Purdue University

About: Purdue University is a education organization based out in West Lafayette, Indiana, United States. It is known for research contribution in the topics: Population & Context (language use). The organization has 73219 authors who have published 163563 publications receiving 5775236 citations. The organization is also known as: Purdue & Purdue-West Lafayette.

Analysis of a denial of service attack on TCP

Abstract: The paper analyzes a network based denial of service attack for IP (Internet Protocol) based networks. It is popularly called SYN flooding. It works by an attacker sending many TCP (Transmission Control Protocol) connection requests with spoofed source addresses to a victim's machine. Each request causes the targeted host to instantiate data structures out of a limited pool of resources. Once the target host's resources are exhausted, no more incoming TCP connections can be established, thus denying further legitimate access. The paper contributes a detailed analysis of the SYN flooding attack and a discussion of existing and proposed countermeasures. Furthermore, we introduce a new solution approach, explain its design, and evaluate its performance. Our approach offers protection against SYN flooding for all hosts connected to the same local area network, independent of their operating system or networking stack implementation. It is highly portable, configurable, extensible, and requires neither special hardware, nor modifications in routers or protected end systems.

The Genetics of Lignin Biosynthesis: Connecting Genotype to Phenotype

Abstract: The processes underlying lignification, which for many years have been the near-exclusive purview of chemists and biochemists, have more recently been approached using both classical forward genetic screens and targeted reverse genetic approaches such as antisense suppression, RNAi, and characterization of insertional mutants. In this review, we provide an overview of the current understanding of lignin biosynthesis and structure, with emphasis on mutant and transgenic plants that have contributed to this knowledge. We also discuss ongoing work aimed at elucidating the relationship between lignin structure and function in vivo, as well as the phenotypic consequences arising from genetic manipulation of the lignin biosynthetic pathway.

Vibrational spectroscopic imaging of living systems: An emerging platform for biology and medicine

Abstract: Vibrational spectroscopy has been extensively applied to the study of molecules in gas phase, in condensed phase, and at interfaces. The transition from spectroscopy to spectroscopic imaging of living systems, which allows the spectrum of biomolecules to act as natural contrast, is opening new opportunities to reveal cellular machinery and to enable molecule-based diagnosis. Such a transition, however, involves more than a simple combination of spectrometry and microscopy. We review recent efforts that have pushed the boundary of the vibrational spectroscopic imaging field in terms of spectral acquisition speed, detection sensitivity, spatial resolution, and imaging depth. We further highlight recent applications in functional analysis of single cells and in label-free detection of diseases.