Showing papers by "Rutgers University published in 1997"

Self-rated health and mortality : a review of twenty-seven community studies

Abstract: We examine the growing number of studies of survey respondents' global self-ratings of health as predictors of mortality in longitudinal studies of representative community samples. Twenty-seven studies in U.S. and international journals show impressively consistent findings. Global self-rated health is an independent predictor of mortality in nearly all of the studies, despite the inclusion of numerous specific health status indicators and other relevant covariates known to predict mortality. We summarize and review these studies, consider various interpretations which could account for the association, and suggest several approaches to the next stage of research in this field.

M theory as a matrix model: A conjecture

Abstract: We suggest and motivate a precise equivalence between uncompactified 11-dimensional $M$ theory and the $N=\ensuremath{\infty}$ limit of the supersymmetric matrix quantum mechanics describing $D0$ branes. The evidence for the conjecture consists of several correspondences between the two theories. As a consequence of supersymmetry the simple matrix model is rich enough to describe the properties of the entire Fock space of massless well separated particles of the supergravity theory. In one particular kinematic situation the leading large distance interaction of these particles is exactly described by supergravity. The model appears to be a nonperturbative realization of the holographic principle. The membrane states required by $M$ theory are contained as excitations of the matrix model. The membrane world volume is a noncommutative geometry embedded in a noncommutative spacetime.

Maximally localized generalized Wannier functions for composite energy bands

Abstract: We discuss a method for determining the optimally localized set of generalized Wannier functions associated with a set of Bloch bands in a crystalline solid. By ''generalized Wannier functions'' we mean a set of localized orthonormal orbitals spanning the same space as the specified set of Bloch bands. Although we minimize a functional that represents the total spread Sigma(n)(r(2))(n) - (r)(n)(2) of the Wannier functions in real space, our method proceeds directly from the Bloch functions as represented on a mesh of k points, and carries out the minimization in a space of unitary matrices U-mn((k)) describing the rotation among the Bloch bands at each k point. The method is thus suitable for use in connection with conventional electronic-structure codes. The procedure also returns the total electric polarization as well as the location of each Wannier center. Sample results for Si, GaAs, molecular C2H4, and LiCl will be presented.

Spontaneous polarization and piezoelectric constants of III-V nitrides

Abstract: The spontaneous polarization, dynamical Born charges, and piezoelectric constants of the III-V nitrides AlN, GaN, and InN are studied ab initio using the Berry-phase approach to polarization in solids. The piezoelectric constants are found to be up to ten times larger than in conventional III-V and II-VI semiconductor compounds, and comparable to those of ZnO. Further properties at variance with those of conventional III-V compounds are the sign of the piezoelectric constants (positive as in II-VI compounds) and the very large spontaneous polarization.

Technical and strategic human resource management effectiveness as determinants of firm performance

Abstract: We evaluated the impact of human resource (HR) managers' capabilities on HR management effectiveness and the latter's impact on corporate financial performance. For 293 U.S. firms, effectiveness was associated with capabilities and attributes of HR staff. We also found relationships between HR management effectiveness and productivity, cash flow, and market value. Findings were consistent across market and accounting measures of performance and with corrections for biases.

Enhanced Accumulation of Pb in Indian Mustard by Soil-Applied Chelating Agents

Abstract: Phytoremediation is emerging as a potential cost-effective solution for the remediation of contaminated soils. Because contaminants such as lead (Pb) have limited bioavailability in the soil, a means of solubilizing the Pb in the soil and facilitating its transport to the shoots of plants is vital to the success of phytoremediation. Indian mustard (Brassica juncea) was used to demonstrate the capability of plants to accumulate high tissue concentrations of Pb when grown in Pb-contaminated soil. Concentrations of 1.5% Pb in the shoots of B. juncea were obtained from soils containing 600 mg of Pb/kg amended with synthetic chelates such as EDTA. The accumulation of Pb in the tissue corresponded to the concentration of Pb in the soil and the concentration of EDTA added to the soil. The accumulation of Cd, Cu, Ni, and Zn from contaminated soil amended with EDTA and other synthetic chelators was also demonstrated. The research indicates that the accumulation of metal in the shoots of B. juncea can be enhanced t...

Restricted structural gene polymorphism in the Mycobacterium tuberculosis complex indicates evolutionarily recent global dissemination

Abstract: One-third of humans are infected with Mycobacterium tuberculosis, the causative agent of tuberculosis. Sequence analysis of two megabases in 26 structural genes or loci in strains recovered globally discovered a striking reduction of silent nucleotide substitutions compared with other human bacterial pathogens. The lack of neutral mutations in structural genes indicates that M. tuberculosis is evolutionarily young and has recently spread globally. Species diversity is largely caused by rapidly evolving insertion sequences, which means that mobile element movement is a fundamental process generating genomic variation in this pathogen. Three genetic groups of M. tuberculosis were identified based on two polymorphisms that occur at high frequency in the genes encoding catalase-peroxidase and the A subunit of gyrase. Group 1 organisms are evolutionarily old and allied with M. bovis, the cause of bovine tuberculosis. A subset of several distinct insertion sequence IS6110 subtypes of this genetic group have IS6110 integrated at the identical chromosomal insertion site, located between dnaA and dnaN in the region containing the origin of replication. Remarkably, study of ≈6,000 isolates from patients in Houston and the New York City area discovered that 47 of 48 relatively large case clusters were caused by genotypic group 1 and 2 but not group 3 organisms. The observation that the newly emergent group 3 organisms are associated with sporadic rather than clustered cases suggests that the pathogen is evolving toward a state of reduced transmissability or virulence.

The AETG system: an approach to testing based on combinatorial design

Abstract: This paper describes a new approach to testing that uses combinatorial designs to generate tests that cover the pairwise, triple, or n-way combinations of a system's test parameters. These are the parameters that determine the system's test scenarios. Examples are system configuration parameters, user inputs and other external events. We implemented this new method in the AETG system. The AETG system uses new combinatorial algorithms to generate test sets that cover all valid n-way parameter combinations. The size of an AETG test set grows logarithmically in the number of test parameters. This allows testers to define test models with dozens of parameters. The AETG system is used in a variety of applications for unit, system, and interoperability testing. It has generated both high-level test plans and detailed test cases. In several applications, it greatly reduced the cost of test plan development.

AICA riboside increases AMP-activated protein kinase, fatty acid oxidation, and glucose uptake in rat muscle

Abstract: 5-Aminoimidazole-4-carboxamide ribonucleoside (AICAR) has previously been reported to be taken up into cells and phosphorylated to form ZMP, an analog of 5′-AMP This study was designed to determin

Topics in classical automorphic forms

Abstract: Introduction The classical modular forms Automorphic forms in general The Eisenstein and the Poincare series Kloosterman sums Bounds for the Fourier coefficients of cusp forms Hecke operators Automorphic $L$-functions Cusp forms associated with elliptic curves Spherical functions Theta functions Representations by quadratic forms Automorphic forms associated with number fields Convolution $L$-functions Bibliography Index.

Role of goal orientation, ability, need for achievement, and locus of control in the self-efficacy and goal--setting process.

Abstract: This study integrates ability, goal setting, self-efficacy, and multiple personality traits into a common framework that explains and predicts individual performance. A mediational model was tested using LISREL 8. Ability, learning goal orientation, and locus of control were positively related to self-efficacy, whereas performance goal orientation was negatively related to self-efficacy on an academic task. Self-efficacy and need for achievement were positively related to goal level, which was positively related to performance in combination with ability and self-efficacy. In addition to showing that personality traits can influence the motivational process at various stages, the results highlight the unique contributions of self-efficacy and goal level to the motivational process after the effects of ability and other individual differences have been identified.

Antioxidant activities of caffeic acid and its related hydroxycinnamic acid compounds

Abstract: Hydroxycinnamic acid compounds are an important source of antioxidants due to their ubiquitous occurrence in the plant kingdom and their characteristic activities. In this study, we compared the antioxidative and free radical scavenging activities of caffeic acid (CA), caffeic acid phenethyl ester (CAPE), ferulic acid (FA), ferulic acid phenethyl ester (FAPE), rosmarinic acid (RA), and chlorogenic acid (CHA) with those of α-tocopherol and BHT. In the Rancimat test, the addition of test compounds in lard significantly extended the induction time of lipid oxidation, and the activities in decreasing order were CA ∼ α-tocopherol > CAPE ∼ RA > CHA ≫ BHT > FA ∼ FAPE. When the lipid substrate was changed to corn oil, the effectiveness of antioxidants on the induction time was obviously decreased, and the potency order of antioxidants was changed to RA > CA ∼ CAPE ∼ CHA > α-tocopherol > BHT; FA and FAPE had no significant antioxidative effect in the corn oil system. The 2,2-diphenyl-1-picrylhydrazyl radical (DPPH...

A review of innovation research in economics, sociology and technology management

Abstract: In this paper we review the extant innovation research from three fields—economics, organizational sociology and technology management—in order to find points at which the fields' approaches and assumptions overlap. By comparing research methods and approaches along three dimensions, stage of adoption, level of analysis, and type of innovation, we found, firstly, that studies from the three fields can be re-mapped into five more specific groups. We then illustrate how research from different groups can be cross-fertilized to help management of innovation in organizations. The paper suggests that knowing the ways in which different groups of studies differ from each other may lead to a more accurate understanding of the relative value of innovation research from each group, for both theorists and managers.

Trichomonas vaginalis associated with low birth weight and preterm delivery. The Vaginal Infections and Prematurity Study Group.

Abstract: Background:Several studies have suggested that pregnant women infected withTrichomonas vaginalismay be at increased risk of an adverse outcome.Goal:To evaluate prospectively the association betweenT. vaginalisand risk of adverse pregnancy outcome in a large cohort of ethnically diverse women.Study D

Robust analysis of feature spaces: color image segmentation

Abstract: A general technique for the recovery of significant image features is presented. The technique is based on the mean shift algorithm, a simple nonparametric procedure for estimating density gradients. Drawbacks of the current methods (including robust clustering) are avoided. Feature space of any nature can be processed, and as an example, color image segmentation is discussed. The segmentation is completely autonomous, only its class is chosen by the user. Thus, the same program can produce a high quality edge image, or provide, by extracting all the significant colors, a preprocessor for content-based query systems. A 512/spl times/512 color image is analyzed in less than 10 seconds on a standard workstation. Gray level images are handled as color images having only the lightness coordinate.

HR as a Source of Shareholder Value: Research and Recommendations

Abstract: The role of the Human Resource Management (HRM) function in many organizations is at a crossroads. On one hand, the HRM function is in crisis, increasingly under fire to justify itself (Schuler, 1990; Stewart, 1996) and confronted with the very real prospect that a significant portion of its traditional responsibilities will be outsourced (Corporate Leadership Council, 1995). On the other hand, organizations have an unprecedented opportunity to refocus their HRM systems as strategic assets. Indeed, the same competitive pressures that provide an incentive for firms to outsource costly HRM transactions have dramatically increased the strategic value of a skilled, motivated, adaptable workforce, and the HRM system that supports and develops it .Transforming this crisis into an opportunity, however, requires a new organizational perspective on the HRM system, one that is also a perspective shared by the CEO and the chief HR officer (CHRO). At its core, this strategic perspective requires that the CHRO be focused on identifying and solving the human capital elements of important business problems (e.g., those problems likely to impede growth, lower profitability, and diminish shareholder value). The tangible evidence of this focus is an internally coherent, externally aligned, and effectively implemented HRM system.

Airborne signalling by methyl salicylate in plant pathogen resistance

Abstract: Methyl salicylate, a volatile liquid, also known as oil of winter-green, is made by a number of plants1–9. Here we show that methyl salicylate is a major volatile compound produced by tobacco plants inoculated with tobacco mosaic virus. Methyl salicylate is synthesized from salicylic acid, a non-volatile chemical signal required for the establishment of acquired resistance10 and local and systemic induction of antimicrobial pathogenesis-related proteins11. Methyl salicylate acts by being converted back to salicyclic acid. We conclude that methyl salicylate may function as an airborne signal which acitvates disease resistance and the expression of defence-related genes in neighbouring plants and in the healthy tissues of the infected plant.

Prospective study of blunt aortic injury: Multicenter trial of the American Association for the Surgery of Trauma

Abstract: Background: Blunt aortic injury is a major cause of death from blunt trauma. Evolution of diagnostic techniques and methods of operative repair have altered the management and posed new questions in recent years. Methods: This study was a prospectively conducted multicenter trial involving 50 trauma centers in North America under the direction of the Multi-institutional Trial Committee of the American Association for the Surgery of Trauma. Results: There were 274 blunt aortic injury cases studied over 2.5 years, of which 81% were caused by automobile crashes. Chest computed tomography and transesophageal echocardiography were applied in 88 and 30 cases, respectively, and were 75 and 80% diagnostic, respectively. Two hundred seven stable patients underwent planned thoracotomy and repair. Clamp and sew technique was used in 73 (35%) and bypass techniques in 134 (65%). Overall mortality was 31%, with 63% of deaths being attributable to aortic rupture; mortality was not affected by method of repair. Paraplegia occurred postoperatively in 8.7%. Logistic regression analysis demonstrated clamp and sew (p = 0.002) and aortic cross clamp time of 30 minutes (p = 0.01) to be associated with development of postoperative paraplegia. Conclusions: Rupture after hospital admission remains a major problem. Although newer diagnostic techniques are being applied, at this time aortography remains the diagnostic standard. Aortic cross clamp time beyond 30 minutes was associated with paraplegia; bypass techniques, which provide distal aortic perfusion, produced significantly lower paraplegia rates than the clamp and sew approach.

Lectures on supersymmetric gauge theories and electric-magnetic duality

Abstract: We review some of the recent work on the dynamics of four dimensional, supersymmetric gauge theories. The kinematics are largely determined by holomorphy and the dynamics are governed by duality. The results shed light on the phases of gauge theories. Some results and interpretations which have not been published before are also included.

Biodiversity regulates ecosystem predictability

Abstract: Links between biodiversity and ecosystem function provide compelling reasons for conserving maximal numbers of species in ecosystems1,2,3,4,5,6. Here we describe a previously unrecognized effect of biodiversity on ecosystem predictability, where predictability is inversely related to temporal and spatial variation in ecosystem properties. By manipulating biodiversity in aquatic microbial communities, we show that one process, ecosystem respiration, becomes more predictable as biodiversity increases. Analysis of similar patterns extracted from other studies2,3,6 indicates that biodiversity also enhances predictability in terrestrial ecosystems. Biodiversity can also affect average levels of ecosystem performance, but the extent to which different species make unique or redundant contributions to ecosystem processes remains controversial3,7,8,9,10. Nonlinear effects of biodiversity on the decomposition of particulate organic matter and resistance of communities to invasion indicate that different species have redundant functions in our system. The consequences of biodiversity are also not restricted to early successional situations as described in previous studies1,2,3,4,6, because strong effects persist even after ecosystems develop for periods corresponding to 40–80 generations of dominant organisms.

Synthetic Water-Oxidation Catalysts for Artificial Photosynthetic Water Oxidation.

Abstract: This review focuses primarily on homogeneous catalysts for the oxidation of water, but does include selected heterogeneous systems. It does not attempt to summarize all chemistry related to systems that are capable of oxidizing water. In particular, heterogeneous catalysts that have no direct relevance to understanding the WOC [water-oxidizing complex] are not discussed in detail. Neither are nonbiomimetic systems for artificial photosynthesis or water-splitting in its elements discussed. However, a list of some of the recent references in these areas can be found in section X (Nonbiomimetic Water Oxidation Catalysts). The authors will first give a brief summary of the current view of the photosynthetic WOC and its functionality, followed by analysis of the thermodynamic and kinetic constraints for water-oxidation that have to be overcome by any catalyst. Since manganese is the metal that performs this reaction in the WOC, manganese catalysts will be discussed first, followed by other transition metals, particularly ruthenium. In the final section the authors summarize the principles of reactivity learned from theory and existing models that will guide one toward synthesis of better catalysts in the future. This review does not attempt to summarize manganese chemistry relevant to nonfunctional (structural) models of the WOC, whichmore » has been reviewed recently. Water-oxidation catalysts are intrinsically important in their own right, independent of possible biological relevance. They have direct applications as catalysts in artificial photosynthetic systems for the splitting of water that could be used in future fuel cells for the generation of electricity. 133 refs.« less

DNA sequence evidence for the segmental allotetraploid origin of maize

Abstract: It has long been suspected that maize is the product of an historical tetraploid event. Several observations support this possibility, including the fact that the maize genome contains duplicated chromosomal segments with colinear gene arrangements. Some of the genes from these duplicated segments have been sequenced. In this study, we examine the pattern of sequence divergence among 14 pairs of duplicated genes. We compare the pattern of divergence to patterns predicted by four models of the evolution of the maize genome—autotetraploidy, genomic allotetraploidy, segmental allotetraploidy, and multiple segmental duplications. Our analyses indicate that coalescent times for duplicated sequences fall into two distinct groups, corresponding to roughly 20.5 and 11.4 million years. This observation strongly discounts the possibility that the maize genome is the product of a genomic allotetraploid event, and it is also difficult to reconcile with either autotetraploidy or multiple independent segmental duplications. However, the presence of two (and only two) coalescent times is predicted by the segmental allotetraploid model. If the maize genome is the product of a segmental allotetraploid event, as these data suggest, then its two diploid progenitors diverged roughly 20.5 million years ago (Mya), and the allotetraploid event probably occurred approximately 11.4 Mya. Comparison of maize and sorghum sequences suggests that one of the two ancestral diploids shares a more recent common ancestor with sorghum than it does with the other ancestral diploid.

Prevention of Heart Failure by Antihypertensive Drug Treatment in Older Persons With Isolated Systolic Hypertension

Abstract: Context. —Heart failure is often preceded by isolated systolic hypertension, but the effectiveness of antihypertensive treatment in preventing heart failure is not known. Objective. —To assess the effect of diuretic-based antihypertensive stepped-care treatment on the occurrence of heart failure in older persons with isolated systolic hypertension. Design. —Analysis of data from a multicenter, randomized, double-blind, placebo-controlled clinical trial. Participants. —A total of 4736 persons aged 60 years and older with systolic blood pressure between 160 and 219 mm Hg and diastolic blood pressure below 90 mm Hg who participated in the Systolic Hypertension in the Elderly Program (SHEP). Intervention. —Stepped-care antihypertensive drug therapy, in which the step 1 drug is chlorthalidone (12.5-25 mg) or matching placebo, and the step 2 drug is atenolol (25-50 mg) or matching placebo. Main Outcome Measures. —Fatal and nonfatal heart failure. Results. —During an average of 4.5 years of follow-up, fatal or nonfatal heart failure occurred in 55 of 2365 patients randomized to active therapy and 105 of the 2371 patients randomized to placebo (relative risk [RR], 0.51; 95% confidence interval [CI], 0.37-0.71;P Conclusion. —In older persons with isolated systolic hypertension, stepped-care treatment based on low-dose chlorthalidone exerted a strong protective effect in preventing heart failure. Among patients with prior MI, an 80% risk reduction was observed.

Data on air: organization and access

Abstract: Organizing massive amount of data on wireless communication networks in order to provide fast and low power access to users equipped with palmtops, is a new challenge to the data management and telecommunication communities. Solutions must take under consideration the physical restrictions of low network bandwidth and limited battery life of palmtops. This paper proposes algorithms for multiplexing clustering and nonclustering indexes along with data on wireless networks. The power consumption and the latency for obtaining the required data are considered as the two basic performance criteria for all algorithms. First, this paper describes two algorithms namely, (1, m) indexing and Distributed Indexing, for multiplexing data and its clustering index. Second, an algorithm called Nonclustered Indexing is described for allocating static data and its corresponding nonclustered index. Then, the Nonclustered indexing algorithm is generalized to the case of multiple indexes. Finally, the proposed algorithms are analytically demonstrated to lead to significant improvement of battery life while retaining a low latency.