Institution
Prevention Institute
Nonprofit•Oakland, California, United States•
About: Prevention Institute is a nonprofit organization based out in Oakland, California, United States. It is known for research contribution in the topics: European Prospective Investigation into Cancer and Nutrition & Cancer. The organization has 759 authors who have published 1180 publications receiving 40555 citations.
Topics: European Prospective Investigation into Cancer and Nutrition, Cancer, Population, Breast cancer, Prospective cohort study
Papers published on a yearly basis
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James Bentham1, Mariachiara Di Cesare1, Mariachiara Di Cesare2, Gretchen A Stevens3 +787 more•Institutions (246)
TL;DR: The height differential between the tallest and shortest populations was 19-20 cm a century ago, and has remained the same for women and increased for men a century later despite substantial changes in the ranking of countries.
Abstract: Being taller is associated with enhanced longevity, and higher education and earnings. We reanalysed 1472 population-based studies, with measurement of height on more than 18.6 million participants to estimate mean height for people born between 1896 and 1996 in 200 countries. The largest gain in adult height over the past century has occurred in South Korean women and Iranian men, who became 20.2 cm (95% credible interval 17.5–22.7) and 16.5 cm (13.3–19.7) taller, respectively. In contrast, there was little change in adult height in some sub-Saharan African countries and in South Asia over the century of analysis. The tallest people over these 100 years are men born in the Netherlands in the last quarter of 20th century, whose average heights surpassed 182.5 cm, and the shortest were women born in Guatemala in 1896 (140.3 cm; 135.8–144.8). The height differential between the tallest and shortest populations was 19-20 cm a century ago, and has remained the same for women and increased for men a century later despite substantial changes in the ranking of countries.
1,348 citations
TL;DR: It is shown that the quality of evidence supporting NMA estimates varies from high to very low across comparisons, and that quality ratings given to a whole network are uninformative and likely to mislead.
Abstract: Network meta-analysis (NMA), combining direct and indirect comparisons, is increasingly being used to examine the comparative effectiveness of medical interventions. Minimal guidance exists on how to rate the quality of evidence supporting treatment effect estimates obtained from NMA. We present a four-step approach to rate the quality of evidence in each of the direct, indirect, and NMA estimates based on methods developed by the GRADE working group. Using an example of a published NMA, we show that the quality of evidence supporting NMA estimates varies from high to very low across comparisons, and that quality ratings given to a whole network are uninformative and likely to mislead.
1,138 citations
TL;DR: A wide range of human illness including lung cancer and mesothelioma in persons exposed to asbestos, leukemia in people exposed to benzene, asthma and chronic bronchitis in persons exposure to organic dusts, lung cancer in persons exposing to radon, chronic disorders of the nervous system in workers exposed to solvents, kidney failure and hypertension in persons chronically exposed to lead, heart disease in personsexposed to carbon disulfide, impairment of reproductive function in persons tested for exposure to certain Solvents and pesticides, and chronic.
Abstract: ENVIRONMENTAL and occupational diseases encompass a wide range of human illness and are important causes of disability and death in modern American society.1 , 2 They include lung cancer and mesothelioma in persons exposed to asbestos, leukemia in persons exposed to benzene, asthma and chronic bronchitis in persons exposed to organic dusts, lung cancer in persons exposed to radon, chronic disorders of the nervous system in workers exposed to solvents, kidney failure and hypertension in persons chronically exposed to lead, heart disease in persons exposed to carbon disulfide, impairment of reproductive function in persons exposed to certain solvents and pesticides, and chronic . . .
1,042 citations
University of Cambridge1, Australian National University2, Norwegian Institute of Public Health3, Utrecht University4, University of Tromsø5, The George Institute for Global Health6, Johns Hopkins University7, University of Oxford8, National Institutes of Health9, University of Copenhagen10, Copenhagen University Hospital11, Fiona Stanley Hospital12, University of Western Australia13, Harry Perkins Institute of Medical Research14, University of London15, Lund University16, University of Pittsburgh17, French Institute of Health and Medical Research18, University College London19, University of Ulm20, Technische Universität München21, University of Padua22, University of Southampton23, German Cancer Research Center24, Erasmus University Medical Center25, Umeå University26, Cardiff University27, Greifswald University Hospital28, Aarhus University29, Portland State University30, University of New South Wales31, National and Kapodistrian University of Athens32, Harvard University33, University of Hawaii34, Columbia University35, University of Iowa36, Duke University37, Yamagata University38, Tuskegee University39, University of Helsinki40, University of Oulu41, Medical University of South Carolina42, Kaiser Permanente43, University of Washington44, University of Groningen45, University of Granada46, Yale University47, Prevention Institute48, University of Edinburgh49, Uppsala University50, Basque Government51, Kyushu University52, Royal Prince Alfred Hospital53, Harokopio University54, University of California, San Diego55, VU University Medical Center56, Aalborg University57, University of Eastern Finland58, Laval University59, University of Vermont60, Wake Forest University61, Wake Forest Baptist Medical Center62, Kanazawa Medical University63, Baker IDI Heart and Diabetes Institute64, Heidelberg University65, Istituto Superiore di Sanità66, Pasteur Institute67, City College of New York68, Howard University69, University of Glasgow70, International Agency for Research on Cancer71, University of Bristol72, University of Auckland73
TL;DR: Current drinkers of alcohol in high-income countries, the threshold for lowest risk of all-cause mortality was about 100 g/week, and data support limits for alcohol consumption that are lower than those recommended in most current guidelines.
711 citations
University of Leicester1, King's College London2, Leiden University3, Imperial College London4, VU University Amsterdam5, University of Tartu6, University of Helsinki7, QIMR Berghofer Medical Research Institute8, University of Groningen9, Karolinska Institutet10, University College London11, University of Cambridge12, Erasmus University Rotterdam13, University of Leeds14, University of Georgia15, University of Oulu16, University of Oxford17, University of Washington18, National Institutes of Health19, National Institute for Health and Welfare20, National Institute for Health Research21, Wellcome Trust Centre for Human Genetics22, Georgia Regents University23, Prevention Institute24, Ludwig Maximilian University of Munich25, University of North Carolina at Chapel Hill26, University of Texas MD Anderson Cancer Center27, University of Milan28, University of Pennsylvania29, Broad Institute30, Harvard University31, Glenfield Hospital32
TL;DR: In this paper, a genome-wide meta-analysis of 37,684 individuals with replication of selected variants in an additional 10,739 individuals was carried out to identify seven loci, including five new loci associated with mean leukocyte telomere length (LTL) (P < 5 × 10−8).
Abstract: Interindividual variation in mean leukocyte telomere length (LTL) is associated with cancer and several age-associated diseases. We report here a genome-wide meta-analysis of 37,684 individuals with replication of selected variants in an additional 10,739 individuals. We identified seven loci, including five new loci, associated with mean LTL (P < 5 × 10(-8)). Five of the loci contain candidate genes (TERC, TERT, NAF1, OBFC1 and RTEL1) that are known to be involved in telomere biology. Lead SNPs at two loci (TERC and TERT) associate with several cancers and other diseases, including idiopathic pulmonary fibrosis. Moreover, a genetic risk score analysis combining lead variants at all 7 loci in 22,233 coronary artery disease cases and 64,762 controls showed an association of the alleles associated with shorter LTL with increased risk of coronary artery disease (21% (95% confidence interval, 5-35%) per standard deviation in LTL, P = 0.014). Our findings support a causal role of telomere-length variation in some age-related diseases.
703 citations
Authors
Showing all 772 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Veikko Salomaa | 162 | 843 | 135046 |
| Paolo Vineis | 134 | 1088 | 86608 |
| Antonia Trichopoulou | 133 | 944 | 84874 |
| Domenico Palli | 128 | 887 | 71478 |
| Osamu Takeuchi | 116 | 288 | 90116 |
| George A. Mensah | 114 | 450 | 151498 |
| Harold Snieder | 104 | 553 | 46629 |
| Tom Baranowski | 103 | 485 | 36327 |
| Junji Yodoi | 98 | 506 | 36302 |
| Esther M. John | 96 | 476 | 33679 |
| Burkhardt Seifert | 83 | 566 | 28368 |
| Giovanna Masala | 78 | 442 | 18508 |
| Ann W. Hsing | 78 | 307 | 22817 |
| Sabine Rohrmann | 75 | 370 | 18376 |
| Milo A. Puhan | 72 | 404 | 22802 |