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Institution

Saint Francis University

EducationLoretto, Pennsylvania, United States
About: Saint Francis University is a education organization based out in Loretto, Pennsylvania, United States. It is known for research contribution in the topics: Population & Osteoblast. The organization has 1694 authors who have published 2038 publications receiving 87149 citations.


Papers
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Journal ArticleDOI
02 Aug 2015
TL;DR: A 62-year-old female patient with HER2 + positive breast cancer presented to the emergency room with acute heart failure symptoms after trastuzumab use, and the patient symptoms resolved quickly with diuretic therapy and Trastuzuab was discontinued.
Abstract: Background: Trastuzumab-induced cardiotoxicity has been well accepted. Cardiotoxicity especially with concomitant or sequential use of anthracycline has been clinically identified as decreased left ventricular ejection fraction with or without symptoms of heart failure. Acute diastolic heart failure has not been reported. Case report : A 62-year-old female patient with HER2 + positive breast cancer presented to the emergency room with acute heart failure symptoms after trastuzumab use. Chest X-ray and CT demonstrated acute pulmonary edema. Echocardiography showed normal left ventricular ejection fraction, elevated left ventricular filling pressure, and moderate pulmonary hypertension, which are consistent with acute diastolic heart failure. The patient symptoms resolved quickly with diuretic therapy and Trastuzumab was discontinued. A follow-up echocardiography showed normal left and right ventricular function and a follow-up right heart catheterization demonstrated normal cardiac filling pressure and normal cardiac index. Conclusions: Trastuzumab induced cardiac toxicity could occur in a spectrum - from transient diastolic heart failure to systolic heart failure. The monitoring of both diastolic and systolic function during the course of trastuzumab treatment with or without other chemotherapy agents should be considered. Normal 0 false false false EN-US ZH-CN X-NONE
Book ChapterDOI
01 Jan 2006
TL;DR: Thoracic outlet syndrome refers to the set of disorders attributed to compromise of the neurovascular structures passing through the thoracic outlets, which include the subclavian/axillary artery, corresponding vein, and brachial plexus fibers.
Abstract: Fibromyalgia (FM) is a common musculoskeletal syndrome characterized by generalized pain, fatigue, and a number of associated symptoms. The condition has formerly been called fibrositis and psychogenic rheumatism. The condition is con­fusing in that there is considerable overlap between FM symp­toms and those of other conditions such as myofascial pain syndrome, temporomandibular joint syndrome, and chronic fatigue syndrome.

Authors

Showing all 1697 results

NameH-indexPapersCitations
Steven M. Greenberg10548844587
Linus Pauling10053663412
Ernesto Canalis9833130085
John S. Gottdiener9431649248
Dalane W. Kitzman9347436501
Joseph F. Polak9140638083
Charles A. Boucher9054931769
Lawrence G. Raisz8231526147
Julius M. Gardin7625338063
Jeffrey S. Hyams7235722166
James J. Vredenburgh6528018037
Michael Centrella6212011936
Nathaniel Reichek6224822847
Gerard P. Aurigemma5921217127
Thomas L. McCarthy5710710167
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20234
20228
2021146
2020133
2019126
201897