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Institution

Shanghai Jiao Tong University

EducationShanghai, Shanghai, China
About: Shanghai Jiao Tong University is a education organization based out in Shanghai, Shanghai, China. It is known for research contribution in the topics: Population & Cancer. The organization has 157524 authors who have published 184620 publications receiving 3451038 citations. The organization is also known as: Shanghai Communications University & Shanghai Jiaotong University.


Papers
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Journal ArticleDOI
TL;DR: It is shown that, for any given coupling strength and a suciently large number of cells, the small-world dynamical network will synchronize, even if the original nearest-neighbor coupled network cannot achieve synchronization under the same condition.
Abstract: We investigate synchronization in a network of continuous-time dynamical systems with smallworld connections. The small-world network is obtained by randomly adding a small fraction of connection in an originally nearest-neighbor coupled network. We show that, for any given coupling strength and a suciently large number of cells, the small-world dynamical network will synchronize, even if the original nearest-neighbor coupled network cannot achieve synchronization under the same condition.

814 citations

Journal ArticleDOI
Fengpeng An1, Guangpeng An, Qi An2, Vito Antonelli3  +226 moreInstitutions (55)
TL;DR: The Jiangmen Underground Neutrino Observatory (JUNO) as mentioned in this paper is a 20kton multi-purpose underground liquid scintillator detector with the determination of neutrino mass hierarchy (MH) as a primary physics goal.
Abstract: The Jiangmen Underground Neutrino Observatory (JUNO), a 20 kton multi-purpose underground liquid scintillator detector, was proposed with the determination of the neutrino mass hierarchy (MH) as a primary physics goal. The excellent energy resolution and the large fiducial volume anticipated for the JUNO detector offer exciting opportunities for addressing many important topics in neutrino and astro-particle physics. In this document, we present the physics motivations and the anticipated performance of the JUNO detector for various proposed measurements. Following an introduction summarizing the current status and open issues in neutrino physics, we discuss how the detection of antineutrinos generated by a cluster of nuclear power plants allows the determination of the neutrino MH at a 3–4σ significance with six years of running of JUNO. The measurement of antineutrino spectrum with excellent energy resolution will also lead to the precise determination of the neutrino oscillation parameters ${\mathrm{sin}}^{2}{\theta }_{12}$, ${\rm{\Delta }}{m}_{21}^{2}$, and $| {\rm{\Delta }}{m}_{{ee}}^{2}| $ to an accuracy of better than 1%, which will play a crucial role in the future unitarity test of the MNSP matrix. The JUNO detector is capable of observing not only antineutrinos from the power plants, but also neutrinos/antineutrinos from terrestrial and extra-terrestrial sources, including supernova burst neutrinos, diffuse supernova neutrino background, geoneutrinos, atmospheric neutrinos, and solar neutrinos. As a result of JUNO's large size, excellent energy resolution, and vertex reconstruction capability, interesting new data on these topics can be collected. For example, a neutrino burst from a typical core-collapse supernova at a distance of 10 kpc would lead to ∼5000 inverse-beta-decay events and ∼2000 all-flavor neutrino–proton ES events in JUNO, which are of crucial importance for understanding the mechanism of supernova explosion and for exploring novel phenomena such as collective neutrino oscillations. Detection of neutrinos from all past core-collapse supernova explosions in the visible universe with JUNO would further provide valuable information on the cosmic star-formation rate and the average core-collapse neutrino energy spectrum. Antineutrinos originating from the radioactive decay of uranium and thorium in the Earth can be detected in JUNO with a rate of ∼400 events per year, significantly improving the statistics of existing geoneutrino event samples. Atmospheric neutrino events collected in JUNO can provide independent inputs for determining the MH and the octant of the ${\theta }_{23}$ mixing angle. Detection of the (7)Be and (8)B solar neutrino events at JUNO would shed new light on the solar metallicity problem and examine the transition region between the vacuum and matter dominated neutrino oscillations. Regarding light sterile neutrino topics, sterile neutrinos with ${10}^{-5}\,{{\rm{eV}}}^{2}\lt {\rm{\Delta }}{m}_{41}^{2}\lt {10}^{-2}\,{{\rm{eV}}}^{2}$ and a sufficiently large mixing angle ${\theta }_{14}$ could be identified through a precise measurement of the reactor antineutrino energy spectrum. Meanwhile, JUNO can also provide us excellent opportunities to test the eV-scale sterile neutrino hypothesis, using either the radioactive neutrino sources or a cyclotron-produced neutrino beam. The JUNO detector is also sensitive to several other beyondthe-standard-model physics. Examples include the search for proton decay via the $p\to {K}^{+}+\bar{ u }$ decay channel, search for neutrinos resulting from dark-matter annihilation in the Sun, search for violation of Lorentz invariance via the sidereal modulation of the reactor neutrino event rate, and search for the effects of non-standard interactions. The proposed construction of the JUNO detector will provide a unique facility to address many outstanding crucial questions in particle and astrophysics in a timely and cost-effective fashion. It holds the great potential for further advancing our quest to understanding the fundamental properties of neutrinos, one of the building blocks of our Universe.

807 citations

Posted Content
TL;DR: This paper proposes a novel regional multi-person pose estimation (RMPE) framework to facilitate pose estimation in the presence of inaccurate human bounding boxes and can achieve 76:7 mAP on the MPII (multi person) dataset.
Abstract: Multi-person pose estimation in the wild is challenging. Although state-of-the-art human detectors have demonstrated good performance, small errors in localization and recognition are inevitable. These errors can cause failures for a single-person pose estimator (SPPE), especially for methods that solely depend on human detection results. In this paper, we propose a novel regional multi-person pose estimation (RMPE) framework to facilitate pose estimation in the presence of inaccurate human bounding boxes. Our framework consists of three components: Symmetric Spatial Transformer Network (SSTN), Parametric Pose Non-Maximum-Suppression (NMS), and Pose-Guided Proposals Generator (PGPG). Our method is able to handle inaccurate bounding boxes and redundant detections, allowing it to achieve a 17% increase in mAP over the state-of-the-art methods on the MPII (multi person) dataset.Our model and source codes are publicly available.

804 citations

Journal ArticleDOI
TL;DR: A low-rank factorization model is proposed and a nonlinear successive over-relaxation (SOR) algorithm is constructed that only requires solving a linear least squares problem per iteration to improve the capacity of solving large-scale problems.
Abstract: The matrix completion problem is to recover a low-rank matrix from a subset of its entries. The main solution strategy for this problem has been based on nuclear-norm minimization which requires computing singular value decompositions—a task that is increasingly costly as matrix sizes and ranks increase. To improve the capacity of solving large-scale problems, we propose a low-rank factorization model and construct a nonlinear successive over-relaxation (SOR) algorithm that only requires solving a linear least squares problem per iteration. Extensive numerical experiments show that the algorithm can reliably solve a wide range of problems at a speed at least several times faster than many nuclear-norm minimization algorithms. In addition, convergence of this nonlinear SOR algorithm to a stationary point is analyzed.

801 citations

Journal ArticleDOI
03 Sep 2009-Nature
TL;DR: The generation of several iPS cell lines that are capable of generating viable, fertile live-born progeny by tetraploid complementation and confirm that iPS cells can attain true pluripotency that is similar to that of ES cells.
Abstract: Since iPS (induced pluripotent stem) cells arrived on the scene in 2006, their properties have been measured against the yardstick of the true embryonic stem cells that they mimic. A clutch of recent papers, two of them published in this issue, reports the production of viable adult mice from iPS cells, a notable technical feat that shows that these cells are very close indeed to embryonic cells in their potential to produce cells for all tissues and all organs. Zhao et al. used a technique called tetraploid complementation, in which chimaeric mice are generated from injected pluripotent cells, and the embryonic tissue is derived solely from the injected cells. Boland et al. produced fertile adult mice derived entirely from iPS cells generated by inducible genetic reprogramming of mouse embryonic fibroblasts. The availability of these mice will provide a new resource for the study of iPS cell-derived tissues for both research and cell replacement therapy applications. Induced pluripotent stem (iPS) cells were first created by forced expression of four transcription factors in mouse fibroblasts, a technique that has since been widely used to generate embryonic stem (ES)-cell-like pluripotent cells from a variety of cell types in other species. The generation of several iPS cell lines in mice that are capable of generating viable, fertile live-born progeny by tetraploid complementation — a technique where chimaeric mice are generated using injected pluripotent cells — is now reported. Since the initial description of induced pluripotent stem (iPS) cells created by forced expression of four transcription factors in mouse fibroblasts, the technique has been used to generate embryonic stem (ES)-cell-like pluripotent cells from a variety of cell types in other species, including primates and rat1,2,3,4,5,6. It has become a popular means to reprogram somatic genomes into an embryonic-like pluripotent state, and a preferred alternative to somatic-cell nuclear transfer and somatic-cell fusion with ES cells7,8. However, iPS cell reprogramming remains slow and inefficient. Notably, no live animals have been produced by the most stringent tetraploid complementation assay, indicative of a failure to create fully pluripotent cells. Here we report the generation of several iPS cell lines that are capable of generating viable, fertile live-born progeny by tetraploid complementation. These iPS cells maintain a pluripotent potential that is very close to ES cells generated from in vivo or nuclear transfer embryos. We demonstrate the practicality of using iPS cells as useful tools for the characterization of cellular reprogramming and developmental potency, and confirm that iPS cells can attain true pluripotency that is similar to that of ES cells.

798 citations


Authors

Showing all 158621 results

NameH-indexPapersCitations
Meir J. Stampfer2771414283776
Richard A. Flavell2311328205119
Jie Zhang1784857221720
Yang Yang1712644153049
Lei Jiang1702244135205
Gang Chen1673372149819
Thomas S. Huang1461299101564
Barbara J. Sahakian14561269190
Jean-Laurent Casanova14484276173
Kuo-Chen Chou14348757711
Weihong Tan14089267151
Xin Wu1391865109083
David Y. Graham138104780886
Bin Liu138218187085
Jun Chen136185677368
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023415
20222,315
202120,873
202019,462
201916,699
201814,250