Roma Tre University

About: Roma Tre University is a education organization based out in Rome, Lazio, Italy. It is known for research contribution in the topics: Large Hadron Collider & Galaxy. The organization has 4434 authors who have published 15352 publications receiving 374888 citations. The organization is also known as: Universita degli Studi Roma Tre & RomaTre.

Layout and performance of RPCs used in the Argo-YBJ experiment

Abstract: The layout of the RPCs, used in the Argo-YBJ experiment to image with a high space-time granularity the atmospheric shower, is described in this paper. The detector has been assembled to provide both digital and analog informations in order to cover a wide particle density range with a time accuracy of 1 ns. The experimental results obtained operating the chambers in streamer mode at sea level with a standard gas mixture are presented.

Chandra unveils a binary Active Galactic Nucleus in Mrk 463

Abstract: We analyse Chandra, XMM‐Newton and Hubble Space Telescope (HST) data of the doublenucleus Ultraluminous Infrared Galaxy (ULIRG), Mrk 463. The Chandra detection of two luminous (L2‐10 keV = 1.5 × 10 43 and 3.8 × 10 42 erg cm −2 s −1 ), unresolved nuclei in Mrk 463 indicates that this galaxy hosts a binary active galactic nucleus (AGN), with a projected separation of � 3.8 kpc (3.83 ± 0.01 arcsec). While the East nucleus was already known to be a type 2 Seyfert (and this is further confirmed by our Chandra detection of a neutral iron line), this is the first unambiguous evidence in favour of the AGN nature of the West nucleus. Mrk 463 is therefore the clearest case so far for a binary AGN, after NGC 6240.

The Bovine Basic Pancreatic Trypsin Inhibitor (Kunitz Inhibitor): A Milestone Protein

Abstract: The pancreatic Kunitz inhibitor, also known as aprotinin, bovine basic pancreatic trypsin inhibitor (BPTI), and trypsin-kallikrein inhibitor, is one of the most extensively studied globular proteins. It has proved to be a particularly attractive and powerful tool for studying protein conformation as well as molecular bases of protein/protein interaction(s) and (macro)molecular recognition. BPTI has a relatively broad specificity, inhibiting trypsin- as well as chymotrypsin- and elastase-like serine (pro)enzymes endowed with very different primary specificity. BPTI reacts rapidly with serine proteases to form stable complexes, but the enzyme: inhibitor complex formation may involve several intermediates corresponding to discrete reaction steps. Moreover, BPTI inhibits the nitric oxide synthase type-I and -II action and impairs K+ transport by Ca2+-activated K+ channels. Clinically, the use of BPTI in selected surgical interventions, such as cardiopulmonary surgery and orthotopic liver transplantation, is advised, as it significantly reduces hemorrhagic complications and thus blood-transfusion requirements. Here, the structural, inhibition, and bio-medical aspects of BPTI are reported.

Glass fabric reinforced cementitious matrix: Tensile properties and bond performance on masonry substrate

Abstract: Fibre-reinforced composite materials have gained an increasing success, mostly for strengthening, retrofitting, and repairing existing structures. However some problems may arise with the use of traditional FRP (Fiber Reinforced Polymer), particularly when the compatibility with the substrate and the reversibility of the intervention are required, as in case of cultural heritage buildings, or specific exposition conditions may compromise the long term effectiveness of the reinforcement, as in presence of high temperature and humidity. Starting from these considerations new composite materials are emerging as a more effective solution in certain fields of application and under specific service conditions; in this context, mortar-based composite systems, consisting of one or more layers of uni- or bi-directional fibre nets embedded in cement/lime-based matrix layers, can be used as reinforcement of both concrete and masonry structures. However, the research work dealing with these emerging materials and their performances when used as a strengthening system for existing structures is still limited. Both experimental and theoretical investigations are needed in order to deliver reliable design methodologies. In this work, a Round Robin Test aimed to the characterization of both bond with the existing substrate and tensile performance of glass fabric (in the form of grids) coupled with inorganic mortar matrices is presented. The investigation was conducted at fifteen laboratories involved in the RILEM Technical Committee 250-CSM (Composites for the Sustainable Strengthening of Masonry). With the aim of studying the bond behaviour between Fabric Reinforced Cementitious Matrix (FRCM) composites and masonry substrate, single and double lap shear tests were carried out on brick-masonry prisms. Results provide useful informations about the mechanical properties, the bond capacity and the failure mechanisms of different commercially available glass FRCM systems. Finally, critical aspects are underlined to address the progress of the research work.

Integrating train scheduling and delay management in real-time railway traffic control

Abstract: Optimization models for railway traffic rescheduling tackle the problem of determining, in real-time, control actions to reducing the effect of disturbances in railway systems. In this field, mainly two research streams can be identified. On the one hand, train scheduling models are designed to include all conditions relevant to feasible and efficient operation of rail services, from the viewpoint of operations managers. On the other hand, delay management models focus on the impact of rescheduling decisions on the quality of service perceived by the passengers. Models in the first stream are mainly microscopic, while models in the second stream are mainly macroscopic. This paper aims at merging these two streams of research by developing microscopic passenger-centric models, solution algorithms and lower bounds. Several fast heuristic methods are proposed, based on alternative decompositions of the model. A lower bound is proposed, consisting of the resolution of a set of min-cost flow problems with activation constraints. Computational experiments, based on multiple test cases of the real-world Dutch railway network, show that good quality solutions and lower bounds can be found within a limited computation time.