Queensland University of Technology

About: Queensland University of Technology is a education organization based out in Brisbane, Queensland, Australia. It is known for research contribution in the topics: Population & Context (language use). The organization has 14188 authors who have published 55022 publications receiving 1496237 citations. The organization is also known as: QUT.

Electrospinning and additive manufacturing: converging technologies

Abstract: A well-engineered scaffold for regenerative medicine, which is suitable to be translated from the bench to the bedside, combines inspired design, technical innovation and precise craftsmanship. Electrospinning and additive manufacturing are separate approaches to manufacturing scaffolds for a variety of tissue engineering applications. A need to accurately control the spatial distribution of pores within scaffolds has recently resulted in combining the two processing methods, to overcome shortfalls in each technology. This review describes where electrospinning and additive manufacturing are used together to generate new porous structures for biological applications.

Taxonomy of the order Mononegavirales: update 2017

Abstract: In 2017, the order Mononegavirales was expanded by the inclusion of a total of 69 novel species. Five new rhabdovirus genera and one new nyamivirus genus were established to harbor 41 of these species, whereas the remaining new species were assigned to already established genera. Furthermore, non-Latinized binomial species names replaced all paramyxovirus and pneumovirus species names, thereby accomplishing application of binomial species names throughout the entire order. This article presents the updated taxonomy of the order Mononegavirales as now accepted by the International Committee on Taxonomy of Viruses (ICTV).

An integrative multi-omics analysis to identify candidate DNA methylation biomarkers related to prostate cancer risk.

Abstract: It remains elusive whether some of the associations identified in genome-wide association studies of prostate cancer (PrCa) may be due to regulatory effects of genetic variants on CpG sites, which may further influence expression of PrCa target genes. To search for CpG sites associated with PrCa risk, here we establish genetic models to predict methylation (N = 1,595) and conduct association analyses with PrCa risk (79,194 cases and 61,112 controls). We identify 759 CpG sites showing an association, including 15 located at novel loci. Among those 759 CpG sites, methylation of 42 is associated with expression of 28 adjacent genes. Among 22 genes, 18 show an association with PrCa risk. Overall, 25 CpG sites show consistent association directions for the methylation-gene expression-PrCa pathway. We identify DNA methylation biomarkers associated with PrCa, and our findings suggest that specific CpG sites may influence PrCa via regulating expression of candidate PrCa target genes.

A Multidimensional Definition of Partner Abuse: Development and Preliminary Validation of the Composite Abuse Scale

Abstract: The lack of definitional consistency about domestic violence and the absence of a well-validated comprehensive abuse screening questionnaire have been major methodological flaws in domestic violence research. While there are several screening questionnaires in use, they either are narrowly defined and do not have discrete measures of physical, emotional, and sexual abuse or have not been validated on both abused and nonabused samples. This study presents the development and preliminary validation of a new partner abuse screening questionnaire (Composite Abuse Scale; CAS). Items measuring the three areas of partner abuse were extracted from four published scales: the Conflict Tactics Scale, Measure of Wife Abuse, Inventory of Spouse Abuse, and Psychological Maltreatment of Women Inventory. A survey using these items was sent to all nurses working at a large Australian public, inner-city teaching hospital. Factor analyses of the responses of 427 participants revealed four dimensions: Severe Combined Abuse, Emotional Abuse, Physical Abuse, and Harassment. Preliminary evidence is presented on validity and a high scale reliability is reported for each subscale.

Experimental procedure for the manufacture and calibration of polyacrylamide gel (PAG) for magnetic resonance imaging (MRI) radiation dosimetry

Abstract: A simple methodology for the manufacture and calibration of polyacrylamide gel (PAG) for magnetic resonance imaging (MRI) radiation dosimetry is presented to enable individuals to undertake such work in a routine clinical environment. Samples of PAG were irradiated using a linear accelerator and imaged using a 0.5 T (22 MHz) Philips Gyroscan MRI scanner. The mean spin-lattice relaxation rate was measured using a `turbo-mixed' sequence, consisting of a series of pulses, each followed by acquisition of a train of spin echoes. The mean sensitivity for five different batches of PAG in the range up to 10 Gy was calculated to be for the mean spin-lattice relaxation rate with a percentage standard deviation of 1.25%. The overall reproducibility between batches was calculated to be 2.69%. This methodology, which introduces the novel use of pre-filled nitrogen vials for calibration, has been used to develop techniques for filling anatomically shaped anthropomorphic phantoms.