Institution
Sao Paulo State University
Education•São Paulo, Brazil•
About: Sao Paulo State University is a education organization based out in São Paulo, Brazil. It is known for research contribution in the topics: Population & Context (language use). The organization has 55715 authors who have published 100436 publications receiving 1375332 citations.
Papers published on a yearly basis
Papers
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Vardan Khachatryan, Albert M. Sirunyan, Armen Tumasyan, Wolfgang Adam1 +2155 more•Institutions (136)
TL;DR: The first measurement of the cross section for top-quark pair production in pp collisions at the LHC at center-of-mass energy sqrt(s)= 7 TeV has been performed using 3.1 {\pm} 0.3 inverse pb of data recorded by the CMS detector as discussed by the authors.
142 citations
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TL;DR: Environmental samples from the living area of symptomatic patients were analysed, proving that most environmental strains differed from known etiologic agents of pronounced disease syndromes: they belonged to the same order, but mostly were undescribed species.
142 citations
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TL;DR: It is demonstrated that hypoxia induces complex and cell type-specific pro-angiogenic responses and suggest that VEGF (but not bFGF) participates in the revascularization of hypoxic dental pulps.
142 citations
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TL;DR: It is concluded that absence of a functional AR in SC impedes the remodeling of testicular tubules expected at the onset of spermatogenesis and interferes with the creation of the specific environment needed for germ cell development.
Abstract: The observation that mice with a selective ablation of the androgen receptor (AR) in Sertoli cells (SC) (SCARKO mice) display a complete block in meiosis supports the contention that SC play a pivotal role in the control of germ cell development by androgens. To delineate the physiological and molecular mechanism responsible for this control, we compared tubular development in pubertal SCARKO mice and littermate controls. Particular attention was paid to differences in SC maturation, SC barrier formation and cytoskeletal organization and to the molecular mediators potentially involved. Functional analysis of SC barrier development by hypertonic perfusion and lanthanum permeation techniques and immunohistochemical analysis of junction formation showed that SCARKO mice still attempt to produce a barrier separating basal and adluminal compartment but that barrier formation is delayed and defective. Defective barrier formation was accompanied by disturbances in SC nuclear maturation (immature shape, absence of prominent, tripartite nucleoli) and SC polarization (aberrant positioning of SC nuclei and cytoskeletal elements such as vimentin). Quantitative RT-PCR was used to study the transcript levels of genes potentially related to the described phenomena between day 8 and 35. Differences in the expression of SC genes known to play a role in junction formation could be shown from day 8 for Cldn11, from day 15 for Cldn3 and Espn, from day 20 for Cdh2 and Jam3 and from day 35 for ZO-1. Marked differences were also noted in the transcript levels of several genes that are also related to cell adhesion and cytoskeletal dynamics but that have not yet been studied in SC (Actn3, Ank3, Anxa9, Scin, Emb, Mpzl2). It is concluded that absence of a functional AR in SC impedes the remodeling of testicular tubules expected at the onset of spermatogenesis and interferes with the creation of the specific environment needed for germ cell development.
142 citations
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01 Mar 2002TL;DR: Data suggest an increase in the fungicidal activity of macrophages by propolis stimulation, independently from its geographic origin.
Abstract: Paracoccidioidomycosis is the most important systemic mycosis in Latin America. Its etiological agent, Paracoccidoides brasiliensis, affects individuals living in endemic areas through inhalation of airborne conidia or mycelial fragments. The disease may affect different organs and systems, with multiple clinical features, with cell-mediated immunity playing a significant role in host defence. Peritoneal macrophages from BALB/c mice were stimulated with Brazilian or Bulgarian propolis and subsequently challenged with P. brasiliensis. Data suggest an increase in the fungicidal activity of macrophages by propolis stimulation, independently from its geographic origin.
142 citations
Authors
Showing all 56201 results
Name | H-index | Papers | Citations |
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Russel J. Reiter | 169 | 1646 | 121010 |
Tobin J. Marks | 159 | 1621 | 111604 |
Joseph T. Hupp | 141 | 731 | 82647 |
Luca Lista | 140 | 2044 | 110645 |
Sergio F Novaes | 138 | 1559 | 101941 |
Wagner Carvalho | 135 | 1395 | 94184 |
Alberto Santoro | 135 | 1576 | 100629 |
Andre Sznajder | 134 | 1464 | 98242 |
Luiz Mundim | 133 | 1413 | 89792 |
Eduardo De Moraes Gregores | 133 | 1454 | 92464 |
Helio Nogima | 132 | 1274 | 84368 |
Pedro G Mercadante | 129 | 1331 | 86378 |
D. De Jesus Damiao | 128 | 1162 | 82707 |
Sandra S. Padula | 128 | 1131 | 77174 |
Sudha Ahuja | 127 | 1016 | 75739 |