scispace - formally typeset
Search or ask a question
Institution

Saint Francis University

EducationLoretto, Pennsylvania, United States
About: Saint Francis University is a education organization based out in Loretto, Pennsylvania, United States. It is known for research contribution in the topics: Population & Osteoblast. The organization has 1694 authors who have published 2038 publications receiving 87149 citations.


Papers
More filters
Journal ArticleDOI
TL;DR: Although 6 min walk distance is shorter in obese COPD patients, their physiologic responses are similar to those of non-obese patients.

43 citations

Journal ArticleDOI
TL;DR: Panitumumab may represent an alternative treatment strategy for patients with refractory mCRC who have experienced failure with standard therapy including cetuximab-based regimens and may exert their antitumor activity through different mechanisms.

43 citations

Journal ArticleDOI
TL;DR: The overall prevalence of HIV infection and syphilis found among pregnant women attending ANC clinics in Tanzania calls for further strengthening of current intervention measures, which include scaling up the integration of prevention of mother to child transmission (PMTCT) services in Reproductive and Child Health clinics.
Abstract: The occurrence of HIV-1 and syphilis infections during pregnancy poses major health risks to the foetus due to mother-to-child transmission. We conducted surveillance of HIV and syphilis infections among pregnant women attending antenatal clinics (ANCs) in Mainland Tanzania in 2011. This surveillance was carried out in 133 ANCs selected from 21 regions in Tanzania. In each region, six ANC sites were selected, with urban, semi-urban, and rural areas contributing two each. All pregnant women who were attending selected sentinel ANC sites for the first time at any pregnancy between September and December 2011 were enrolled. Serial ELISA assays were performed to detect HIV infection in an unlinked anonymous manner using dried blood spot (DBS) after routine syphilis testing. Data analysis was conducted using Stata v.12 software. A total of 39,698 pregnant women representing 2.4 % of all pregnant women (1.68 million) attending ANCs in the Mainland Tanzania were enrolled. The overall HIV prevalence was found to be 5.6 % (95 % CI: 5.4–5.8 %). The risk for HIV infection was significantly higher among women aged 25–34 (cOR = 1.97, 95 % CI: 1.79–2.16; p < 0.05), older than 35 years (cOR = 1.88, 95 % CI: 1.62–2.17; p < 0.05) and those having 1–2 and 3–4 previous pregnancies. HIV infection was less prevalent among women attending rural ANC clinics (cOR = 0.46, 95 % CI 0.4–0.52; p < 0.05). The overall syphilis prevalence was 2.5 % (95 % CI: 2.3, 3.6). The risk for syphilis infection was significantly higher among women attending semi-urban and rural clinics and those having 3–4, and 5 previous pregnancies (p < 0.05). Marital status and level of education were not statistically significant with either of the two infections. HIV and syphilis co-infections occurred in 109 of 38,928 (0.3 %). The overall prevalence of HIV infection (5.6 %) and syphilis (2.5 %) found among pregnant women attending ANC clinics in Tanzania calls for further strengthening of current intervention measures, which include scaling up the integration of prevention of mother to child transmission (PMTCT) services in Reproductive and Child Health (RCH) clinics.

43 citations

Journal ArticleDOI
TL;DR: It is estimated that H. amphibius in this hydrologically altered watershed reduces dry-season fish abundance and indices of gamma-level diversity by 41% and 16%, respectively, but appears to promote aquatic invertebrate diversity.
Abstract: Cross-boundary transfers of nutrients can profoundly shape the ecology of recipient systems. The common hippopotamus, Hippopotamus amphibius, is a significant vector of such subsidies from terrestrial to river ecosystems. We compared river pools with high and low densities of H. amphibius to determine how H. amphibius subsidies shape the chemistry and ecology of aquatic communities. Our study watershed, like many in sub-Saharan Africa, has been severely impacted by anthropogenic water abstraction reducing dry-season flow to zero. We conducted observations for multiple years over wet and dry seasons to identify how hydrological variability influences the impacts of H. amphibius. During the wet season, when the river was flowing, we detected no differences in water chemistry and nutrient parameters between pools with high and low densities of H. amphibius. Likewise, the diversity and abundance of fish and aquatic insect communities were indistinguishable. During the dry season, however, high-density H. amphibius pools differed drastically in almost all measured attributes of water chemistry and exhibited depressed fish and insect diversity and fish abundance compared with low-density H. amphibius pools. Scaled up to the entire watershed, we estimate that H. amphibius in this hydrologically altered watershed reduces dry-season fish abundance and indices of gamma-level diversity by 41% and 16%, respectively, but appears to promote aquatic invertebrate diversity. Widespread human-driven shifts in hydrology appear to redefine the role of H. amphibius, altering their influence on ecosystem diversity and functioning in a fashion that may be more severe than presently appreciated.

42 citations

Journal ArticleDOI
TL;DR: In this article, the authors identify high-strength AMD discharges from both operating and abandoned portals as well as tailings-related deposits with a high degree of heterogeneity with total metal concentrations ranging from 0.11 to 7480, <0.022 to 889, < 0.0006 to 65.3, ≥ 0.001 to 310, 0.12 to 72,100, ≤ 0.3 to 402, ≤0.012 to 34.8, and ≤ 0 0.94 standard units, respectively.
Abstract: Intensive mining and processing of Ag, Sn, Pb and Zn ores have occurred in various locations within and around the city of Potosi, Bolivia since 1545. Surface and subsurface waters, stream sediments and soils are contaminated with various ecotoxic metals in the headwaters of the economically vital, yet highly impacted, upper Rio Pilcomayo watershed. Previous studies have documented downstream trace metal contamination, however, not addressed specific sources. The AMD discharges identified in this study help link downstream pollution to primary origins. The majority of AMD would be considered high-strength due to metal concentrations and acidity orders of magnitude greater than typical AMD. Discharges from both operating and abandoned portals as well as tailings-related deposits displayed a high degree of heterogeneity with total metal concentrations ranging from 0.11 to 7480, <0.022 to 889, <0.0006 to 65.3, <0.001 to 310, 0.12 to 72,100, 0.3 to 402, <0.012 to 34.8, and 0.24 to 19,600 mg/L of Al, As, Cd, Cu, Fe, Mn, Pb and Zn, respectively. Net acidity and pH ranged from −10 to 246,000 mg/L as CaCO3 equivalent and 0.90–6.94 standard units, respectively. Data were gathered during two sampling events centered around the most extreme periods of the dry and wet seasons of one water-year. Loadings to local streams were marginally greater for most metals in the wet season. If observed loadings are historically representative, Cerro Rico AMD has contributed thousands of tonnes of ecotoxic metals to the upper Rio Pilcomayo over the last five centuries. Metal and hydrogen ion concentrations in the majority of AMD sampled were several orders of magnitude above discharge limits set by the Bolivian government, yet no action has historically or contemporarily been taken.

42 citations


Authors

Showing all 1697 results

NameH-indexPapersCitations
Steven M. Greenberg10548844587
Linus Pauling10053663412
Ernesto Canalis9833130085
John S. Gottdiener9431649248
Dalane W. Kitzman9347436501
Joseph F. Polak9140638083
Charles A. Boucher9054931769
Lawrence G. Raisz8231526147
Julius M. Gardin7625338063
Jeffrey S. Hyams7235722166
James J. Vredenburgh6528018037
Michael Centrella6212011936
Nathaniel Reichek6224822847
Gerard P. Aurigemma5921217127
Thomas L. McCarthy5710710167
Network Information
Related Institutions (5)
Kent State University
24.6K papers, 720.3K citations

78% related

Baylor University
21.9K papers, 750.6K citations

76% related

University of North Carolina at Greensboro
13.7K papers, 456.2K citations

75% related

Ohio University
25.9K papers, 662.2K citations

75% related

University of South Carolina
59.9K papers, 2.2M citations

75% related

Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20234
20228
2021146
2020133
2019126
201897