Rutgers University

About: Rutgers University is a education organization based out in New Brunswick, New Jersey, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 68736 authors who have published 159418 publications receiving 6713860 citations. The organization is also known as: Rutgers, The State University of New Jersey & Rutgers.

A general result on the stabilization of linear systems using bounded controls

Abstract: We present two constructions of controllers that globally stabilize linear systems subject to control saturation. We allow essentially arbitrary saturation functions. The only conditions imposed on the system are the obvious necessary ones, namely that no eigenvalues of the uncontrolled system have positive real part and that the standard stabilizability rank condition hold. One of the constructions is in terms of a "neural-network type" one-hidden layer architecture, while the other one is in terms of cascades of linear maps and saturations. >

Organizational knowledge, learning and memory: three concepts in search of a theory

Abstract: There is much interest in organizational knowledge following the recognition of its strategic place in inter‐firm competition, but there is no adequate theory of such knowledge, or of its acquisition, storage and application. Penrose’s (1959) theory of the growth of the firm, Nelson and Winter’s (1982) evolutionary economics, and the gestalt notions of discontinuous perceptual change taken from Lewin (1935), still define the cutting edge of the learning and knowledge‐based approaches to the firm. Compared with these field‐shaping works, the recent literature on organizational knowledge, learning and memory seems inconclusive. Takes a new start from the Jamesian distinction between knowing what and knowing how, and the Durkheimian distinction between individual and social forms of knowledge. The resulting pluralistic organizational epistemology implies a dynamic theory of the firm as a dialectical system of knowledge processes.

Supermassive Black Holes in Galactic Nuclei: Past, Present and Future Research

Abstract: This review discusses the current status of supermassive black hole research, as seen from a purely observational standpoint Since the early ‘90s, rapid technological advances, most notably the launch of the Hubble Space Telescope, the commissioning of the VLBA and improvements in near-infrared speckle imaging techniques, have not only given us incontrovertible proof of the existence of supermassive black holes, but have unveiled fundamental connections between the mass of the central singularity and the global properties of the host galaxy It is thanks to these observations that we are now, for the first time, in a position to understand the origin, evolution and cosmic relevance of these fascinating objects

Dehydrogenation and related reactions catalyzed by iridium pincer complexes

Abstract: s of Papers, 221st ACS National Meeting, San Diego, CA, April 1-5, 2001; American Chemical Society:Washington, DC, 2001; INOR287. (b) Dijkstra, H. P.; Slagt, M. Q.; McDonald, A.; Kruithof, C. A.; Kreiter, R.; Mills, A. M.; Lutz, M.; Spek, A. L.; Klopper, W.; van Klink, G. P. M.; van Koten, G. Eur. J. Inorg. Chem. 2003, 830. (c) Mehendale, N. C.; Bezemer, C.; van Walree, C. A.; Klein Gebbink, R. J. M.; van Koten, G. J. Mol. Catal. A 2006, 257, 167. (d)Mehendale, N. C.; Sietsma, J. R. A.; de Jong, K. P.; vanWalree, C. A.; Gebbink, R. J. M. K.; van Koten, G. Adv. Synth. Catal. 2007, 349, 2619. (e) Mehendale, N. C.; Lutz, M.; Spek, A. L.; Klein Gebbink, R. J. M.; van Koten, G. J. Organomet. Chem. 2008, 693, 2971. (f)McDonald, A. R.; Dijkstra, H. P.; Suijkerbuijk, B.M. J. M.; van Klink, G. P. M.; van Koten, G.Organometallics 2009, 28, 4689. (g) McDonald, A. R.; Franssen, N.; van Klink, G. P. M.; van Koten, G. J. Organomet. Chem. 2009, 694, 2153. (h) O’Leary, P.; vanWalree, C. A.; Mehendale, N. C.; Sumerel, J.; Morse, D. E.; Kaska, W. C.; van Koten, G.; Klein Gebbink, R. J. M. Dalton Trans. 2009, 4289. (164) Gimenez, R.; Swager, T. M. J. Mol. Catal. A 2001, 166, 265. (165) Poyatos, M.; Marquez, F.; Peris, E.; Claver, C.; Fernandez, E. New J. Chem. 2003, 27, 425. (166) Yu, K.; Sommer, W.; Weck, M.; Jones, C. W. J. Catal. 2004, 226, 101. (167) Sommer,W. J.; Yu, K.; Sears, J. S.; Ji, Y.; Zheng, X.; Davis, R. J.; Sherrill, C. D.; Jones, C. W.; Weck, M. Organometallics 2005, 24, 4351. (168) Brookhart, M.; Huang, Z.; MacArthur, A. H.; Carson, E. C.; Goldman, A.; Scott, S. L.; Vicente, B. C. Abstracts of Papers, 239th ACS National Meeting, San Francisco, CA, March 21-25, 2010; American Chemical Society: Washington, DC, 2010; CATL-79. (169) del Pozo, C.; Corma, A.; Iglesias, M.; Sanchez, F. Organometallics 2010, 29, 4491.

Fringe is a glycosyltransferase that modifies Notch

Abstract: Notch receptors function in highly conserved intercellular signalling pathways that direct cell-fate decisions, proliferation and apoptosis in metazoans. Fringe proteins can positively and negatively modulate the ability of Notch ligands to activate the Notch receptor. Here we establish the biochemical mechanism of Fringe action. Drosophila and mammalian Fringe proteins possess a fucose-specific β1,3 N-acetylglucosaminyltransferase activity that initiates elongation of O-linked fucose residues attached to epidermal growth factor-like sequence repeats of Notch. We obtained biological evidence that Fringe-dependent elongation of O-linked fucose on Notch modulates Notch signalling by using co-culture assays in mammalian cells and by expression of an enzymatically inactive Fringe mutant in Drosophila . The post-translational modification of Notch by Fringe represents a striking example of modulation of a signalling event by differential receptor glycosylation and identifies a mechanism that is likely to be relevant to other signalling pathways.