scispace - formally typeset
Search or ask a question
Institution

Saint Louis University

EducationSt Louis, Missouri, United States
About: Saint Louis University is a education organization based out in St Louis, Missouri, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 18927 authors who have published 34895 publications receiving 1267475 citations. The organization is also known as: SLU & St. Louis University.


Papers
More filters
Journal ArticleDOI
TL;DR: PET can detect head and neck tumor recurrence when it may be undetectable by other clinical methods and permits highly accurate detection of head and head cancer recurrence in the posttherapy period.
Abstract: PURPOSE: Earlier detection of head and neck cancer recurrence may improve survival. We evaluated the ability of [18F]fluorodeoxyglucose positron emission tomography (FDG-PET) to detect recurrence in a prospective trial using sequential PET scans. PATIENTS AND METHODS: Serial posttherapy FDG-PET was prospectively performed in 44 patients with stage III or IV head and neck cancer. PET was performed twice during the first posttreatment year (at 2 and 10 months after therapy) and thereafter as needed. After therapy, patients were grouped, based on tissue biopsies, into those who achieved a complete response (CR) and those who had residual disease (RD). Patients who achieved a CR were further grouped into those without evidence of disease and those who had recurrence by 1 year after completion of therapy. Disease status as determined by physical examination (PE), PET, and correlative imaging was compared. RESULTS: Eight patients were lost to follow-up and six had RD after therapy. Of the remaining 30 patients ...

233 citations

Journal ArticleDOI
09 Feb 2011-JAMA
TL;DR: To quantify the relationship between peak post-CABG elevation of biomarkers of myocardial damage and early, intermediate-, and long-term mortality, including determining whether there is a threshold below which elevations lack prognostic significance, a large number of patients undergoing CABG surgery were surveyed.
Abstract: confidenceinterval[CI],0.36%-1.02%)for0to1,0.86%(95%CI,0.49%-1.40%)for 1t o2, 0.95% (95% CI, 0.72%-1.22%) for 2 to 5, 2.09% (95% CI, 1.69%-2.57%) for5to10,2.78%(95%CI,2.12%-3.58%)for10to20,and7.06%(95%CI,5.46%8.96%) for 20 to 40. Of the variables considered, the CK-MB ratio was the strongest independent predictor of death to 30 days and remained significant even after adjusting for a wide range of baseline risk factors (

233 citations

Journal ArticleDOI
TL;DR: Results from this study suggest that the HCV core protein plays a role in the inhibition of TNF-α-mediated cell death, which may provide a selective advantage for HCV replication, allowing for evasion of host antiviral defense mechanisms.

232 citations

Journal ArticleDOI
TL;DR: Elderly patients with chronic illnesses were more satisfied with their primary care physicians and outpatient visits when advanced directives were discussed, and the improvement in visit satisfaction was substantial and persistent.
Abstract: BACKGROUND: Discussions of end-of-life care should be held prior to acute, disabling events. Many barriers to having such discussions during primary care exist. These barriers include time constraints, communication difficulties, and perhaps physicians’ anxiety that patients might react negatively to such discussions.

232 citations

Journal ArticleDOI
TL;DR: What the 1918 virus teaches us about avian H5N1 influenza is described by Dr. Robert Belshe.
Abstract: The 1918 virus spread rapidly around the world and was associated with mortality measured in the thousands per 100,000 population. Dr. Robert Belshe describes what the 1918 virus teaches us about avian H5N1 influenza.

232 citations


Authors

Showing all 19076 results

NameH-indexPapersCitations
Douglas G. Altman2531001680344
John E. Morley154137797021
Roberto Romero1511516108321
Daniel S. Berman141136386136
Gregory J. Gores14168666269
Thomas J. Smith1401775113919
Richard T. Lee13181062164
George K. Aghajanian12127748203
Reza Malekzadeh118900139272
Robert N. Weinreb117112459101
Leslee J. Shaw11680861598
Thomas J. Ryan11667567462
Josep M. Llovet11639983871
Robert V. Farese11547348754
Michael Horowitz11298246952
Network Information
Related Institutions (5)
University of Pittsburgh
201K papers, 9.6M citations

95% related

University of North Carolina at Chapel Hill
185.3K papers, 9.9M citations

95% related

Yale University
220.6K papers, 12.8M citations

94% related

Duke University
200.3K papers, 10.7M citations

94% related

University of California, San Francisco
186.2K papers, 12M citations

94% related

Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202344
2022233
20211,618
20201,600
20191,457
20181,375