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Institution

Shahid Beheshti University of Medical Sciences and Health Services

EducationTehran, Iran
About: Shahid Beheshti University of Medical Sciences and Health Services is a education organization based out in Tehran, Iran. It is known for research contribution in the topics: Population & Cancer. The organization has 19456 authors who have published 33659 publications receiving 365676 citations.


Papers
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Journal ArticleDOI
TL;DR: Astigmatism was the most common refractive errors in children and adults followed by hyperopia and myopia and the highest prevalence of myopia was seen in South-East Asian adults.
Abstract: Purpose The aim of the study was a systematic review of refractive errors across the world according to the WHO regions Methods To extract articles on the prevalence of refractive errors for this meta-analysis, international databases were searched from 1990 to 2016 The results of the retrieved studies were merged using a random effect model and reported as estimated pool prevalence (EPP) with 95% confidence interval (CI) Results In children, the EPP of myopia, hyperopia, and astigmatism was 117% (95% CI: 105–130), 46% (95% CI: 39–52), and 149% (95% CI: 127–171), respectively The EPP of myopia ranged from 49% (95% CI: 16–81) in South–East Asia to 182% (95% CI: 109–255) in the Western Pacific region, the EPP of hyperopia ranged from 22% (95% CI: 12–33) in South-East Asia to 143% (95% CI: 134–152) in the Americas, and the EPP of astigmatism ranged from 98% in South-East Asia to 272% in the Americas In adults, the EPP of myopia, hyperopia, and astigmatism was 265% (95% CI: 234–296), 309% (95% CI: 262–356), and 404% (95% CI: 343–466), respectively The EPP of myopia ranged from 162% (95% CI: 156–168) in the Americas to 329% (95% CI: 251–407) in South-East Asia, the EPP of hyperopia ranged from 231% (95% CI: 61%–402%) in Europe to 386% (95% CI: 224–548) in Africa and 372% (95% CI: 253–49) in the Americas, and the EPP of astigmatism ranged from 114% (95% CI: 21–207) in Africa to 456% (95% CI: 441–471) in the Americas and 448% (95% CI: 366–531) in South-East Asia The results of meta-regression showed that the prevalence of myopia increased from 1993 (104%) to 2016 (342%) (P = 0097) Conclusion This report showed that astigmatism was the most common refractive errors in children and adults followed by hyperopia and myopia The highest prevalence of myopia and astigmatism was seen in South-East Asian adults The highest prevalence of hyperopia in children and adults was seen in the Americas

244 citations

Journal ArticleDOI
TL;DR: High prevalence of complications among thalassemics signifies the importance of more detailed studies along with therapeutic interventions, and shows significant association with lumbar but not femoral BMD.
Abstract: The combination of transfusion and chelation therapy has dramatically extended the life expectancy of thalassemic patients. The main objective of this study is to determine the prevalence of prominent thalassemia complications. Two hundred twenty patients entered the study. Physicians collected demographic and anthropometric data and the history of therapies as well as menstrual histories. Patients have been examined to determine their pubertal status. Serum levels of 25(OH) D, calcium, phosphate, iPTH were measured. Thyroid function was assessed by T3, T4 and TSH. Zinc and copper in serum were determined by flame atomic absorption spectrophotometry. Bone mineral density (BMD) measurements at lumbar and femoral regions have been done using dual x-ray absorptiometry. The dietary calcium, zinc and copper intakes were estimated by food-frequency questionnaires. Short stature was seen in 39.3% of our patients. Hypogonadism was seen in 22.9% of boys and 12.2% of girls. Hypoparathyroidism and primary hypothyroidism was present in 7.6% and 7.7% of the patients. About 13 % of patients had more than one endocrine complication with mean serum ferritin of 1678 ± 955 micrograms/lit. Prevalence of lumbar osteoporosis and osteopenia were 50.7% and 39.4%. Femoral osteoporosis and osteopenia were present in 10.8% and 36.9% of the patients. Lumbar BMD abnormalities were associated with duration of chelation therapy. Low serum zinc and copper was observed in 79.6% and 68% of the study population respectively. Serum zinc showed significant association with lumbar but not femoral BMD. In 37.2% of patients serum levels of 25(OH) D below 23 nmol/l were detected. High prevalence of complications among our thalassemics signifies the importance of more detailed studies along with therapeutic interventions.

243 citations

Journal ArticleDOI
TL;DR: It is suggested that PRP injection is more efficacious than HA injection in reducing symptoms and improving quality of life and is a therapeutic option in select patients with knee OA who have not responded to conventional treatment.
Abstract: Introduction: Knee osteoarthritis (OA) is the most common articular disease. Different methods are used to alleviate the symptoms of patients with knee OA, including analgesics, physical therapy, exercise prescription, and intra-articular injections (glucocorticoids, hyaluronic acid [HA], etc). New studies have focused on modern therapeutic methods that stimulate cartilage healing process and improve the damage, including the use of platelet-rich plasma (PRP) as a complex of growth factors. Due to the high incidence of OA and its consequences, we decided to study the long-term effect of intra-articular injection of PRP and HA on clinical outcome and quality of life of patients with knee OA. Method: This non-placebo-controlled randomized clinical trial involved 160 patients affected by knee OA, grade 1–4 of Kellgren–Lawrence scale. In the PRP group (n = 87), two intra-articular injections at 4-week interval were applied, and in the HA group (n = 73), three doses of intra-articular injection at 1-week interval were applied. All patients were prospectively evaluated before and at 12 months after the treatment by Western Ontario and McMaster Universities Arthritis Index (WOMAC) and SF-36 questionnaires. The results were analyzed using SPSS 16.1 software (RCT code: IRCT2014012113442N5). Results: At the 12-month follow-up, WOMAC pain score and bodily pain significantly improved in both groups; however, better results were determined in the PRP group compared to the HA group (P < 0.001). Other WOMAC and SF-36 parameters improved only in the PRP group. More improvement (but not statistically significant) was achieved in patients with grade 2 OA in both the groups. Conclusion: This study suggests that PRP injection is more efficacious than HA injection in reducing symptoms and improving quality of life and is a therapeutic option in select patients with knee OA who have not responded to conventional treatment.

242 citations

Journal ArticleDOI
TL;DR: The antibacterial activity of cinnamon, thyme, and rosemary essential oils (EOs) and shallot and turmeric extracts was tested against L. monocytogenes and showed that thyme EO had the highest antimicrobial activity, followed by cinnamon androsemary EOs, respectively.

241 citations

Journal Article
TL;DR: DALYs due to HCV infection are increasing in Iran according to the Global Burden of Disease study 2010; however, the estimations of DALys using GBD 2010 are mostly from model-based data and there are significant uncertainties for extrapolated data.
Abstract: BACKGROUND: Hepatitis C virus (HCV) is the foremost cause of deaths attributable tocirrhosis and hepatocellular carcinoma. The Global Burden of Disease (GBD) study from 2010 quantifies and compares the degree of health loss as a result of diseases, injuries, and risk factors by age, sex, and geography overtime. This study aimed to present and critique the burden of hepatitis C and its trend in Iran between 1990 and 2010 by using the GBD 2010 study. METHODS: We used results of GBD 2010 between 1990 and 2010 for Iran to measure rates and trends for mortality, causes of deaths, years of life lost (YLLs), years lived with disability (YLDs), anddisability-adjusted lifeyears (DALYs). Hepatitis C was defined as the presence of hepatitis C virus in the serum. Data were presented in three categories: acute hepatitis C, cirrhosis secondary to hepatitis C, and liver cancer secondary to hepatitis C. RESULTS: HCV infection (including the three categories of the study) led to 57.29, 59.92, and 66.45 DALYs (per 100,000 population) in 1990, 2000, and 2010, respectively. DALYs and death rates showed a slight decreasing trend for HCV cirrhosis; however, DALYs and death rates increased for acute hepatitis and liver cancer due to patients with HCV. The majority of deaths and DALYs were in individuals aged 70 years and above in all three categories of HCV. YLLs made the greatest contributions to DALYs. CONCLUSION: DALYs due to HCV infection are increasing in Iran according to GBD 2010; however, the estimations of DALYs using GBD 2010 are mostly from model-based data and there are significant uncertainties for extrapolated data. In this regard, acomprehensive study such asthe National and Subnational Burden of Diseases (NASBOD) study would be needed to estimate and calculate precisely prevalence and burden of HCV-related disease at national and subnational levels.

238 citations


Authors

Showing all 19557 results

NameH-indexPapersCitations
Paul F. Jacques11444654507
Mohammad Abdollahi90104535531
Fereidoun Azizi80127941755
Roya Kelishadi7385333681
Nima Rezaei72121526295
Neal D. Freedman6832716908
Jamie E Craig6838015956
Amir Hossein Mahvi6368615816
Adriano G. Cruz6134612832
Ali Montazeri6162517494
Parvin Mirmiran5663715420
Harry A. Lando532429432
Fatemeh Atyabi533109985
Daniel Granato532359406
Pejman Rohani5219213386
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202332
2022187
20214,346
20204,415
20193,809
20183,480