Purdue University

About: Purdue University is a education organization based out in West Lafayette, Indiana, United States. It is known for research contribution in the topics: Population & Heat transfer. The organization has 73219 authors who have published 163563 publications receiving 5775236 citations. The organization is also known as: Purdue & Purdue-West Lafayette.

Annonaceous Acetogenins: Recent Progress

Abstract: The Annonaceous acetogenins are promising new antitumor and pesticidal agents that are found only in the plant family Annonaceae. Chemically, they are derivatives of long-chain fatty acids. Biologically, they exhibit their potent bioactivities through depletion of ATP levels via inhibiting complex I of mitochondria and inhibiting the NADH oxidase of plasma membranes of tumor cells. Thus, they thwart ATP-driven resistance mechanisms. This review presents the progress made in the chemistry, biology, and development of these compounds since December 1995.

Cyberball : A program for use in research on interpersonal ostracism and acceptance

Abstract: Since the mid-1990s, research on interpersonal acceptance and exclusion has proliferated, and several paradigms have evolved that vary in their efficiency, context specificity, and strength. This article describes one such paradigm, Cyberball, which is an ostensibly online ball-tossing game that participants believe they are playing with two or three others. In fact, the “others” are controlled by the programmer. The course and speed of the game, the frequency of inclusion, player information, and iconic representation are all options the researcher can regulate. The game was designed to manipulate independent variables (e.g., ostracism) but can also be used as a dependent measure of prejudice and discrimination. The game works on both PC and Macintosh (OS X) platforms and is freely available.

Genetic mechanisms of abiotic stress tolerance that translate to crop yield stability.

Abstract: Crop yield reduction as a consequence of increasingly severe climatic events threatens global food security. Genetic loci that ensure productivity in challenging environments exist within the germplasm of crops, their wild relatives and species that are adapted to extreme environments. Selective breeding for the combination of beneficial loci in germplasm has improved yields in diverse environments throughout the history of agriculture. An effective new paradigm is the targeted identification of specific genetic determinants of stress adaptation that have evolved in nature and their precise introgression into elite varieties. These loci are often associated with distinct regulation or function, duplication and/or neofunctionalization of genes that maintain plant homeostasis.

Modeling relationship strength in online social networks

Abstract: Previous work analyzing social networks has mainly focused on binary friendship relations. However, in online social networks the low cost of link formation can lead to networks with heterogeneous relationship strengths (e.g., acquaintances and best friends mixed together). In this case, the binary friendship indicator provides only a coarse representation of relationship information. In this work, we develop an unsupervised model to estimate relationship strength from interaction activity (e.g., communication, tagging) and user similarity. More specifically, we formulate a link-based latent variable model, along with a coordinate ascent optimization procedure for the inference. We evaluate our approach on real-world data from Facebook and LinkedIn, showing that the estimated link weights result in higher autocorrelation and lead to improved classification accuracy.