Institution
Shahid Beheshti University of Medical Sciences and Health Services
Education•Tehran, Iran•
About: Shahid Beheshti University of Medical Sciences and Health Services is a education organization based out in Tehran, Iran. It is known for research contribution in the topics: Population & Cancer. The organization has 19456 authors who have published 33659 publications receiving 365676 citations.
Papers published on a yearly basis
Papers
More filters
New York City Department of Health and Mental Hygiene1, University of Groningen2, World Health Organization3, Shahid Beheshti University of Medical Sciences and Health Services4, Statens Serum Institut5, California Department of Public Health6, Rio de Janeiro State University7, Post Graduate Institute of Medical Education and Research8, McGill University9, University of Pennsylvania10, Radboud University Nijmegen11, Institut de recherche pour le développement12, University Health Network13, Albert Einstein College of Medicine14, National Institutes of Health15, Centers for Disease Control and Prevention16, University of Colorado Denver17, Centre for Health Protection18, Oswaldo Cruz Foundation19, University of Cape Town20, University of Sydney21, University of Paris22, Médecins Sans Frontières23, University of California, San Francisco24, Emory University25, Brigham and Women's Hospital26, Samsung Medical Center27, Federal University of Rio de Janeiro28, Hofstra University29, New Generation University College30, Karolinska Institutet31, St. Joseph's Healthcare Hamilton32, Sofia Medical University33, Harvard University34, Columbia University35, Cornell University36, University of Texas Health Science Center at Tyler37, Partners In Health38, University of Ulsan39, University of Sassari40, Queen Mary University of London41, The Chinese University of Hong Kong42
TL;DR: Treatment outcomes were significantly better with use of linezolid, later generation fluoroquinolones, bedaquiline, clofazimine, and carbapenems for treatment of multidrug-resistant tuberculosis, and the need for trials to ascertain the optimal combination and duration of these drugs is emphasised.
404 citations
Huazhong University of Science and Technology1, Icahn School of Medicine at Mount Sinai2, Pasteur Institute3, Boston Children's Hospital4, Shahid Beheshti University of Medical Sciences and Health Services5, Manchester Academic Health Science Centre6, Central South University7, Rockefeller University8, Centre national de la recherche scientifique9, McGill University10, Paris Descartes University11, Howard Hughes Medical Institute12
TL;DR: It is shown here that ISG15-deficient patients also display unanticipated cellular, immunological and clinical signs of enhanced IFN-α/β immunity, reminiscent of the Mendelian autoinflammatory interferonopathies Aicardi–Goutières syndrome and spondyloenchondrodysplasia.
Abstract: Intracellular ISG15 is an interferon (IFN)-α/β-inducible ubiquitin-like modifier which can covalently bind other proteins in a process called ISGylation; it is an effector of IFN-α/β-dependent antiviral immunity in mice. We previously published a study describing humans with inherited ISG15 deficiency but without unusually severe viral diseases. We showed that these patients were prone to mycobacterial disease and that human ISG15 was non-redundant as an extracellular IFN-γ-inducing molecule. We show here that ISG15-deficient patients also display unanticipated cellular, immunological and clinical signs of enhanced IFN-α/β immunity, reminiscent of the Mendelian autoinflammatory interferonopathies Aicardi-Goutieres syndrome and spondyloenchondrodysplasia. We further show that an absence of intracellular ISG15 in the patients' cells prevents the accumulation of USP18, a potent negative regulator of IFN-α/β signalling, resulting in the enhancement and amplification of IFN-α/β responses. Human ISG15, therefore, is not only redundant for antiviral immunity, but is a key negative regulator of IFN-α/β immunity. In humans, intracellular ISG15 is IFN-α/β-inducible not to serve as a substrate for ISGylation-dependent antiviral immunity, but to ensure USP18-dependent regulation of IFN-α/β and prevention of IFN-α/β-dependent autoinflammation.
401 citations
TL;DR: A multi-institution adjudicated case series from Iran which includes 9 pregnant women diagnosed with severe COVID-19 disease during their latter 2nd or 3rd trimester is described, and in each and every instance the maternal outcomes were more severe when compared to other high and low-risk familial/household members.
387 citations
Journal Article•
TL;DR: The SCID was translated into Persian using an elaborate procedure to achieve a satisfactory cross-cultural equivalent and understandability and acceptability of the translated items were assessed in 299 patients in three psychiatric hospitals in Tehran, Iran.
Abstract: The SCID was translated into Persian using an elaborate procedure to achieve a satisfactory cross-cultural equivalent. This included forward translation by bilingual (English/Persian) translators, discussion and revision of the translation in an expert panel of bilingual mental health professionals, pilot assessment on a small sample of Persian–speaking patients, back-translation into English and comparison with the original SCID. In addition, understandability and acceptability of the translated items were assessed in 299 patients in three psychiatric hospitals in Tehran, Iran.
385 citations
TL;DR: The health and disease profile in Iran has made the transition from the dominance of communicable diseases to that of noncommunicable diseases and road traffic injuries.
Abstract: Background
The objective of this study was to estimate the burden of disease and injury in Iran for the year 2003, using Disability-Adjusted Life Years (DALYs) at the national level and for six selected provinces.
381 citations
Authors
Showing all 19557 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Paul F. Jacques | 114 | 446 | 54507 |
| Mohammad Abdollahi | 90 | 1045 | 35531 |
| Fereidoun Azizi | 80 | 1279 | 41755 |
| Roya Kelishadi | 73 | 853 | 33681 |
| Nima Rezaei | 72 | 1215 | 26295 |
| Neal D. Freedman | 68 | 327 | 16908 |
| Jamie E Craig | 68 | 380 | 15956 |
| Amir Hossein Mahvi | 63 | 686 | 15816 |
| Adriano G. Cruz | 61 | 346 | 12832 |
| Ali Montazeri | 61 | 625 | 17494 |
| Parvin Mirmiran | 56 | 637 | 15420 |
| Harry A. Lando | 53 | 242 | 9432 |
| Fatemeh Atyabi | 53 | 310 | 9985 |
| Daniel Granato | 53 | 235 | 9406 |
| Pejman Rohani | 52 | 192 | 13386 |