Saint Francis University

About: Saint Francis University is a education organization based out in Loretto, Pennsylvania, United States. It is known for research contribution in the topics: Population & Osteoblast. The organization has 1694 authors who have published 2038 publications receiving 87149 citations.

Safety and tolerance of lymph node biopsies from chronic HIV-1 volunteers in rural Tanzania.

Abstract: HIV-1 rapidly establishes a persistent infection that can be contained under life-long antiretroviral therapy (ART) but not cured. One major viral reservoir is the peripheral lymph node (LN) follicles. Studying the impact of novel HIV-1 treatment and vaccination approaches on cells residing in germinal centers is essential for rapid progress towards HIV-1 prevention and cure. We enrolled 9 asymptomatic adult volunteers with a newly diagnosed HIV-1 infection and CD4 T cell counts ≥ 350/ml. The patients underwent venous blood collection and inguinal lymph node excision surgery in parallel. Mononuclear cells were extracted from blood and tissues simultaneously. Participants were followed up regularly for 2 weeks until complete healing of the surgical wounds. All participants completed the lymph node excision surgery without clinical complications. Among the 9 volunteers, one elite controller was identified. The number of mononuclear cells recovered from lymph nodes ranged from 68 to 206 million and correlated positively with lymph node size. This is the first study to show that lymph node biopsy is a safe procedure and can be undertaken with local experts in rural settings. It provides a foundation for detailed immune response investigations during future clinical trials.

La modificabilidad estructural cognitiva en la familia de un enfermo alcohólico

Abstract: La teoria del Doctor Reuven Feuerstein, la Modifi cabilidad Estructural Cognitiva, sus criterios de mediacion para su Experienciade Aprendizaje y su Programa de Enriquecimiento Instrumental son elementos de gran utilidad para que la familia de un enfermo alcoholico pueda desarrollar estrategias de ayuda y acompanamiento al que bebe, y crezca de forma sana e integral como nucleo familiar con la guia del mediador, que en este caso es el especialista en adicciones. Por medio de preguntas generadoras, grupos focales, encuentros formativos para la familia, el mediador ampliara el conocimiento sobre alcoholismo, sus caracteristicas, el trato al enfermo, la codependencia de los familiares y la recuperacion adecuada de la totalidad de sus miembros, para que en ese proceso, a un ritmo propio, puedan modifi car ideas, reacciones, limites y aprobaciones a su familiar y a ellos mismos. Segun lo sugiere la teoria, el mediador sera solo un guia y provocador de la dinamica, esto se realizara por medio de pasos, principios psicopedagogicos, parametros y criterios de mediacion que trasmite la teoria.

Unlicenced cannabis-based product use in adult palliative medicine.

Abstract: Little is known about the prevalence of unlicenced cannabis-based product use in adult palliative care patients in the UK. Research in other jurisdictions where medicinal cannabis is legal has documented challenges with integration into clinical practice.1 The scheduling of these drugs in the UK changed in 2018.2 There remain few randomised controlled trials to support their use, which contributes to ongoing barriers to prescribing. At a hospice in London, we have been increasingly questioned by patients and families about the benefits of unlicenced forms of these products. Their usage appeared to be increasing in our geographical area. Anecdotally, they were …

Introduction to Simulation Learning in Emergency and Disaster Management

Abstract: Simulation and game-based learning is an essential learning application especially as it pertains to a high-stakes field like emergency and disaster management. Introducing real-life learning applications into the classroom allows the learner to make critical decisions at different points throughout a simulation providing practical learning that leads to a cognitive understanding of the material. These simulated practices ensure memory and longer retention of these events or tasks, a requirement to ensure that learning transpires. Likewise, these simulations also place the learner under acute stress, something that replicates the stress felt during real-life disasters. Therefore, it is crucial to have students apply what they have learned in simulations as a demonstration of their learning. These learned skills are essential for students to be marketable and thrive in a career field where decision-making, problem-solving, and critical thinking are vital for their success.