Showing papers by "Saskatchewan Health published in 2007"
14 Mar 2007
62 citations
TL;DR: The ELISA based on recombinant baculovirus produced N protein of hMPV provides a useful tool for seroepidemiological study of this virus.
Abstract: Human metapneumovirus (hMPV) is a newly identified respiratory virus associated with respiratory tract infection in both adults and children Previous reports showed that infection of hMPV appeared to be ubiquitous To determine the seroprevalence of hMPV, a total of 576 human sera from patients in Saskatchewan, Canada, were screened by enzyme-linked immunosorbent assay (ELISA) based on expression of the nucleocapsid (N) protein of hMPV in recombinant baculovirus The recombinant N protein with a molecular mass of 435 kDa was abundantly produced in insect cells Moreover, the recombinant N proteins of the prototype viruses for the two major groups of hMPV have cross-antigenicity The seropositive rate for each age group was 135% (13/96) (0–5 years), 261% (25/96) (6–10 years), 323% (31/96) (11–15 years), 990% (95/96) (16–30 years), 917% (88/96) (31–60 years), and 938% (90/96) (61+ years), respectively The data indicated that exposure to hMPV is a common phenomenon The ELISA based on recombinant baculovirus produced N protein of hMPV provides a useful tool for seroepidemiological study of this virus J Med Virol 79:308–313, 2007 © 2007 Wiley-Liss, Inc
26 citations
TL;DR: An increasing trend in burden of direct health care costs associated with falls injury hospitalization among Saskatchewan senior residents is evident, which would have implications in planning and budgeting for future health care needs of the growing population of seniors in the province.
5 citations