Institution
Ryerson University
Education•Toronto, Ontario, Canada•
About: Ryerson University is a education organization based out in Toronto, Ontario, Canada. It is known for research contribution in the topics: Population & Poison control. The organization has 7671 authors who have published 20164 publications receiving 394976 citations. The organization is also known as: Ryerson Polytechnical Institute & Ryerson Institute of Technology.
Papers published on a yearly basis
Papers
More filters
••
TL;DR: The authors conclude that the irradiation of GNP at lower photon energies will be more efficient for cell killing, consistent with published studies.
Abstract: Purpose: The aim of this study is to understand the characteristics of secondary electrons generated from the interaction of gold nanoparticles (GNPs) with x-rays as a function of nanoparticle size and beam energy and thereby further the understanding of GNP-enhanced radiotherapy. Methods: The effective range, deflection angle, dose deposition, energy, and interaction processes of electrons produced from the interaction of x-rays with a GNP were calculated by Monte Carlo simulations. The GEANT4 code was used to simulate and track electrons generated from a 2, 50, and 100 nm diameter GNP when it is irradiated with a 50 kVp, 250 kVp, cobalt-60, and 6 MV photon beam in water. Results: When a GNP was present, depending on the beam energies used, secondary electron production was increased by 10- to 2000-fold compared to an absence of a GNP. Low-energy photon beams were much more efficient at interacting with the GNP by two to three orders of magnitude compared to MV energies and increased the deflection angle. GNPs with larger diameters also contributed more dose. The majority of the energy deposition was outside the GNP, rather than self-absorbed by the nanoparticle. The mean effective range of electron tracks for the beams tested rangedmore » from approximately 3 {mu}m to 1 mm. Conclusions: These simulated results yield important insights concerning the spatial distributions and elevated dose in GNP-enhanced radiotherapy. The authors conclude that the irradiation of GNP at lower photon energies will be more efficient for cell killing. This conclusion is consistent with published studies.« less
226 citations
••
TL;DR: These represent likely extra- and intracellular antioxidant activities of flax-derived lignans at concentrations potentially achievable in vivo, andBenzylic hydrogen abstraction and potential resonance stabilization of phenoxyl radicals in an aqueous environment likely contributed to the antioxidant activity of the mammalian lignan.
225 citations
••
TL;DR: This work explores the symbiotic role of mathematical models and experimental assays in improving the quantitative understanding of influenza infection dynamics, and discusses the challenges in developing better, more comprehensive models for the course of influenza infections within a host or cell culture.
Abstract: Most mathematical models used to study the dynamics of influenza A have thus far focused on the between-host population level, with the aim to inform public health decisions regarding issues such as drug and social distancing intervention strategies, antiviral stockpiling or vaccine distribution. Here, we investigate mathematical modeling of influenza infection spread at a different scale; namely that occurring within an individual host or a cell culture. We review the models that have been developed in the last decades and discuss their contributions to our understanding of the dynamics of influenza infections. We review kinetic parameters (e.g., viral clearance rate, lifespan of infected cells) and values obtained through fitting mathematical models, and contrast them with values obtained directly from experiments. We explore the symbiotic role of mathematical models and experimental assays in improving our quantitative understanding of influenza infection dynamics. We also discuss the challenges in developing better, more comprehensive models for the course of influenza infections within a host or cell culture. Finally, we explain the contributions of such modeling efforts to important public health issues, and suggest future modeling studies that can help to address additional questions relevant to public health.
224 citations
••
TL;DR: The current body of research that has extended the Salameh and Jaber (2000) EOQ model for imperfect items, and the impact of human error on production and inventory systems is summarized.
223 citations
••
TL;DR: Evidence is provided that, as a group, anxiety and related conditions affect a significant proportion of postpartum women, and are more prevalent than is post partum depression.
223 citations
Authors
Showing all 7846 results
Name | H-index | Papers | Citations |
---|---|---|---|
Eleftherios P. Diamandis | 110 | 1064 | 52654 |
Michael D. Taylor | 97 | 505 | 42789 |
Peter Nijkamp | 97 | 2407 | 50826 |
Anthony B. Miller | 93 | 416 | 36777 |
Muhammad Shahbaz | 92 | 1001 | 34170 |
Rakesh Kumar | 91 | 1959 | 39017 |
Marc A. Rosen | 85 | 770 | 30666 |
Bjorn Ottersten | 81 | 1058 | 28359 |
Barry Wellman | 77 | 219 | 34234 |
Bin Wu | 73 | 464 | 24877 |
Xinbin Feng | 72 | 413 | 19193 |
Roy Freeman | 69 | 254 | 22707 |
Xiaokang Yang | 68 | 518 | 17663 |
Amir H. Gandomi | 67 | 375 | 22192 |
Konstantinos N. Plataniotis | 63 | 595 | 16695 |