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Institution

Sapienza University of Rome

EducationRome, Lazio, Italy
About: Sapienza University of Rome is a education organization based out in Rome, Lazio, Italy. It is known for research contribution in the topics: Population & Medicine. The organization has 62002 authors who have published 155468 publications receiving 4397244 citations. The organization is also known as: La Sapienza & Università La Sapienza di Roma.


Papers
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Journal ArticleDOI
TL;DR: A dual origin for the first Americans is a striking novelty from the genetic point of view, and it makes plausible a scenario positing that within a rather short period of time, there may have been several entries into the Americas from a dynamically changing Beringian source.

633 citations

Journal ArticleDOI
TL;DR: This paper considers an MIMO multicell system where multiple mobile users ask for computation offloading to a common cloud server, and proposes an iterative algorithm, based on a novel successive convex approximation technique, converging to a local optimal solution of the original nonconvex problem.
Abstract: Migrating computational intensive tasks from mobile devices to more resourceful cloud servers is a promising technique to increase the computational capacity of mobile devices while saving their battery energy. In this paper, we consider a MIMO multicell system where multiple mobile users (MUs) ask for computation offloading to a common cloud server. We formulate the offloading problem as the joint optimization of the radio resources-the transmit precoding matrices of the MUs-and the computational resources-the CPU cycles/second assigned by the cloud to each MU-in order to minimize the overall users' energy consumption, while meeting latency constraints. The resulting optimization problem is nonconvex (in the objective function and constraints). Nevertheless, in the single-user case, we are able to express the global optimal solution in closed form. In the more challenging multiuser scenario, we propose an iterative algorithm, based on a novel successive convex approximation technique, converging to a local optimal solution of the original nonconvex problem. Then, we reformulate the algorithm in a distributed and parallel implementation across the radio access points, requiring only a limited coordination/signaling with the cloud. Numerical results show that the proposed schemes outperform disjoint optimization algorithms.

632 citations

Journal ArticleDOI
TL;DR: These expert consensus recommendations can be used as clinical guidelines for primary staging and restaging of rectal cancer using MRI and were constructed through consensus amongst 14 abdominal imaging experts.
Abstract: The article Magnetic resonance imaging for clinical management of rectal cancer: Updated recommendations from the 2016 European Society of Gastrointestinal and Abdominal Radiology (ESGAR) consensus meeting, written by [§§§ AuthorNames §§§].

631 citations

Journal ArticleDOI
TL;DR: HBV-related HCCs may arise on non-cirrhotic livers, further supporting the notion that HBV plays a direct role in liver transformation by triggering both common and etiology specific oncogenic pathways in addition to stimulating the host immune response and driving liver chronic necro-inflammation.

631 citations

Journal ArticleDOI
TL;DR: It is shown that the main indigenous North African cluster is a sister group to the most ancient cluster of European mtDNAs, from which it diverged approximately 50,000 years ago.
Abstract: Variation in the human mitochondrial genome (mtDNA) is now routinely described and used to infer the histories of peoples, by means of one of two procedures, namely, the assaying of RFLPs throughout the genome and the sequencing of parts of the control region (CR). Using 95 samples from the Near East and northwest Caucasus, we present an analysis based on both systems, demonstrate their concordance, and, using additional available information, present the most refined phylogeny to date of west Eurasian mtDNA. We describe and apply a nomenclature for mtDNA clusters. Hypervariable nucleotides are identified, and the relative mutation rates of the two systems are evaluated. We point out where ambiguities remain. The identification of signature mutations for each cluster leads us to apply a hierarchical scheme for determining the cluster composition of a sample of Berber speakers, previously analyzed only for CR variation. We show that the main indigenous North African cluster is a sister group to the most ancient cluster of European mtDNAs, from which it diverged ∼50,000 years ago.

630 citations


Authors

Showing all 62745 results

NameH-indexPapersCitations
Charles A. Dinarello1901058139668
Gregory Y.H. Lip1693159171742
Peter A. R. Ade1621387138051
H. Eugene Stanley1541190122321
Suvadeep Bose154960129071
P. de Bernardis152680117804
Bart Staels15282486638
Alessandro Melchiorri151674116384
Andrew H. Jaffe149518110033
F. Piacentini149531108493
Subir Sarkar1491542144614
Albert Bandura148255276143
Carlo Rovelli1461502103550
Robert C. Gallo14582568212
R. Kowalewski1431815135517
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023405
20221,106
20219,797
20209,755
20198,332
20187,615