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Institution

Shahid Beheshti University of Medical Sciences and Health Services

EducationTehran, Iran
About: Shahid Beheshti University of Medical Sciences and Health Services is a education organization based out in Tehran, Iran. It is known for research contribution in the topics: Population & Cancer. The organization has 19456 authors who have published 33659 publications receiving 365676 citations.


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Journal ArticleDOI
TL;DR: This paper introduces a novel partitioning algorithm that its initialization does not lead the algorithm to local optimum and can find all the Gaussian-shaped clusters if it has the right number of them.
Abstract: Clustering analysis is the process of dividing a set of objects into none-overlapping subsets. Each subset is a cluster, such that objects in the cluster are similar to one another and dissimilar to the objects in the other clusters. Most of the algorithms in partitioning approach of clustering suffer from trapping in local optimum and the sensitivity to initialization and outliers. In this paper, we introduce a novel partitioning algorithm that its initialization does not lead the algorithm to local optimum and can find all the Gaussian-shaped clusters if it has the right number of them. In this algorithm, the similarity between pairs of objects are computed once and updating the medoids in each iteration costs O(kxm) where k is the number of clusters and m is the number of objects needed to update medoids of the clusters. Comparison between our algorithm and two other partitioning algorithms is performed by using four well-known external validation measures over seven standard datasets. The results for the larger datasets show the superiority of the proposed algorithm over two other algorithms in terms of speed and accuracy.

78 citations

Journal ArticleDOI
TL;DR: The results of this multi-national study on hospitalized patients with Sars-CoV-2 infection indicated an overall stroke risk of 0.5% and the need for mechanical ventilation and the history of ischaemic heart disease are the independent predictors of stroke among SARS-Cov-2 patients.

78 citations

Journal ArticleDOI
01 Jun 2007-Cornea
TL;DR: Karatoconus is the most common indication for PK in Iran, and there was an increasing trend in rates of keratoconus and pseudophakic bullous keratopathy and a decreasing trend in aphakic Bullous Keratopathy over this period.
Abstract: PURPOSE To determine the indications for penetrating keratoplasty (PK) in Iran. METHODS : All eye bank records of patients who had undergone PK between 1994 and 2004 at ophthalmic centers throughout the country were reviewed. RESULTS During this 11-year period, a total of 19,668 cases were operated on. The most common indication for PK was keratoconus (n = 6787, 34.51%), followed by corneal opacity and scar (n = 3674, 18.68%), pseudophakic bullous keratopathy (n = 1808, 9.19%), corneal dystrophies (n = 1272, 6.47%), aphakic bullous keratopathy (n = 1198, 6.09%), and regraft (n = 1038, 5.28%). There was an increasing trend in rates of keratoconus and pseudophakic bullous keratopathy and a decreasing trend in aphakic bullous keratopathy over this period (P < 0.001). No significant change of trend was noted in the corneal opacity and scar, regraft, and corneal dystrophy groups. CONCLUSIONS Keratoconus is the most common indication for PK in Iran.

77 citations

Journal ArticleDOI
TL;DR: Compared to the WHO drinking water guidelines for Pb, Cd and As, virtually all the trace elements in the drinking water of villages in the present study could meet the requirements of the regulation except As in some villages.
Abstract: Water contamination by heavy metals has become a serious environmental issue due to its serious threat to human health. The current research was conducted to determine heavy metal concentrations in drinking groundwater samples in villages of Dehgolan, western Iran and to ascertain the potential health risk in terms of estimated non-carcinogenic risks by hazard quotient and hazard index and carcinogenic risk to the residents living in these areas from exposure to the metals via drinking water ingestion and skin contact routes. Health risks were conducted for resident adults based on the USEPA health risk assessment guidelines. The mean values of Pb, Cd, and As in the groundwater samples were 0.0026 mg/L (ranging from 0.0020–0.0030 mg/L), 0.0009 mg/L (ranging from 0.0007–0.0010 mg/L), and 0.0068 mg/L (ranging from 0.0011–0.0360 mg/L), respectively. Compared to the WHO drinking water guidelines for Pb, Cd and As, virtually all the trace elements in the drinking water of villages in the present study could meet the requirements of the regulation except As in some villages. The results of the study obtained in all cases demonstrated that the non-carcinogenic risk was below the safe limit. The calculated carcinogenic risk for adults obtained was all lower than USEPA’s acceptable cancer risk range of 1 × 10−4 to 1 × 10−6, suggesting no potential carcinogenic risk from drinking water consumption.

77 citations

Journal ArticleDOI
TL;DR: In vitro susceptibility of 75 clinical isolates of C. difficile to 5 antimicrobial agents, including metronidazole, vancomycin, clindamycin, erythromycin and cefotaxime was investigated by Clinical and Laboratory Standards Institute (CLSI) agar dilution method.
Abstract: Background: Clostridium difficile infection (CDI) is major growing problem in hospitals and its high incidence has been reported in recent years. Objectives: The aim of this study was to investigate the antimicrobial susceptibility patterns of C. difficile clinical isolates against antibiotics commonly used for treatment CDI in hospitalized patients. Material and Methods: During a 12 month study, 75 C. difficile isolates were collected from 390 patients with CDI. All samples were treated with alcohol and yeast extract broth. The treated suspensions were cultured on a selective cycloserine cefoxitin fructose agar (CCFA) supplemented with 5% sheep blood and incubated in anaerobic conditions, at 37 °C for 5 days. Cdd-3, tcdA and tcdB genes were identified using PCR assay. Results: The prevalence of A + B + , A + B - and A - B + strains were 64(85.3%), 5(6.7%) and 6(8%) respectively. In vitro susceptibility of 75 clinical isolates of C. difficile to 5 antimicrobial agents, including metronidazole, vancomycin, clindamycin, erythromycin and cefotaxime were investigated by Clinical and Laboratory Standards Institute (CLSI) agar dilution method. Metronidazole and vancomycin had good activity against C. difficile isolates with MIC90s of 2 and 1 µg/ml, respectively. Seventy one (94.6%) of strains was inhibited by concentrations that did not exceed 2µg/ml for metronidazole. Resistant to metronidazole observed in 5.3% of isolates. Forty three (57.3%) of the isolates were resistant to erythromycin. Of 43 resistant strains to erythromycin, 9 (12%) isolates had high-level MIC of more than 64 µg/ml. All strains were resistant to cefotaxime. Sixty seven (89.3%) isolates were resistant to clindamycin (MIC90s > 256 µg/ml) and only 6.7% were sensitive to clindamycin. Multidrug-resistant (three or more antibiotics) was seen in 36(48%) isolates. Conclusions: Metronidazole and vancomycin still seem to be most effective drugs for treatment CDI.

77 citations


Authors

Showing all 19557 results

NameH-indexPapersCitations
Paul F. Jacques11444654507
Mohammad Abdollahi90104535531
Fereidoun Azizi80127941755
Roya Kelishadi7385333681
Nima Rezaei72121526295
Neal D. Freedman6832716908
Jamie E Craig6838015956
Amir Hossein Mahvi6368615816
Adriano G. Cruz6134612832
Ali Montazeri6162517494
Parvin Mirmiran5663715420
Harry A. Lando532429432
Fatemeh Atyabi533109985
Daniel Granato532359406
Pejman Rohani5219213386
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202332
2022187
20214,346
20204,415
20193,809
20183,480