Purdue University

About: Purdue University is a education organization based out in West Lafayette, Indiana, United States. It is known for research contribution in the topics: Population & Heat transfer. The organization has 73219 authors who have published 163563 publications receiving 5775236 citations. The organization is also known as: Purdue & Purdue-West Lafayette.

Neurons in the Rat Dentate Gyrus Granular Layer Substantially Increase During Juvenile and Adult Life

Abstract: Volumetric estimates of the total number of granule cells in rats 30, 120, 200, and 365 days old increase linearly by approximately 35 to 43 percent between 1 month and 1 year. Total volume of the granular layer also grows linearly during that time. These results demonstrate a numerical increase in a neuronal population during adulthood in the mammalian brain.

Goal and Self-Evaluative Influences During Children’s Cognitive Skill Learning

Abstract: Two studies investigated how goals and self-evaluation affect motivation and achievement outcomes. In both studies, fourth-grade students received instruction and practice on fractions over sessions. Students worked under conditions involving either a goal of learning how to solve problems (learning goal) or a goal of merely solving them (performance goal). In Study 1, half of the students in each goal condition evaluated their problem-solving capabilities. The learning goal with or without self-evaluation and the performance goal with self-evaluation led to higher self-efficacy, skill, motivation, and task orientation than did the performance goal without self-evaluation. In Study 2, all students in each goal condition evaluated their progress in skill acquisition. The learning goal led to higher motivation and achievement outcomes than did the performance goal. Research suggestions and implications for educational practice are discussed.

A protein catalytic framework with an N-terminal nucleophile is capable of self-activation

Abstract: The crystal structures of three amidohydrolases have been determined recently: glutamine PRPP amidotransferase (GAT), penicillin acylase, and the proteasome. These enzymes use the side chain of the amino-terminal residue, incorporated in a beta-sheet, as the nucleophile in the catalytic attack at the carbonyl carbon. The nucleophile is cysteine in GAT, serine in penicillin acylase, and threonine in the proteasome. Here we show that all three enzymes share an unusual fold in which the nucleophile and other catalytic groups occupy equivalent sites. This fold provides both the capacity for nucleophilic attack and the possibility of autocatalytic processing. We suggest the name Ntn (N-terminal nucleophile) hydrolases for this structural superfamily of enzymes which appear to be evolutionarily related but which have diverged beyond any recognizable sequence similarity.

Evidence from d + Au measurements for final state suppression of high p(T) hadrons in Au+Au collisions at RHIC

Abstract: We report measurements of single-particle inclusive spectra and two-particle azimuthal distributions of charged hadrons at high transverse momentum (high p(T)) in minimum bias and central d+Au collisions at sqrt[s(NN)]=200 GeV. The inclusive yield is enhanced in d+Au collisions relative to binary-scaled p+p collisions, while the two-particle azimuthal distributions are very similar to those observed in p+p collisions. These results demonstrate that the strong suppression of the inclusive yield and back-to-back correlations at high p(T) previously observed in central Au+Au collisions are due to final-state interactions with the dense medium generated in such collisions.