Institution
Saint Francis University
Education•Loretto, Pennsylvania, United States•
About: Saint Francis University is a education organization based out in Loretto, Pennsylvania, United States. It is known for research contribution in the topics: Population & Osteoblast. The organization has 1694 authors who have published 2038 publications receiving 87149 citations.
Topics: Population, Osteoblast, Growth factor, Bone cell, Health care
Papers published on a yearly basis
Papers
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TL;DR: Outcomes in patients undergoing TAVR with the self-expanding CoreValve prosthesis are compared by direct aortic access vs iliofemoral access, which allows effective delivery of the valve but incurs an increased risk of death and adverse events, potentially the result of procedural differences.
17 citations
TL;DR: The results help elucidate the impact of AMD onδ(2)HH2O and δ(18)OH2O compositions for karst waters and demonstrate the utility for impact assessments and remediation planning in these unique systems.
17 citations
TL;DR: Advances in health information technology provide significant opportunities for improvements in surgical patient safety and the adoption and use of electronic health records can enhance communication along the surgical spectrum of care.
17 citations
TL;DR: The results suggest that this compound alleviates infantile anxiety-like behavior with great specificity in rats bred for high anxiety/depressive phenotypes by selectively targeting 5-HT1A receptors, possibly by both pre- and post-synaptic mechanisms.
Abstract: To address the development of early anxiety disorders across the lifespan, the High USV line of rats was bred based on rates of infant ultrasonic vocalization in the 40–50 kHz range of predominant frequencies (USV) to maternal separation at postnatal day (P) 10. In this study, rates of USV in High line infants (pups: Postnatal Day 11 ± 1) were compared to those of randomly-bred controls in response to EPIX compound PRX-00023, a unique serotonin (5-HT) agonist, acting exclusively at the 5-HT1A receptor, or buspirone, a nonspecific 5HT1A agonist. After testing, pups were examined for sedation and other drug-related effects. The results indicated that all doses of buspirone reduced USV rates in isolation, consistent with other reports. PRX-00023 significantly reduced USV rates at the lowest doses (0.01–0.05 mg/kg). None of the PRX-00023 doses produced sedation, whereas all but the lowest dose of buspirone (0.1 mg/kg) produced sedation effects. The results suggest that this compound alleviates infantile anxiety-like behavior with great specificity in rats bred for high anxiety/depressive phenotypes by selectively targeting 5-HT1A receptors, possibly by both pre- and post-synaptic mechanisms.
17 citations
TL;DR: Growth factors such as IGF I could be considered for the systemic treatment of various bone disorders, or drugs could be developed to modify the synthesis or activity of the locally produced factors.
17 citations
Authors
Showing all 1697 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Steven M. Greenberg | 105 | 488 | 44587 |
| Linus Pauling | 100 | 536 | 63412 |
| Ernesto Canalis | 98 | 331 | 30085 |
| John S. Gottdiener | 94 | 316 | 49248 |
| Dalane W. Kitzman | 93 | 474 | 36501 |
| Joseph F. Polak | 91 | 406 | 38083 |
| Charles A. Boucher | 90 | 549 | 31769 |
| Lawrence G. Raisz | 82 | 315 | 26147 |
| Julius M. Gardin | 76 | 253 | 38063 |
| Jeffrey S. Hyams | 72 | 357 | 22166 |
| James J. Vredenburgh | 65 | 280 | 18037 |
| Michael Centrella | 62 | 120 | 11936 |
| Nathaniel Reichek | 62 | 248 | 22847 |
| Gerard P. Aurigemma | 59 | 212 | 17127 |
| Thomas L. McCarthy | 57 | 107 | 10167 |