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Institution

Shahid Beheshti University of Medical Sciences and Health Services

EducationTehran, Iran
About: Shahid Beheshti University of Medical Sciences and Health Services is a education organization based out in Tehran, Iran. It is known for research contribution in the topics: Population & Cancer. The organization has 19456 authors who have published 33659 publications receiving 365676 citations.


Papers
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Journal ArticleDOI
TL;DR: Increasing the taper of the root canal preparation can reduce fracture resistance and access cavity preparation can reduction resistance; however, CAC in comparison with TAC had no significant impact.

84 citations

Journal ArticleDOI
TL;DR: In this article, the antibacterial activity and biofilm inhibitory activity of Zataria multiflora-derived silver nanoparticles (AgNPs) compared to commercial AgNPs against Staphylococcus aureus ATCC 25923.

84 citations

Journal ArticleDOI
TL;DR: Fractional factorial design was applied to examine which variables affect the physicochemical properties of amikacin SLNs and showed that three quantitative factors, including the amount of lipid phase, ratio of drug to lipid, and volume of aqueous phase, were the most important variables on studied responses.
Abstract: Solid lipid nanoparticles (SLNs) have been studied as a drug-delivery system for the controlling of drug release. These colloidal systems have many important advantages, such as biocompatibility, good tolerability, and ease of scale-up. In the preparation of SLNs, many factors are involved in the characteristics of the particles, such as particle size, drug loading, and zeta potential. In this study, fractional factorial design was applied to examine which variables affect the physicochemical properties of amikacin SLNs. Study was continued by a statistical central composite design (CCD) to minimize particle size and maximize drug-loading efficiency of particles. The results showed that three quantitative factors, including the amount of lipid phase, ratio of drug to lipid, and volume of aqueous phase, were the most important variables on studied responses. The best predicted model for particle size was the quadratic model, and for drug-loading efficiency, was the linear model without any significant lack of fit. Optimum condition was achieved when the ratio of drug to lipid was set at 0.5, the amount of lipid phase at 314 mg, and the volume of aqueous phase at 229 mL. The optimized particle size was 149 +/- 4 nm and the drug-loading efficiency 88 +/- 5%. Polydispersity index was less than 0.3. The prepared particles had spherical shape, and the drug release from nanoparticles continued for 144 hours (6 days) without significant burst effect.

84 citations

Journal ArticleDOI
Abstract: Food packaging requires long shelf life and the monitoring of safety and quality based on international standards. In the past decade, polymer nanocomposites have emerged as a new class of food packaging materials, because they have several advantages, such as enhanced mechanical, thermal, and barrier properties. The larger surface area of nanoparticles compared with their microscale counterparts favours filler–matrix interactions and the performance of the resulting material. A new technology is accepted by the community once it has been tested for its effects on health. There have been some studies on the migration of nanoparticles from packaging material into food/food simulants during storage. It is very important to evaluate the safety of nanocomposite packaging materials used for food products. This review summarizes the characteristics and properties of nanocomposite packaging materials along with their safety problems for food consumers.

84 citations

Journal ArticleDOI
TL;DR: Due to the negative impact of hyperkyphosis on physical function, quality of life and mortality rates, physicians should focus not only on osteoporosis, but also on age-related postural changes.
Abstract: The present study aims to qualitatively review the contributing factors and health implications of age-related hyperkyphosis. We conducted a narrative review of observational and cohort studies describing the risk factors and epidemiology of hyperkyphosis from 1955 to 2016 using the following key words: kyphosis, hyperkyphosis, posture, age-related hyperkyphosis, kyphotic posture, aetiology and causes. This review included 77 studies. Approximately 60–70 % of the most severe hyperkyphosis cases have no evidence of underlying vertebral compression fractures. Other proposed factors contributing to hyperkyphosis are degenerative disc disease, weakness of back extensor muscles and genetic predisposition. Strength and endurance of back extensor muscles are very important for maintaining normal postural alignment. Recent evidence suggests that age-related hyperkyphosis is not equivalent to spinal osteoporosis. Due to the negative impact of hyperkyphosis on physical function, quality of life and mortality rates, physicians should focus not only on osteoporosis, but also on age-related postural changes. More research about the relationship between spinal morphology and modifiable factors, especially the structural and functional parameters of trunk muscles, could further illuminate our understanding and treatment options for hyperkyphosis.

84 citations


Authors

Showing all 19557 results

NameH-indexPapersCitations
Paul F. Jacques11444654507
Mohammad Abdollahi90104535531
Fereidoun Azizi80127941755
Roya Kelishadi7385333681
Nima Rezaei72121526295
Neal D. Freedman6832716908
Jamie E Craig6838015956
Amir Hossein Mahvi6368615816
Adriano G. Cruz6134612832
Ali Montazeri6162517494
Parvin Mirmiran5663715420
Harry A. Lando532429432
Fatemeh Atyabi533109985
Daniel Granato532359406
Pejman Rohani5219213386
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202332
2022187
20214,346
20204,415
20193,809
20183,480