Institution
Saint Francis University
Education•Loretto, Pennsylvania, United States•
About: Saint Francis University is a education organization based out in Loretto, Pennsylvania, United States. It is known for research contribution in the topics: Population & Osteoblast. The organization has 1694 authors who have published 2038 publications receiving 87149 citations.
Topics: Population, Osteoblast, Growth factor, Bone cell, Bone remodeling
Papers published on a yearly basis
Papers
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TL;DR: This article focuses on the use of PCT in patients with various degrees of chronic kidney disease in addition to various forms of dialysis, as chronic kidneys disease may alter baseline levels of P CT and thus result in inappropriate use ofPCT in this population.
Abstract: Procalcitonin (PCT) has been shown to be a useful surrogate marker in identifying patients with various bacterial infections. PCT has been studied as a diagnostic marker in differentiating bacterial pneumonia from other respiratory conditions such as chronic obstructive pulmonary disease exacerbations or viral pneumonia. Differentiating bacterial from nonbacterial pneumonia using PCT has shown to reduce antibiotic usage, length of stay, and antibiotic-related adverse effects. PCT has also been studied in patients with sepsis in an effort to reduce unnecessary antibiotic usage and decrease the length of antibiotic therapy. This article focuses on the use of PCT in patients with various degrees of chronic kidney disease in addition to various forms of dialysis, as chronic kidney disease may alter baseline levels of PCT and thus result in inappropriate use of PCT in this population.
70 citations
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Norfolk and Norwich University Hospital1, University of Lausanne2, University of Toronto3, Case Western Reserve University4, Cleveland Clinic5, Mayo Clinic6, New York Medical College7, Westchester Medical Center8, Pennsylvania State University9, Muğla University10, St. Vincent's Health System11, University of Cambridge12, Harvard University13, University of Antwerp14, Royal Gwent Hospital15, Stanford University16, University of New South Wales17, Katholieke Universiteit Leuven18, University of Ottawa19, Abertawe Bro Morgannwg University Health Board20, Duke University21, University of North Carolina at Chapel Hill22, University of Melbourne23, University of Texas at Austin24, Belfast Health and Social Care Trust25, The Chinese University of Hong Kong26, Dalhousie University27, Columbia University Medical Center28, Glasgow Royal Infirmary29, University Hospital Galway30, Cork University Hospital31, St Thomas' Hospital32, Toronto Western Hospital33, University of Barcelona34, Saint Francis University35, Hospital for Special Surgery36, Canterbury Hospital37, Maltepe University38, Radboud University Nijmegen39, Saarland University40, University of Pennsylvania41
TL;DR: In this paper, the authors conducted an international consensus study involving experts using a three-round Delphi method to produce a list of names and corresponding descriptions of anatomical targets for abdominal wall, chest wall, and paraspinal blocks.
70 citations
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TL;DR: When combined in multivariate models, RLA Level, CT scan, ventilation time and aspiration emerged as significant independent predictors of impaired oral intake.
Abstract: Safe and adequate nutrition, vital to the recovery from a traumatic brain injury, can be severely compromised by the presence of dysphagia. This study identified injury severity and swallowing factors that were associated with impaired oral intake in patients with severe brain injury. An admitting G
69 citations
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TL;DR: PDGF BB stimulates IL- 6 expression in Ob cells, a response that is PKC and calcium dependent, and the increase in IL-6 expression may be relevant to the actions of PDGF BB on bone resorption.
Abstract: Platelet-derived growth factor (PDGF) increases bone resorption and the number of osteoclasts in calvarial sections, and it may regulate local cytokines involved in bone remodeling. Interleukin-6 (IL-6), a cytokine secreted by osteoblasts, osteoclasts, and stromal cells, is known to increase osteoclast recruitment. We tested the effects of PDGF on IL-6 expression in cultures of osteoblast-enriched cells from 22-day-old fetal rat calvariae (Ob cells). Treatment of Ob cells with PDGF BB caused a time- and dose-dependent induction of IL-6 messenger RNA (mRNA), as determined by Northern blot analysis. The effect was maximal after 1 h of treatment and was observed with PDGF BB at 0.3-3.3 nM. Treatment with PDGF BB for 24 h also increased IL-6 polypeptide levels in the culture medium, as determined by a specific bioassay. Although PDGF AA increased IL-6 mRNA levels, its effect was less pronounced than that of PDGF BB. Phorbol 12-myristate 13-acetate (PMA) induced IL-6 transcripts, and the effect of PDGF BB was ...
69 citations
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TL;DR: Episodes of disorientation and fall history were the best predictors of pediatric falls for this sample and the Morse Fall Scale's sensitivity, specificity and false positive rate suggested that the scale does little better than chance at detecting true fallers and may inaccurately identify non-fallers as high risk.
Abstract: Purpose To identify risk factors in hospitalized children using two validated adult fall risk scales. Methods For each fall patient identified, a non-fall patient was matched for chronological age and year of hospitalization. The retrospective chart review coded the presence or absence of risk factors and completed both the Morse Fall Scale and Hendrich II Fall Risk Model. Findings Overall, a significant difference was detected between pediatric fallers and non-fallers on the Morse Fall Scale. The Morse Fall Scale's sensitivity, specificity and false positive rate suggested that the scale does little better than chance at detecting true fallers and may inaccurately identify non-fallers as high risk. Conclusions Episodes of disorientation and fall history were the best predictors of pediatric falls for this sample.
69 citations
Authors
Showing all 1697 results
Name | H-index | Papers | Citations |
---|---|---|---|
Steven M. Greenberg | 105 | 488 | 44587 |
Linus Pauling | 100 | 536 | 63412 |
Ernesto Canalis | 98 | 331 | 30085 |
John S. Gottdiener | 94 | 316 | 49248 |
Dalane W. Kitzman | 93 | 474 | 36501 |
Joseph F. Polak | 91 | 406 | 38083 |
Charles A. Boucher | 90 | 549 | 31769 |
Lawrence G. Raisz | 82 | 315 | 26147 |
Julius M. Gardin | 76 | 253 | 38063 |
Jeffrey S. Hyams | 72 | 357 | 22166 |
James J. Vredenburgh | 65 | 280 | 18037 |
Michael Centrella | 62 | 120 | 11936 |
Nathaniel Reichek | 62 | 248 | 22847 |
Gerard P. Aurigemma | 59 | 212 | 17127 |
Thomas L. McCarthy | 57 | 107 | 10167 |