Institution
Rush University Medical Center
Healthcare•Chicago, Illinois, United States•
About: Rush University Medical Center is a healthcare organization based out in Chicago, Illinois, United States. It is known for research contribution in the topics: Population & Dementia. The organization has 13915 authors who have published 29027 publications receiving 1379216 citations. The organization is also known as: Rush Presbyterian St. Luke's Medical Center.
Topics: Population, Dementia, Transplantation, Cognitive decline, Health care
Papers published on a yearly basis
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TL;DR: It is demonstrated that hippocampal neurogenesis is persistent through the tenth decade of life and is detectable in patients with mild cognitive impairments and Alzheimer's disease and that it is possibly associated with cognition.
356 citations
TL;DR: It is argued that ageing induces a pre-parkinsonian state, and that the cellular mechanisms of dopamine neuron demise during normal ageing are accelerated or exaggerated in Parkinson's disease through a combination of genetic and environmental factors.
Abstract: Ageing is the greatest risk factor for the development of Parkinson's disease. However, the current dogma holds that cellular mechanisms that are associated with ageing of midbrain dopamine neurons and those that are related to dopamine neuron degeneration in Parkinson's disease are unrelated. We propose, based on evidence from studies of non-human primates, that normal ageing and the degeneration of dopamine neurons in Parkinson's disease are linked by the same cellular mechanisms and, therefore, that markers of cellular risk factors accumulate with age in a pattern that mimics the pattern of degeneration observed in Parkinson's disease. We contend that ageing induces a pre-parkinsonian state, and that the cellular mechanisms of dopamine neuron demise during normal ageing are accelerated or exaggerated in Parkinson's disease through a combination of genetic and environmental factors.
355 citations
University of California, Los Angeles1, King's College London2, University of Florida3, Washington University in St. Louis4, Abbott Northwestern Hospital5, University of Michigan6, University of Kansas7, Columbia University Medical Center8, Indiana University9, Overlook Medical Center10, University of Rochester Medical Center11, Rush University Medical Center12, Rutgers University13, University of Cincinnati14, Hackensack University Medical Center15, University of California, Irvine16, Winthrop-University Hospital17, Rhode Island Hospital18, University of Colorado Hospital19, Henry Ford Health System20, University of Texas Health Science Center at San Antonio21, University of Pennsylvania22, University of North Carolina at Chapel Hill23, City of Hope National Medical Center24, Thomas Jefferson University25, St. Joseph Hospital26, Vanderbilt University27, Beth Israel Deaconess Medical Center28, Baylor University Medical Center29, Medical University of South Carolina30, Mount Sinai Hospital31, Dresden University of Technology32, Tufts University33, Stony Brook University34, Université de Sherbrooke35, University of California, San Diego36, Houston Methodist Hospital37, Geisinger Health System38, Kaiser Permanente39, University of Kentucky40, Montreal Neurological Institute and Hospital41, Hofstra University42, University of Washington43, Northwest Biotherapeutics44
TL;DR: Addition of DCVax-L to standard therapy is feasible and safe in glioblastoma patients, and may extend survival, and overall adverse events withDCVax were comparable to standard Therapy alone.
Abstract: Following publication of the original article [1], the authors reported an error in the spelling of one of the author names. In this Correction the incorrect and correct author names are indicated and the author name has been updated in the original publication. The authors also reported an error in the Methods section of the original article. In this Correction the incorrect and correct versions of the affected sentence are indicated. The original article has not been updated with regards to the error in the Methods section.
355 citations
TL;DR: Baseline proteinuria is an important risk factor for kidney failure and provides a means to identify patients at greatest risk and proteinuria reduction using an angiotensin receptor-blocking agent, such as irbesartan, should be regarded as an important therapeutic goal in renoprotective strategies.
354 citations
TL;DR: Findings suggest that frailty and AD may share similar etiologies, and increasing frailty is associated with incident AD and the rate of cognitive decline in older persons.
Abstract: Objective:To assess the association between frailty and incident Alzheimer’s disease (AD) and cognitive decline. Frailty is common in older persons and associated with adverse health outcomes.Methods:Study subjects included 823 older persons without dementia who participated in the Rush Memory and A
354 citations
Authors
Showing all 14032 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| John Q. Trojanowski | 226 | 1467 | 213948 |
| Virginia M.-Y. Lee | 194 | 993 | 148820 |
| Luigi Ferrucci | 193 | 1601 | 181199 |
| David A. Bennett | 167 | 1142 | 109844 |
| Todd R. Golub | 164 | 422 | 201457 |
| David Cella | 156 | 1258 | 106402 |
| M.-Marsel Mesulam | 150 | 558 | 90772 |
| John D. E. Gabrieli | 142 | 480 | 68254 |
| David J. Kupfer | 141 | 862 | 102498 |
| Clifford B. Saper | 136 | 406 | 72203 |
| Pasi A. Jänne | 136 | 685 | 89488 |
| Nikhil C. Munshi | 134 | 906 | 67349 |
| Martin B. Keller | 131 | 541 | 65069 |
| Michael E. Thase | 131 | 923 | 75995 |
| Steven R. Simon | 129 | 1090 | 80331 |