scispace - formally typeset
Search or ask a question
Institution

Saint Louis University

EducationSt Louis, Missouri, United States
About: Saint Louis University is a education organization based out in St Louis, Missouri, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 18927 authors who have published 34895 publications receiving 1267475 citations. The organization is also known as: SLU & St. Louis University.


Papers
More filters
Journal ArticleDOI
TL;DR: Intrapartum-related neonatal deaths can be substantially reduced by improving the quality of services for all childbirths that occur in health facilities, identifying and addressing the missed opportunities to provide effective interventions to those who seek facility-based care, and improving community-based services.

214 citations

Journal ArticleDOI
TL;DR: It is suggested that HCV genotype 1a (clone H77) can be serially passaged in IHH and thatHCV infection induces an autophagic response in hepatocytes.
Abstract: We have previously reported that immortalized human hepatocytes (IHH) support the generation of infectious hepatitis C virus (HCV) genotype 1a (clone H77). In the present study, we have investigated the growth of HCV genotype 1a (clone H77) through serial passages and accompanying changes in IHH in response to infection. Eleven serial passages of HCV genotype 1a (clone H77) in IHH were completed. Virus replication was ascertained from the presence of HCV-specific sequences, the detection of core antigen, the virus genome copy number, and the virus titer in IHH culture fluid. Electron microscopy suggested that HCV infection induces autophagic vacuole formation in IHH. Fluorescence microscopy displayed localization of autophagic markers, microtubule-associated protein-1 light chain-3 and Apg5, on the vacuoles of HCV-infected hepatocytes. Taken together, our results suggested that HCV genotype 1a (clone H77) can be serially passaged in IHH and that HCV infection induces an autophagic response in hepatocytes.

214 citations

Journal ArticleDOI
TL;DR: In this paper, the authors evaluated clinical outcomes and safety of EUS-guided drainage of pancreatic pseudocysts and walled-off necrosis (WON) by using a novel lumen-apposing, fully covered, self-expandable metal stent.

214 citations

Journal ArticleDOI
TL;DR: The NAPS2 consortium has successfully completed a prospective ascertainment of 1,000 subjects with RAP and CP from the USA, and these data will be useful in elucidating the environmental, metabolic and genetic conditions, and to investigate the complex interactions that underlie R AP and CP.

214 citations

Journal ArticleDOI
TL;DR: A soluble adenosine triphosphatase was obtained from skeletal muscle microsomes by extraction with deoxycholate and trypsin treatment causes the rapid release of proteins from microsome accompanied by decreased turbidity and an activation of ATPase activity.

214 citations


Authors

Showing all 19076 results

NameH-indexPapersCitations
Douglas G. Altman2531001680344
John E. Morley154137797021
Roberto Romero1511516108321
Daniel S. Berman141136386136
Gregory J. Gores14168666269
Thomas J. Smith1401775113919
Richard T. Lee13181062164
George K. Aghajanian12127748203
Reza Malekzadeh118900139272
Robert N. Weinreb117112459101
Leslee J. Shaw11680861598
Thomas J. Ryan11667567462
Josep M. Llovet11639983871
Robert V. Farese11547348754
Michael Horowitz11298246952
Network Information
Related Institutions (5)
University of Pittsburgh
201K papers, 9.6M citations

95% related

University of North Carolina at Chapel Hill
185.3K papers, 9.9M citations

95% related

Yale University
220.6K papers, 12.8M citations

94% related

Duke University
200.3K papers, 10.7M citations

94% related

University of California, San Francisco
186.2K papers, 12M citations

94% related

Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202344
2022233
20211,618
20201,600
20191,457
20181,375