Rush University Medical Center

About: Rush University Medical Center is a healthcare organization based out in Chicago, Illinois, United States. It is known for research contribution in the topics: Population & Medicine. The organization has 13915 authors who have published 29027 publications receiving 1379216 citations. The organization is also known as: Rush Presbyterian St. Luke's Medical Center.

Total hip arthroplasty using the minimally invasive two-incision approach.

Abstract: A new approach to total hip replacement, a minimally invasive two-incision technique, was developed; one incision is used for the acetabular component and the other incision is used for the femoral component. The first 100 minimally invasive two-incision THAs done at my hospital are reported. The complication rate in the first 100 cases was 1%: one proximal femoral fracture. There have been no dislocations, no failure of ingrowth, no reoperations, and no other complications. After the first 12 cases, an outpatient protocol was initiated. In the subsequent 88 patients, 75 patients (85%) chose to go home the day of surgery and 13 patients (15%) chose to go home the day after surgery. All patients were discharged to home, not to other care facilities. There were no readmissions and no complications after discharge. Radiographic analysis of the first 30 patients showed 91% of the femoral stems in neutral alignment (range, neutral -3° valgus). The abduction angle for acetabular components averaged 45° (range, 36°-54°). No component migrated or failed to show ingrowth. This two-incision minimally invasive THA technique was shown to be safe and facilitated a rapid patient recovery; however, this technique is technically challenging and only should be attempted after proper hands-on training.

Dietary fat intake and 6-year cognitive change in an older biracial community population

Abstract: Objective: To examine whether consumption of different types of fat is associated with age-related change in cognition. Methods: The authors related fat consumption to 6-year change in cognitive function among 2,560 participants of the Chicago Health and Aging Project, ages 65 and older, with no history of heart attack, stroke, or diabetes at baseline. Fat intake was measured by food frequency questionnaire. Cognitive function was measured at baseline and 3-year and 6-year follow-ups, using the average z score of four cognitive tests: the East Boston Tests of Immediate and Delayed Recall, the Mini-Mental State Examination, and the Symbol Digit Modalities Test. Results: In separate mixed models adjusted for demographic and cardiovascular risk factors and intakes of antioxidant nutrients and other dietary fats, higher intakes of saturated fat ( p for trend = 0.04) and trans-unsaturated fat ( p for trend = 0.07) were linearly associated with greater decline in cognitive score over 6 years. These associations became stronger in analyses that eliminated persons whose fat intake changed in recent years or whose baseline cognitive scores were in the lowest 15%. Inverse associations with cognitive decline were observed in these latter restricted analyses for high intake of monounsaturated fat and a high ratio of polyunsaturated to saturated fat intake. Intakes of total fat, vegetable and animal fats, and cholesterol were not associated with cognitive change. Conclusion: A diet high in saturated or trans-unsaturated fat or low in nonhydrogenated unsaturated fats may be associated with cognitive decline among older persons.