing the impact of intuitive emotional concerns. In general, we suggest that the increased psychological distance of using a foreign language induces utilitarianism. This shows that moral judgments can be heavily affected by an orthogonal property to moral principles, and importantly, one that is relevant to hundreds of millions of individuals on a daily basis.
293 citations
Authors
Showing all 8248 results
Name | H-index | Papers | Citations |
---|---|---|---|
Andrei Shleifer | 171 | 514 | 271880 |
Paul Elliott | 153 | 773 | 103839 |
Bert Brunekreef | 124 | 806 | 81938 |
Philippe Aghion | 122 | 507 | 73438 |
Anjana Rao | 118 | 337 | 61395 |
Jordi Sunyer | 115 | 798 | 57211 |
Kenneth J. Arrow | 113 | 411 | 111221 |
Xavier Estivill | 110 | 673 | 59568 |
Roderic Guigó | 108 | 304 | 106914 |
Mark J. Nieuwenhuijsen | 107 | 647 | 49080 |
Jordi Alonso | 107 | 523 | 64058 |
Alfonso Valencia | 106 | 542 | 55192 |
Luis Serrano | 105 | 452 | 42515 |
Vadim N. Gladyshev | 102 | 490 | 34148 |
Josep M. Antó | 100 | 493 | 38663 |