Shahid Beheshti University of Medical Sciences and Health Services

About: Shahid Beheshti University of Medical Sciences and Health Services is a education organization based out in Tehran, Iran. It is known for research contribution in the topics: Population & Cancer. The organization has 19456 authors who have published 33659 publications receiving 365676 citations.

ISG15 deficiency and increased viral resistance in humans but not mice.

Abstract: ISG15 is a ubiquitin-like protein which has important immune-related functions in mice and humans. Here the authors demonstrate that, unlike in mice, human ISG15 stabilizes UPS18 and that ISG15-deficient human cells are more resistant to viral infection.

Coronavirus Pandemic and Worries during Pregnancy;a Letter to Editor

Abstract: Coronavirus (COVID-19) is a new respiratory disease that is spreading widely throughout the world (1). There is no valid information available on pregnant women and their complications. But given previous epidemics (SARS and MERS), as well as mental and physical changes during pregnancy (2), pregnant women are more likely to be exposed. On the other hand, the Coronavirus epidemic has created stress and anxiety for pregnant women in different parts of the world. Concern and stress in pregnancy are associated with side effects such as preeclampsia, preterm labor, depression, low birth weight, increased nausea and vomiting during pregnancy, preterm labor, low birth weight, low APGAR (3-5). In the Coronavirus pandemic, pregnant women cited the following causes of their concerns: - Many pregnant women have had a birth plan before pandemic, but are currently worried about how their families (mothers) will be present, given the urban and quarantine constraints, moreover, even if there is no inter-urban restriction, they may be worried about their families being transferred in transit. - Many pregnant women do not go to work due to concerns that they may be exposed to Coronavirus due to the hospital environment or the route of the hospital and may be postterm. Or even vice versa, because of stress and worry they want an early termination and elective cesarean section. - Many pregnant mothers are employed, constantly using sodium hypochlorite and alcohol detergents to control and prevent the virus, which can lead to poisoning. Some other pregnant mothers, on the other hand, become obsessed with stress and anxiety and are more likely to use these detergents. Some mothers are worried about their fetal or their neonate being born. Also, some mothers worry about postpartum such as breastfeeding, neonatal care (postpartum vaccination, screening). Increasing mothers 'awareness about the transmission of Coronavirus, risk factors, red flags , as well as providing tele counselling for pregnancy care and tele-triage help reduce anxiety and worry. It is also recommended that in cities where home birth and home services are available after birth and home care services, the medical team should provide these services at home while maintaining safety.

Assessing preventive health behaviors from COVID-19: a cross sectional study with health belief model in Golestan Province, Northern of Iran.

Abstract: Coronavirus disease 2019 (COVID-19) is a new viral disease that has caused a pandemic in the world. Due to the lack of vaccines and definitive treatment, preventive behaviors are the only way to overcome the disease. Therefore, the present study aimed to determine the preventive behaviors from the disease based on constructs of the health belief model. In the present cross-sectional study during March 11–16, 2020, 750 individuals in Golestan Province of Iran were included in the study using the convenience sampling and they completed the questionnaires through cyberspace. Factor scores were calculated using the confirmatory factor analysis. The effects of different factors were separately investigated using the univariate analyses, including students sample t-test, ANOVA, and simple linear regression. Finally, the effective factors were examined by the multiple regression analysis at a significant level of 0.05 and through Mplus 7 and SPSS 16. The participants’ mean age was 33.9 ± 9.45 years; and 57.1% of them had associate and bachelor's degrees. Multiple regression indicated that the mean score of preventive behavior from COVID-19 was higher in females than males, and greater in urban dwellers than rural dwellers. Furthermore, one unit increase in the standard deviation of factor scores of self-efficacy and perceived benefits increased the scores of preventive behavior from COVID-19 by 0.22 and 0.17 units respectively. On the contrary, one unit increase in the standard deviation of factor score of perceived barriers and fatalistic beliefs decreased the scores of the preventive behavior from COVID-19 by 0.36 and 0.19 units respectively. Results of the present study indicated that female gender, perceived barriers, perceived self-efficacy, fatalistic beliefs, perceived interests, and living in city had the greatest preventive behaviors from COVID-19 respectively. Preventive interventions were necessary among males and villagers.

Effective variables on production and structure of xanthan gum and its food applications: A review

Abstract: Xanthan gum is a microbial exo-polysaccharide produced industrially from carbon sources by fermentation using the Gram-negative bacterium Xanthomonas campestris. The yield and properties of xanthan gum production and its applications in food are influenced by several variables. Knowing these variables is now needed and will be useful for the scale up production of xanthan gum to achieve high-quality gum at a low price. There have been attempts to optimize variables in xanthan gum production by using various raw materials. This review represents comprehensive knowledge about optimization of effective variables on production and structure of high quality xanthan gum and the applications of xanthan gum for enhancing the quality of foods.

Pattern of acute poisoning in Tehran-Iran in 2003

Abstract: To characterize the poisoning cases admitted to the Loghman-Hakim Hospital Poison Center (a teaching reference hospital of poisoning) in Tehran, Iran. All admitted acutely poisoned patients from January to December 2003 were evaluated retrospectively. Information of socio-demographic characteristics, agents and cause of poisoning, and the mortality rate were collected from medical records of the hospital. During this period, 24 179 cases were referred to the emergency department that 10 206 of them were admitted. Of the admitted cases, 51% were male and 49% female. The majority (38%) of cases were in the age range of 21-30 years. Most (79%) of poisonings were intentional and 21% were unintentional. The most important agents of acute poisoning were drugs (69.13%) especially sedative-hypnotics followed by opioids (12.34%) and pesticides especially organophosphates (OPs) (6.21%). The mortality rate was 1.3% (318 patients). Death was mostly occurred by opioids (41.54%), followed by drugs (28%) and pesticides especially OPs (12%). The prevention and treatment of poisoning due to opioids, pesticides specially OPs and sedative-hypnotics drugs should merit high priority in the health care of the indigenous population of Tehran.