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Institution

RWTH Aachen University

EducationAachen, Nordrhein-Westfalen, Germany
About: RWTH Aachen University is a education organization based out in Aachen, Nordrhein-Westfalen, Germany. It is known for research contribution in the topics: Population & Catalysis. The organization has 49754 authors who have published 96212 publications receiving 2581377 citations. The organization is also known as: Rheinisch-Westfälische Technische Hochschule Aachen & Technical University of Aachen.


Papers
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Journal ArticleDOI
TL;DR: Systemic reaction characterized by fever, leukocytosis, increase in erythrocyte sedimentation rate, increases in LeucocyTosis secretion of ACTH and glucocorticoids, and by dramatic changes in the concentration of some plasma ,l' proteins.
Abstract: systemic reaction characterized by fever, leukocytosis, increase in erythrocyte sedimentation rate, increases in Leucocytosis secretion of ACTH and glucocorticoids, activation of Complement activat complement and clotting cascades, decreases in serum levels of iron and zinc, a negative nitrogen balance, and by dramatic changes in the concentration of some plasma ,l' proteins. These proteins are named acute phase proteins. i

2,680 citations

Journal ArticleDOI
Frank Arute1, Kunal Arya1, Ryan Babbush1, Dave Bacon1, Joseph C. Bardin2, Joseph C. Bardin1, Rami Barends1, Rupak Biswas3, Sergio Boixo1, Fernando G. S. L. Brandão4, Fernando G. S. L. Brandão1, David A. Buell1, B. Burkett1, Yu Chen1, Zijun Chen1, Ben Chiaro5, Roberto Collins1, William Courtney1, Andrew Dunsworth1, Edward Farhi1, Brooks Foxen1, Brooks Foxen5, Austin G. Fowler1, Craig Gidney1, Marissa Giustina1, R. Graff1, Keith Guerin1, Steve Habegger1, Matthew P. Harrigan1, Michael J. Hartmann6, Michael J. Hartmann1, Alan Ho1, Markus R. Hoffmann1, Trent Huang1, Travis S. Humble7, Sergei V. Isakov1, Evan Jeffrey1, Zhang Jiang1, Dvir Kafri1, Kostyantyn Kechedzhi1, Julian Kelly1, Paul V. Klimov1, Sergey Knysh1, Alexander N. Korotkov8, Alexander N. Korotkov1, Fedor Kostritsa1, David Landhuis1, Mike Lindmark1, E. Lucero1, Dmitry I. Lyakh7, Salvatore Mandrà3, Jarrod R. McClean1, Matt McEwen5, Anthony Megrant1, Xiao Mi1, Kristel Michielsen9, Kristel Michielsen10, Masoud Mohseni1, Josh Mutus1, Ofer Naaman1, Matthew Neeley1, Charles Neill1, Murphy Yuezhen Niu1, Eric Ostby1, Andre Petukhov1, John Platt1, Chris Quintana1, Eleanor Rieffel3, Pedram Roushan1, Nicholas C. Rubin1, Daniel Sank1, Kevin J. Satzinger1, Vadim Smelyanskiy1, Kevin J. Sung11, Kevin J. Sung1, Matthew D. Trevithick1, Amit Vainsencher1, Benjamin Villalonga12, Benjamin Villalonga1, Theodore White1, Z. Jamie Yao1, Ping Yeh1, Adam Zalcman1, Hartmut Neven1, John M. Martinis1, John M. Martinis5 
24 Oct 2019-Nature
TL;DR: Quantum supremacy is demonstrated using a programmable superconducting processor known as Sycamore, taking approximately 200 seconds to sample one instance of a quantum circuit a million times, which would take a state-of-the-art supercomputer around ten thousand years to compute.
Abstract: The promise of quantum computers is that certain computational tasks might be executed exponentially faster on a quantum processor than on a classical processor1. A fundamental challenge is to build a high-fidelity processor capable of running quantum algorithms in an exponentially large computational space. Here we report the use of a processor with programmable superconducting qubits2-7 to create quantum states on 53 qubits, corresponding to a computational state-space of dimension 253 (about 1016). Measurements from repeated experiments sample the resulting probability distribution, which we verify using classical simulations. Our Sycamore processor takes about 200 seconds to sample one instance of a quantum circuit a million times-our benchmarks currently indicate that the equivalent task for a state-of-the-art classical supercomputer would take approximately 10,000 years. This dramatic increase in speed compared to all known classical algorithms is an experimental realization of quantum supremacy8-14 for this specific computational task, heralding a much-anticipated computing paradigm.

2,527 citations

Book
01 Jan 1998
TL;DR: This chapter discusses abstract reduction systems, universal algebra, and Grobner bases and Buchberger's algorithm, and a bluffer's guide to ML Bibliography Index.
Abstract: Preface 1. Motivating examples 2. Abstract reduction systems 3. Universal algebra 4. Equational problems 5. Termination 6. Confluence 7. Completion 8. Grobner bases and Buchberger's algorithm 9. Combination problems 10. Equational unification 11. Extensions Appendix 1. Ordered sets Appendix 2. A bluffer's guide to ML Bibliography Index.

2,515 citations

Journal ArticleDOI
Andre Franke1, Dermot P.B. McGovern2, Jeffrey C. Barrett3, Kai Wang4, Graham L. Radford-Smith5, Tariq Ahmad6, Charlie W. Lees7, Tobias Balschun1, James Lee8, Rebecca L. Roberts9, Carl A. Anderson3, Joshua C. Bis10, Suzanne Bumpstead3, David Ellinghaus1, Eleonora M. Festen11, Michel Georges12, Todd Green13, Talin Haritunians2, Luke Jostins3, Anna Latiano14, Christopher G. Mathew15, Grant W. Montgomery5, Natalie J. Prescott15, Soumya Raychaudhuri13, Jerome I. Rotter2, Philip Schumm16, Yashoda Sharma17, Lisa A. Simms5, Kent D. Taylor2, David C. Whiteman5, Cisca Wijmenga11, Robert N. Baldassano4, Murray L. Barclay9, Theodore M. Bayless18, Stephan Brand19, Carsten Büning20, Albert Cohen21, Jean Frederick Colombel22, Mario Cottone, Laura Stronati, Ted Denson23, Martine De Vos24, Renata D'Incà, Marla Dubinsky2, Cathryn Edwards25, Timothy H. Florin26, Denis Franchimont27, Richard B. Gearry9, Jürgen Glas19, Jürgen Glas28, Jürgen Glas22, André Van Gossum27, Stephen L. Guthery29, Jonas Halfvarson30, Hein W. Verspaget31, Jean-Pierre Hugot32, Amir Karban33, Debby Laukens24, Ian C. Lawrance34, Marc Lémann32, Arie Levine35, Cécile Libioulle12, Edouard Louis12, Craig Mowat36, William G. Newman37, Julián Panés, Anne M. Phillips36, Deborah D. Proctor17, Miguel Regueiro38, Richard K Russell39, Paul Rutgeerts40, Jeremy D. Sanderson41, Miquel Sans, Frank Seibold42, A. Hillary Steinhart43, Pieter C. F. Stokkers44, Leif Törkvist45, Gerd A. Kullak-Ublick46, David C. Wilson7, Thomas D. Walters43, Stephan R. Targan2, Steven R. Brant18, John D. Rioux47, Mauro D'Amato45, Rinse K. Weersma11, Subra Kugathasan48, Anne M. Griffiths43, John C. Mansfield49, Severine Vermeire40, Richard H. Duerr38, Mark S. Silverberg43, Jack Satsangi7, Stefan Schreiber1, Judy H. Cho17, Vito Annese14, Hakon Hakonarson4, Mark J. Daly13, Miles Parkes8 
TL;DR: A meta-analysis of six Crohn's disease genome-wide association studies and a series of in silico analyses highlighted particular genes within these loci implicated functionally interesting candidate genes including SMAD3, ERAP2, IL10, IL2RA, TYK2, FUT2, DNMT3A, DENND1B, BACH2 and TAGAP.
Abstract: We undertook a meta-analysis of six Crohn's disease genome-wide association studies (GWAS) comprising 6,333 affected individuals (cases) and 15,056 controls and followed up the top association signals in 15,694 cases, 14,026 controls and 414 parent-offspring trios. We identified 30 new susceptibility loci meeting genome-wide significance (P < 5 × 10⁻⁸). A series of in silico analyses highlighted particular genes within these loci and, together with manual curation, implicated functionally interesting candidate genes including SMAD3, ERAP2, IL10, IL2RA, TYK2, FUT2, DNMT3A, DENND1B, BACH2 and TAGAP. Combined with previously confirmed loci, these results identify 71 distinct loci with genome-wide significant evidence for association with Crohn's disease.

2,482 citations

Journal ArticleDOI
TL;DR: The inversion of the classical reactivity (Umpolung) opens up new synthetic pathways in biochemical processes as nucleophilic acylations and in nature, the coenzyme thiamine (vitamin B1), a natural thiazolium salt, utilizes a catalytic variant of this concept in biochemical process as nucleophile acylation.
Abstract: In the investigation of efficient chemical transformations, the carbon-carbon bond-forming reactions play an outstanding role. In this context, organocatalytic processes have achieved considerable attention. 1 Beside their facile reaction course, selectivity, and environmental friendliness, new synthetic strategies are made possible. Particularly, the inversion of the classical reactivity (Umpolung) opens up new synthetic pathways. 2 In nature, the coenzyme thiamine (vitamin B1), a natural thiazolium salt, utilizes a catalytic variant of this concept in biochemical processes as nucleophilic acylations. 3 The catalytically active species is a nucleophilic carbene. 4

2,351 citations


Authors

Showing all 50249 results

NameH-indexPapersCitations
Jing Wang1844046202769
H. S. Chen1792401178529
Robin M. Murray1711539116362
Bradley Cox1692150156200
Michael Kramer1671713127224
Marc Weber1672716153502
Hannes Jung1592069125069
Wolfgang Wagner1562342123391
Barry J. Maron15579291595
Mercouri G. Kanatzidis1521854113022
Thomas Hebbeker1481984114004
Manel Esteller14671396429
Daniel Bloch1451819119556
Martin Erdmann1441562100470
Christopher George Tully1421843111669
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023246
2022937
20216,328
20206,114
20195,779
20185,514