Institution
Rush University Medical Center
Healthcare•Chicago, Illinois, United States•
About: Rush University Medical Center is a healthcare organization based out in Chicago, Illinois, United States. It is known for research contribution in the topics: Population & Dementia. The organization has 13915 authors who have published 29027 publications receiving 1379216 citations. The organization is also known as: Rush Presbyterian St. Luke's Medical Center.
Topics: Population, Dementia, Transplantation, Cognitive decline, Health care
Papers published on a yearly basis
Papers
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TL;DR: Two error measures, the percentage area misclassified and a new pixel distance error, were defined and evaluated in terms of their correlation with human observation for comparison of multiple segmentations of the same scene and multiple scenes segmented by the same technique.
342 citations
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Washington University in St. Louis1, Brigham Young University2, Baylor College of Medicine3, Broad Institute4, Rush University Medical Center5, University of Pennsylvania6, Cardiff University7, Vanderbilt University8, Columbia University9, John P. Hussman Institute for Human Genomics10, Boston University11, Veterans Health Administration12, University of California, San Diego13
TL;DR: In independent data sets, rs9877502 showed a strong association with risk for AD, tangle pathology, and global cognitive decline, illustrating how this endophenotype-based approach can be used to identify new AD risk loci.
340 citations
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TL;DR: In this study, E5 did not reduce mortality in nonshock patients with Gram-negative sepsis whether or not those patients also had organ failure, but E5did result in greater resolution of organ failure in patients with gram-negative Sepsis and E5 resulted in the prevention of adult respiratory distress syndrome and central nervous system organ failure.
Abstract: ObjectiveTo evaluate the safety and efficacy of E5, a murine, monoclonal antibody directed against endotoxin, in the treatment of patients with Gram-negative sepsis.DesignA multicenter, randomized, double-blind, placebo-controlled trial.SettingFifty-three hospitals across the United States, includin
339 citations
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TL;DR: It is critical to evaluate all patients with recurrent shoulder instability for the presence of osseous injuries to the glenoids, and a careful preoperative evaluation to diagnose and quantify anterior glenoid deficiency is crucial for the success of surgical treatment.
Abstract: Recurrent instability of the glenohumeral joint is usually associated with a Bankart tear—a soft-tissue injury of the glenoid labrum attachment. However, patients with recurrent shoulder instability often present with osseous injury to the glenoid and humeral head as well. Understanding and appropriately addressing irregularities in the osseous architecture of the glenohumeral joint are critical to the overall success of surgical repair for the treatment of glenohumeral instability1. The integrity of the osseous architecture of the glenoid has recently been highlighted as one of the most important factors related to the success of surgical repair2,3. After the initial traumatic shoulder dislocation, an associated glenoid rim fracture or attritional bone injury may compromise the static restraints of the glenohumeral joint, making further instability more likely. With recurrent instability, there can be further attritional glenoid bone loss.
Glenoid bone deficiency with recurrent shoulder instability is an increasingly recognized cause of failed shoulder stabilization surgery. It is critical to evaluate all patients with recurrent shoulder instability for the presence of osseous injuries to the glenoid. Specific findings in the history and the physical examination provide important clues to the presence of glenoid bone loss, and a careful preoperative evaluation to diagnose and quantify anterior glenoid deficiency is crucial for the success of surgical treatment.
Appropriate preoperative imaging is essential for detection and quantification of osseous abnormalities in patients with recurrent shoulder instability. The apical oblique view described by Garth et al.4, the West Point view5, and the Didiee view6 are recognized as being the most sensitive radiographs for detecting osseous abnormalities of the glenoid. Magnetic resonance imaging and magnetic resonance arthrography may be used, but they are primarily employed to assess the surrounding soft tissues. If any osseous lesion is discovered on radiographs, …
339 citations
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TL;DR: This review aims to summarize recent progress and describe how this new work informs the understanding of sleep regulation and sleep behavior during this developmental time frame.
339 citations
Authors
Showing all 14032 results
Name | H-index | Papers | Citations |
---|---|---|---|
John Q. Trojanowski | 226 | 1467 | 213948 |
Virginia M.-Y. Lee | 194 | 993 | 148820 |
Luigi Ferrucci | 193 | 1601 | 181199 |
David A. Bennett | 167 | 1142 | 109844 |
Todd R. Golub | 164 | 422 | 201457 |
David Cella | 156 | 1258 | 106402 |
M.-Marsel Mesulam | 150 | 558 | 90772 |
John D. E. Gabrieli | 142 | 480 | 68254 |
David J. Kupfer | 141 | 862 | 102498 |
Clifford B. Saper | 136 | 406 | 72203 |
Pasi A. Jänne | 136 | 685 | 89488 |
Nikhil C. Munshi | 134 | 906 | 67349 |
Martin B. Keller | 131 | 541 | 65069 |
Michael E. Thase | 131 | 923 | 75995 |
Steven R. Simon | 129 | 1090 | 80331 |