Sao Paulo State University

About: Sao Paulo State University is a education organization based out in São Paulo, Brazil. It is known for research contribution in the topics: Population & Large Hadron Collider. The organization has 55715 authors who have published 100436 publications receiving 1375332 citations.

Antimicrobial activity of essential oils

Abstract: Natural products have been studied aiming to understand their biological properties Thus, this study aimed to investigate the antimicrobial activity of twenty-seven essential oils (EOs) used in aromatherapy procedures, a natural therapy with great emphasis currently used against Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa strains The agar dilution method was carried out and minimal inhibitory concentration against 50% and 90% of strains (MIC50% and MIC90% values) were reported The S aureus strains were highly susceptible with MIC90% from 021 mg/mL to black pepper (Piper nigrum) and tea tree (Melaleuca alternifolia) to 2652 mg/mL with copaiba (Copaifera officinalis) EO Cinnamon (Cinnamomum cassia) and clove (Syzygium aromaticum) EOs were effective against E coli (20 mg/mL) while the S aromaticum EO was against P aeruginosa (829 mg/mL) Thus, the higher susceptibility of Gram-positive bacteria when compared with Gram-negative strains was found, and a large variability in t

Effect of different probiotics on broiler carcass and meat quality

Abstract: The present work evaluated the effect of different probiotics on carcass and meat quality of broilers. One thousand and fifty male Cobb chicks were distributed at one day of age in a randomized design with 3 x 2 + 1 factorial arrangement (3 probiotics, 2 levels of probiotics in drinking water and 1 negative control group), using 5 replications with 30 birds. Carcass yield was higher (p<0.05) in control birds. Nevertheless, the groups fed with probiotics showed higher (p<0.01) leg yield at 45 days of age. There was a significant decrease in color (lightness) and increase in pH of breast muscle 5 hours after slaughter in the probiotics treated birds. In the sensory analysis, meat flavor and general aspect 72 hours after slaughter were better when probiotics were added in both water and diet. There were no differences in water holding capacity, cooking loss and shearing force among different probiotics or between them and the control. Thus, meat quality was better when probiotics were fed in the water and diet instead of only in the diet. Nevertheless, carcass and meat quality showed no alteration when the control group was compared to birds fed with probiotics, except for leg yield improvement in the latter.

Long-term carbon loss in fragmented Neotropical forests

Abstract: Tropical forest deforestation is a major source of CO2 emissions, yet potential additional emissions through the creation of forest edge areas has been largely overlooked. Here, the authors combine remote sensing and knowledge on spatial processes to estimate carbon loss due to forest fragmentation.

A novel mutation (Q40P) in PAX8 associated with congenital hypothyroidism and thyroid hypoplasia: evidence for phenotypic variability in mother and child.

Abstract: Congenital hypothyroidism associated with thyroid hypoplasia can be caused by several genetic defects, including mutations in the TSHβ-subunit, the TSH receptor, the Gsα-subunit, and the transcription factor PAX8. Four girls with sporadic congenital hypothyroidism and hypoplastic thyroid glands were analyzed for mutations in PAX8 and TTF2 (FKHL15). Mutations in the coding region of the TSHβ-subunit gene, the TSH receptor gene, and exons 8 and 9 of Gsα had been excluded previously. Serum TSH concentrations were 150 mU/liter or more, TG levels were within normal limits, and thyroid autoantibodies were absent. Technetium scintigraphies did not reveal the presence of thyroid tissue, but ultrasonography documented hypoplastic, normally located glands. One patient was found to harbor a heterozygous transversion 119A→C in exon 3 of PAX8 replacing a conserved glutamine by proline in the paired box domain (Q40P). Analysis of her family members revealed that her mother, who has a thyroid gland of normal size and mi...