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Institution

Research Triangle Park

NonprofitDurham, North Carolina, United States
About: Research Triangle Park is a nonprofit organization based out in Durham, North Carolina, United States. It is known for research contribution in the topics: Population & Environmental exposure. The organization has 24961 authors who have published 35800 publications receiving 1684504 citations. The organization is also known as: RTP.


Papers
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Journal ArticleDOI
TL;DR: The new GSK Solvent Sustainability Guide enables GSK scientists to objectively assess solvents and facilitates both comparison of individual sustainability criteria, and a composite score and colour for rank ordering, incorporating multiple facets of sustainability.

475 citations

Journal ArticleDOI
TL;DR: This article investigated the effect of BPA on the immature rat uterus and found that BPA antagonized the E2 stimulatory effects on both peroxidase activity and PR levels but did not inhibit E2-induced increases of uterine weight.

475 citations

Journal ArticleDOI
TL;DR: To obtain estimates of the frequency of nosocomial infections nationwide, those occurring at the four major sites--urinary tract, surgical wound, lower respiratory tract and bloodstream--were diagnosed in a stratified random sample of 169,526 adult, general medical and surgical patients selected from 338 hospitals representative of the "mainstream" of U.S. hospitals.

475 citations

Journal ArticleDOI
TL;DR: The authors examined the extent to which variation in observed classroom supports (quality of emotional and instructional interactions and amount of exposure to literacy and math activities) predicts trajectories of achievement in reading and math from 54 months to fifth grade.
Abstract: This nonexperimental, longitudinal field study examines the extent to which variation in observed classroom supports (quality of emotional and instructional interactions and amount of exposure to literacy and math activities) predicts trajectories of achievement in reading and math from 54 months to fifth grade. Growth mixture modeling detected two latent classes of readers: fast readers whose skills developed rapidly and leveled off, and a typical group for which reading growth was somewhat less rapid. Only one latent class was identified for math achievement. For reading, there were small positive associations between observed emotional quality of teacher-child interactions and growth. Growth in math achievement showed small positive relations with observed emotional interactions and exposure to math activities. There was a significant interaction between quality and quantity of instruction for reading such that at higher levels of emotional quality there was less of a negative association between amoun...

474 citations

Journal ArticleDOI
TL;DR: The role of SA and JA signaling in influencing O3-induced cell death has been confirmed and an antagonistic relationship between JA- and SA-signaling pathways in controlling the magnitude of O2-induced HR-like cell death is demonstrated.
Abstract: Recent studies suggest that cross-talk between salicylic acid (SA)‐, jasmonic acid (JA)‐, and ethylene-dependent signaling pathways regulates plant responses to both abiotic and biotic stress factors. Earlier studies demonstrated that ozone (O 3 ) exposure activates a hypersensitive response (HR)‐like cell death pathway in the Arabidopsis ecotype Cvi-0. We now have confirmed the role of SA and JA signaling in influencing O 3 -induced cell death. Expression of salicylate hydroxylase (NahG) in Cvi-0 reduced O 3 -induced cell death. Methyl jasmonate (Me-JA) pretreatment of Cvi-0 decreased O 3 -induced H 2 O 2 content and SA concentrations and completely abolished O 3 -induced cell death. Cvi-0 synthesized as much JA as did Col-0 in response to O 3 exposure but exhibited much less sensitivity to exogenous Me-JA. Analyses of the responses to O 3 of the JA-signaling mutants jar1 and fad3/7/8 also demonstrated an antagonistic relationship between JA- and SA-signaling pathways in controlling the magnitude of O 3 -induced HR-like cell death.

473 citations


Authors

Showing all 25006 results

NameH-indexPapersCitations
Douglas G. Altman2531001680344
Lewis C. Cantley196748169037
Ronald Klein1941305149140
Daniel J. Jacob16265676530
Christopher P. Cannon1511118108906
James B. Meigs147574115899
Lawrence Corey14677378105
Jeremy K. Nicholson14177380275
Paul M. Matthews14061788802
Herbert Y. Meltzer137114881371
Charles J. Yeo13667276424
Benjamin F. Cravatt13166661932
Timothy R. Billiar13183866133
Peter Brown12990868853
King K. Holmes12460656192
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202317
202277
2021988
20201,001
20191,035
20181,051