Rio de Janeiro State University

About: Rio de Janeiro State University is a education organization based out in Rio de Janeiro, Brazil. It is known for research contribution in the topics: Population & Large Hadron Collider. The organization has 16631 authors who have published 30919 publications receiving 465753 citations. The organization is also known as: UERJ & Rio de Janeiro State University.

Clinical and biochemical study of 28 patients with mucopolysaccharidosis type VI.

Abstract: This paper presents data collected by a Brazilian center in a multinational multicenter observational study of patients with mucopolysaccharidosis type VI (MPS VI), aiming at determining the epidemiological, clinical, and biochemical profile of these patients. Twenty-eight south-American patients with MPS VI were evaluated through medical interview, physical exam, echocardiogram, electrocardiogram, ophthalmologic evaluation, quantification of glycosaminoglycans (GAGs) in urine, and measurement of the activity of N-acetylgalactosamine-4-sulfatase (ARSB) in leukocytes. 92.9% of patients were Brazilian. Mean age at diagnosis and at evaluation was 48.4 months and 97.1 months, respectively. 88% of patients had onset of symptomatology before the age of 36 months. Consanguinity was reported by 27% of the families. Mean weight and height at birth were 3.481 kg and 51.3 cm, respectively. The most frequently reported clinical manifestations were short stature, corneal clouding, coarse facial features, joint contractures, and claw hands. All patients presented with echocardiogram changes as well as corneal clouding. Mean ARSB activity in leukocytes was 5.4 nmoles/h/mg protein (reference values: 72-174), and urinary excretion of GAGs was on average 7.9 times higher than normal. The number of clinical manifestations did not show a significant correlation with the levels of urinary GAGs nor with the ARSB activity. Also, no significant correlation was found between the levels of urinary GAGs and the ARSB activity. It was concluded that MPS VI has high morbidity and that, when compared with data published in the literature, patients in our study were diagnosed later and presented with a higher frequency of cardiological findings.

Study of Z boson production in PbPb collisions at √s NN=2.76TeV

Abstract: A search for Z bosons in the mu^+mu^- decay channel has been performed in PbPb collisions at a nucleon-nucleon centre of mass energy = 2.76 TeV with the CMS detector at the LHC, in a 7.2 inverse microbarn data sample. The number of opposite-sign muon pairs observed in the 60--120 GeV/c^2 invariant mass range is 39, corresponding to a yield per unit of rapidity (y) and per minimum bias event of (33.8 +/- 5.5 (stat) +/- 4.4 (syst)) 10^{-8}, in the |y|<2.0 range. Rapidity, transverse momentum, and centrality dependencies are also measured. The results agree with next-to-leading order QCD calculations, scaled by the number of incoherent nucleon-nucleon collisions.

MTA versus Portland cement as repair material for furcal perforations: a laboratory study using a polymicrobial leakage model

Abstract: De-Deus G, Petruccelli V, Gurgel-Filho E, CoutinhoFilho T. MTA versus Portland cement as repair material for furcal perforations: a laboratory study using a polymicrobial leakage model. International Endodontic Journal, 39, 293–298, 2006. Aim To compare the ability of Portland cement and mineral trioxide aggregate (MTA) to prevent coronal leakage through repaired furcal perforations in molar teeth. Methodology The pulp chambers of 36 human mandibular molar teeth were accessed and the root canal orifices were located. The roots were horizontally sectioned in the middle third. Composite resin was used to fill the root canal orifices and the apical end of the roots. Perforations were created in the centre of the pulp chamber floor using a size 3 round bur. Thirty teeth were divided into two groups (n ¼ 15) and a further six teeth served as controls. In G1, all 15 perforation defects were repaired with MTA while in G2, Portland cement was used. Each tooth was inserted in a silicone tube (bacterial reservoir) with the region containing the perforation protruding through the end. The system was sterilized and placed in a glass flask containing sterile brain heart infusion medium (BHI). The reservoirs were filled with human saliva mixed in BHI and system was incubated at 37 � C and checked daily for the appearance of turbidity in the BHI broth during the following 50 days. The leakage data were analysed statistically by a log-rank test (P 0.05). Conclusion Portland cement and MTA demonstrated a similar ability to seal furcal perforations.

Ability to sit and rise from the floor as a predictor of all-cause mortality

Abstract: Background:While cardiorespiratory fitness is strongly related to survival, there are limited data regarding musculoskeletal fitness indicators. Our aim was to evaluate the association between the ability to sit and rise from the floor and all-cause mortality.Design:Retrospective cohort.Methods:2002 adults aged 51–80 years (68% men) performed a sitting-rising test (SRT) to and from the floor, which was scored from 0 to 5, with one point being subtracted from 5 for each support used (hand/knee). Final SRT score, varying from 0 to 10, was obtained by adding sitting and rising scores and stratified in four categories for analysis: 0–3; 3.5–5.5, 6–7.5, and 8–10.Results:Median follow up was 6.3 years and there were 159 deaths (7.9%). Lower SRT scores were associated with higher mortality (p < 0.001). A continuous trend for longer survival was reflected by multivariate-adjusted (age, sex, body mass index) hazard ratios of 5.44 (95% CI 3.1–9.5), 3.44 (95% CI 2.0–5.9), and 1.84 (95% CI 1.1–3.0) (p < 0.001) from l...